In vivo generated human CAR T cells eradicate tumor cells

by Shiwani Agarwal, Tatjana Weidner, Frederic B. Thalheimer, Christian J. Buchholz
Published 2019-12-01

Monitoring CAR T cell generation with a CD8-targeted lentiviral vector by single-cell transcriptomics

by Filippos T. Charitidis, Elham Adabi, Frederic B. Thalheimer, Colin Clarke, Christian J. Buchholz
Published 2021-12-01

Monitoring CAR T cell generation with a CD8-targeted lentiviral vector by single-cell transcriptomics

by Filippos T. Charitidis, Elham Adabi, Frederic B. Thalheimer, Colin Clarke, Christian J. Buchholz
Published 2022-03-01

1260 Rapid cytokine release syndrome caused by short-term CAR T cells in a preclinical mouse model

by Arezoo Jamali, Naphang Ho, Angela Braun, Elham Adabi, Frederic B Thalheimer, Christian J Buchholz
Published 2023-11-01

Early induction of cytokine release syndrome by rapidly generated CAR T cells in preclinical models

by Arezoo Jamali, Naphang Ho, Angela Braun, Elham Adabi, Frederic B Thalheimer, Christian J Buchholz
Published 2024-03-01

In vivo generation of CAR T cells in the presence of human myeloid cells

by Naphang Ho, Shiwani Agarwal, Michela Milani, Alessio Cantore, Christian J. Buchholz, Frederic B. Thalheimer
Published 2022-09-01

The functional interplay between the t(9;22)-associated fusion proteins BCR/ABL and ABL/BCR in Philadelphia chromosome-positive acute lymphatic leukemia.

by Anahita Rafiei, Afsar Ali Mian, Claudia Döring, Anna Metodieva, Claudia Oancea, Frederic B Thalheimer, Martin Leo Hansmann, Oliver Gerhard Ottmann, Martin Ruthardt
Published 2015-04-01

Tumor-Specific Delivery of Immune Checkpoint Inhibitors by Engineered AAV Vectors

by Johanna Reul, Johanna Reul, Janina Frisch, Christine E. Engeland, Frederic B. Thalheimer, Jessica Hartmann, Guy Ungerechts, Christian J. Buchholz, Christian J. Buchholz
Published 2019-02-01

Cytokine-Regulated GADD45G Induces Differentiation and Lineage Selection in Hematopoietic Stem Cells

by Frederic B. Thalheimer, Susanne Wingert, Pangrazio De Giacomo, Nadine Haetscher, Maike Rehage, Boris Brill, Fabian J. Theis, Lothar Hennighausen, Timm Schroeder, Michael A. Rieger
Published 2014-07-01

CAR Gene Delivery by T‐cell Targeted Lentiviral Vectors is Enhanced by Rapamycin Induced Reduction of Antiviral Mechanisms

by Filippos T Charitidis, Elham Adabi, Naphang Ho, Angela H Braun, Ciara Tierney, Lisa Strasser, Frederic B Thalheimer, Liam Childs, Jonathan Bones, Colin Clarke, Christian J Buchholz
Published 2023-12-01

In vivo generation of human CD19‐CAR T cells results in B‐cell depletion and signs of cytokine release syndrome

by Anett Pfeiffer, Frederic B Thalheimer, Sylvia Hartmann, Annika M Frank, Ruben R Bender, Simon Danisch, Caroline Costa, Winfried S Wels, Ute Modlich, Renata Stripecke, Els Verhoeyen, Christian J Buchholz
Published 2018-11-01

CD62L as target receptor for specific gene delivery into less differentiated human T lymphocytes

by Laura Kapitza, Laura Kapitza, Naphang Ho, Thomas Kerzel, Annika M. Frank, Frederic B. Thalheimer, Arezoo Jamali, Thomas Schaser, Christian J. Buchholz, Christian J. Buchholz, Christian J. Buchholz, Jessica Hartmann
Published 2023-08-01

Single-Stranded DNA-Binding Transcriptional Regulator FUBP1 Is Essential for Fetal and Adult Hematopoietic Stem Cell Self-Renewal

by Uta Rabenhorst, Frederic B. Thalheimer, Katharina Gerlach, Marek Kijonka, Stefanie Böhm, Daniela S. Krause, Franz Vauti, Hans-Henning Arnold, Timm Schroeder, Frank Schnütgen, Harald von Melchner, Michael A. Rieger, Martin Zörnig
Published 2015-06-01

Highly Efficient Generation of Transgenically Augmented CAR NK Cells Overexpressing CXCR4

by Arezoo Jamali, Arezoo Jamali, Arezoo Jamali, Jamshid Hadjati, Zahra Madjd, Zahra Madjd, Hamid Reza Mirzaei, Frederic B. Thalheimer, Shiwani Agarwal, Halvard Bonig, Halvard Bonig, Halvard Bonig, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Jessica Hartmann
Published 2020-08-01