New Kids on the Block: Bile Salt Conjugates of Microbial Origin

by Ümran Ay, Martin Leníček, Arno Classen, Steven W. M. Olde Damink, Carsten Bolm, Frank G. Schaap
Published 2022-02-01

Hepatic Steatosis Contributes to the Development of Muscle Atrophy via Inter-Organ Crosstalk

by Kenneth Pasmans, Michiel E. Adriaens, Peter Olinga, Ramon Langen, Sander S. Rensen, Frank G. Schaap, Frank G. Schaap, Steven W. M. Olde Damink, Steven W. M. Olde Damink, Florian Caiment, Luc J. C. van Loon, Ellen E. Blaak, Ruth C. R. Meex
Published 2021-10-01

Differential Effects of One Meal per Day in the Evening on Metabolic Health and Physical Performance in Lean Individuals

by Emma C. E. Meessen, Håvard Andresen, Thomas van Barneveld, Anne van Riel, Egil I. Johansen, Anders J. Kolnes, E. Marleen Kemper, Steven W. M. Olde Damink, Steven W. M. Olde Damink, Frank G. Schaap, Frank G. Schaap, Johannes A. Romijn, Jørgen Jensen, Maarten R. Soeters
Published 2022-01-01

Lipocalin-2 and neutrophil activation in pancreatic cancer cachexia

by Min Deng, Merel R. Aberle, Annemarie A. J. H. M. van Bijnen, Gregory van der Kroft, Gregory van der Kroft, Kaatje Lenaerts, Ulf P. Neumann, Ulf P. Neumann, Georg Wiltberger, Frank G. Schaap, Frank G. Schaap, Steven W. M. Olde Damink, Steven W. M. Olde Damink, Sander S. Rensen
Published 2023-03-01

Pharmacological activation of the bile acid nuclear farnesoid X receptor is feasible in patients with quiescent Crohn's colitis.

by Fiona D M van Schaik, Raffaella M Gadaleta, Frank G Schaap, Saskia W C van Mil, Peter D Siersema, Bas Oldenburg, Karel J van Erpecum
Published 2012-01-01

Age-Dependent Differences in Postprandial Bile-Acid Metabolism and the Role of the Gut Microbiome

by Soumia Majait, Emma C. E. Meessen, Mark Davids, Youssef Chahid, Steven W. Olde Damink, Frank G. Schaap, Ellis Marleen Kemper, Max Nieuwdorp, Maarten R. Soeters
Published 2024-04-01

<i>Eggerthella lenta</i> DSM 2243 Alleviates Bile Acid Stress Response in <i>Clostridium ramosum</i> and <i>Anaerostipes caccae</i> by Transformation of Bile Acids

by Kristian Jensen Pedersen, Sven-Bastiaan Haange, Kateřina Žížalová, Alina Viehof, Thomas Clavel, Martin Leniček, Beatrice Engelmann, Lukas Y. Wick, Frank G. Schaap, Nico Jehmlich, Ulrike Rolle-Kampczyk, Martin von Bergen
Published 2022-10-01

ApoE2-associated hypertriglyceridemia is ameliorated by increased levels of apoA-V but unaffected by apoC-III deficiency*

by Gery Gerritsen, Caroline C. van der Hoogt, Frank G. Schaap, Peter J. Voshol, Kyriakos E. Kypreos, Nobuyo Maeda, Albert K. Groen, Louis M. Havekes, Patrick C.N. Rensen, Ko Willems van Dijk
Published 2008-05-01

Evidence for a complex relationship between apoA-V and apoC-III in patients with severe hypertriglyceridemia

by Frank G. Schaap, Melchior C. Nierman, Jimmy F.P. Berbée, Hiroaki Hattori, Philippa J. Talmud, Stefan F.C. Vaessen, Patrick C.N. Rensen, Robert A.F.M. Chamuleau, Jan Albert Kuivenhoven, Albert K. Groen
Published 2006-10-01

Characterization of Postprandial Bile Acid Profiles and Glucose Metabolism in Cerebrotendinous Xanthomatosis

by Soumia Majait, Emma C. E. Meessen, Frederic Maxime Vaz, E. Marleen Kemper, Samuel van Nierop, Steven W. Olde Damink, Frank G. Schaap, Johannes A. Romijn, Max Nieuwdorp, Aad Verrips, Filip Krag Knop, Maarten R. Soeters
Published 2023-10-01

Cathepsin D regulates lipid metabolism in murine steatohepatitis

by Tom Houben, Yvonne Oligschlaeger, Tim Hendrikx, Albert V. Bitorina, Sofie M. A. Walenbergh, Patrick J. van Gorp, Marion J. J. Gijbels, Silvia Friedrichs, Jogchum Plat, Frank G. Schaap, Dieter Lütjohann, Marten H. Hofker, Ronit Shiri-Sverdlov
Published 2017-06-01

Effect of wheat bran derived prebiotic supplementation on gastrointestinal transit, gut microbiota, and metabolic health: a randomized controlled trial in healthy adults with a slo...

by Mattea Müller, Gerben D. A. Hermes, Canfora Emanuel E., Jens J. Holst, Erwin G. Zoetendal, Hauke Smidt, Freddy Troost, Frank G. Schaap, Steven Olde Damink, Johan W. E. Jocken, Kaatje Lenaerts, Ad A. M. Masclee, Ellen E. Blaak
Published 2020-11-01

Impact of global Fxr deficiency on experimental acute pancreatitis and genetic variation in the FXR locus in human acute pancreatitis.

by Rian M Nijmeijer, Frank G Schaap, Alexander J J Smits, Andreas E Kremer, Louis M A Akkermans, Alfons B A Kroese, Ger T Rijkers, Marguerite E I Schipper, André Verheem, Cisca Wijmenga, Hein G Gooszen, Karel J van Erpecum
Published 2014-01-01

Unaltered Liver Regeneration in Post-Cholestatic Rats Treated with the FXR Agonist Obeticholic Acid

by Lianne R. de Haan, Joanne Verheij, Rowan F. van Golen, Verena Horneffer-van der Sluis, Matthew R. Lewis, Ulrich H. W. Beuers, Thomas M. van Gulik, Steven W. M. Olde Damink, Frank G. Schaap, Michal Heger, Pim B. Olthof
Published 2021-02-01

Bile Salt and FGF19 Signaling in the Early Phase of Human Liver Regeneration

by Kiran V.K. Koelfat, Kim M.C. vanMierlo, Toine M. Lodewick, Johanne G. Bloemen, Gregory van derKroft, Iakovos Amygdalos, Ulf P. Neumann, Cornelis H.C. Dejong, Peter L.M. Jansen, Steven W.M. Olde Damink, Frank G. Schaap
Published 2021-08-01

Ring Trial on Quantitative Assessment of Bile Acids Reveals a Method- and Analyte-Specific Accuracy and Reproducibility

by Sven-Bastiaan Haange, Andreas Till, Per-Olof Bergh, Günter Fauler, Michael Gigl, Anita Löfgren-Sandblom, Frank G. Schaap, Thomas Clavel, Christian Trautwein, Wiebke Fenske, Karin Kleigrewe, Hanns-Ulrich Marschall, Steven W. M. Olde Damink, Tarek Moustafa, Martin von Bergen, Ulrike Rolle-Kampczyk
Published 2022-06-01

Apolipoprotein A-V, triglycerides and risk of coronary artery disease: the prospective Epic-Norfolk Population Study

by Stefan F.C. Vaessen, Frank G. Schaap, Jan-Albert Kuivenhoven, Albert K. Groen, Barbara A. Hutten, S. Matthijs Boekholdt, Hiroaki Hattori, Manjinder S. Sandhu, Sheila A. Bingham, Robert Luben, Jutta A. Palmen, Nicholas J. Wareham, Steve E. Humphries, John J.P. Kastelein, Philippa J. Talmud, Kay-Tee Khaw
Published 2006-09-01

Distinct fecal and oral microbiota composition in human type 1 diabetes, an observational study.

by Pieter F de Groot, Clara Belzer, Ömrüm Aydin, Evgeni Levin, Johannes H Levels, Steven Aalvink, Fransje Boot, Frits Holleman, Daniël H van Raalte, Torsten P Scheithauer, Suat Simsek, Frank G Schaap, Steven W M Olde Damink, Bart O Roep, Joost B Hoekstra, Willem M de Vos, Max Nieuwdorp
Published 2017-01-01