Acquisition of cancer stem cell capacities after spontaneous cell fusion

by Candice Merle, Pauline Lagarde, Lydia Lartigue, Frédéric Chibon
Published 2021-03-01

The CINSARC signature as a prognostic marker for clinical outcome in multiple neoplasms

by Tom Lesluyes, Lucile Delespaul, Jean-Michel Coindre, Frédéric Chibon
Published 2017-07-01

Cell fusion enhances energy metabolism of mesenchymal tumor hybrid cells to sustain their proliferation and invasion

by Ariadna Brito, Candice Merle, Pauline Lagarde, Benjamin Faustin, Anne Devin, Lydia Lartigue, Frederic Chibon
Published 2021-07-01

Recurrent DMD Deletions Highlight Specific Role of Dp71 Isoform in Soft-Tissue Sarcomas

by Olivier Mauduit, Vanessa Delcroix, Tom Lesluyes, Gaëlle Pérot, Pauline Lagarde, Lydia Lartigue, Jean-Yves Blay, Frédéric Chibon
Published 2019-07-01

Germinal GLT8D1, GATAD2A and SLC25A39 mutations in a patient with a glomangiopericytal tumor and five different sarcomas over a 10-year period

by Arnaud Beddok, Gaëlle Pérot, Sophie Le Guellec, Noémie Thebault, Alexandre Coutte, Henri Sevestre, Bruno Chauffert, Frédéric Chibon
Published 2021-05-01

Primary multicentric angiosarcoma of bone: true entity or metastases from an unknown primary? Value of comparative genomic hybridization on paraffin embedded tissues

by Juliette Thariat, Isabelle Peyrottes, Frédéric Chibon, Maxime Benchetrit, Esma Saada, Lauris Gastaud, Olivier Dassonville, Antoine Iannessi, Antione Thyss
Published 2013-09-01

Tetraploidization of Immortalized Myoblasts Induced by Cell Fusion Drives Myogenic Sarcoma Development with <em>DMD</em> Deletion

by Candice Merle, Noémie Thébault, Sophie LeGuellec, Jessica Baud, Gaëlle Pérot, Tom Lesluyes, Lucile Delespaul, Lydia Lartigue, Frédéric Chibon
Published 2020-05-01

Prognostic value of PLAGL1-specific CpG site methylation in soft-tissue sarcomas.

by Anne-Lise Peille, Veronique Brouste, Audrey Kauffmann, Pauline Lagarde, Valerie Le Morvan, Jean-Michel Coindre, Frederic Chibon, Laurence Bresson-Bepoldin
Published 2013-01-01

Greatwall promotes cell transformation by hyperactivating AKT in human malignancies

by Jorge Vera, Lydia Lartigue, Suzanne Vigneron, Gilles Gadea, Veronique Gire, Maguy Del Rio, Isabelle Soubeyran, Frederic Chibon, Thierry Lorca, Anna Castro
Published 2015-11-01

The Role of the Anti-Aging Protein Klotho in IGF-1 Signaling and Reticular Calcium Leak: Impact on the Chemosensitivity of Dedifferentiated Liposarcomas

by Vanessa Delcroix, Olivier Mauduit, Nolwenn Tessier, Anaïs Montillaud, Tom Lesluyes, Thomas Ducret, Frédéric Chibon, Fabien Van Coppenolle, Sylvie Ducreux, Pierre Vacher
Published 2018-11-01

Identification of a recurrent STRN/ALK fusion in thyroid carcinomas.

by Gaëlle Pérot, Isabelle Soubeyran, Agnès Ribeiro, Benjamin Bonhomme, Frédérique Savagner, Nathalie Boutet-Bouzamondo, Isabelle Hostein, Françoise Bonichon, Yann Godbert, Frédéric Chibon
Published 2014-01-01

Cell–cell fusion of mesenchymal cells with distinct differentiations triggers genomic and transcriptomic remodelling toward tumour aggressiveness

by Lucile Delespaul, Caroline Gélabert, Tom Lesluyes, Sophie Le Guellec, Gaëlle Pérot, Laura Leroy, Jessica Baud, Candice Merle, Lydia Lartigue, Frédéric Chibon
Published 2020-12-01

Value of peri-operative chemotherapy in patients with CINSARC high-risk localized grade 1 or 2 soft tissue sarcoma: study protocol of the target selection phase III CHIC-STS trial

by Thomas Filleron, Sophie Le Guellec, Christine Chevreau, Bastien Cabarrou, Tom Lesluyes, Sabrina Lodin, Angélique Massoubre, Muriel Mounier, Muriel Poublanc, Frédéric Chibon, Thibaud Valentin
Published 2020-07-01

MED12 alterations in both human benign and malignant uterine soft tissue tumors.

by Gaëlle Pérot, Sabrina Croce, Agnès Ribeiro, Pauline Lagarde, Valérie Velasco, Agnès Neuville, Jean-Michel Coindre, Eberhard Stoeckle, Anne Floquet, Gaëtan MacGrogan, Frédéric Chibon
Published 2012-01-01

Heterogeneous Mechanisms of Secondary Resistance and Clonal Selection in Sarcoma during Treatment with Nutlin.

by Audrey Laroche, Kevin Tran-Cong, Vanessa Chaire, Pauline Lagarde, Isabelle Hostein, Jean-Michel Coindre, Frederic Chibon, Agnes Neuville, Tom Lesluyes, Carlo Lucchesi, Antoine Italiano
Published 2015-01-01

Pan Aurora Kinase Inhibitor: A Promising Targeted-Therapy in Dedifferentiated Liposarcomas With Differential Efficiency Depending on Sarcoma Molecular Profile

by Jean Camille Mattei, Corinne Bouvier-Labit, Doriane Barets, Nicolas Macagno, Mathieu Chocry, Frédéric Chibon, Philippe Morando, Richard Alexandre Rochwerger, Florence Duffaud, Sylviane Olschwang, Sébastien Salas, Carine Jiguet-Jiglaire
Published 2020-03-01

Analysis of the Peritumoral Tissue Unveils Cellular Changes Associated with a High Risk of Recurrence

by Audrey Michot, Pauline Lagarde, Tom Lesluyes, Elodie Darbo, Agnès Neuville, Jessica Baud, Gaëlle Perot, Iris Bonomo, Mathilde Maire, Maxime Michot, Jean-Michel Coindre, François Le Loarer, Frédéric Chibon
Published 2023-06-01

RCBTB1 Deletion Is Associated with Metastatic Outcome and Contributes to Docetaxel Resistance in Nontranslocation-Related Pleomorphic Sarcomas

by Olivier Mauduit, Céline Brulard, Tom Lesluyes, Vanessa Delcroix, Gaëlle Pérot, Nina Choublier, Mickael Michaud, Jessica Baud, Pauline Lagarde, Alain Aurias, Jean-Michel Coindre, Lydia Lartigue, Jean-Yves Blay, Frédéric Chibon
Published 2019-01-01

Comprehensive Immune Profiling Unveils a Subset of Leiomyosarcoma with “Hot” Tumor Immune Microenvironment

by Xiaolan Feng, Laurie Tonon, Haocheng Li, Elodie Darbo, Erin Pleasance, Nicolas Macagno, Armelle Dufresne, Mehdi Brahmi, Julien Bollard, Francoise Ducimetière, Marie Karanian, Alexandra Meurgey, Gaëlle Pérot, Thibaud Valentin, Frédéric Chibon, Jean-Yves Blay
Published 2023-07-01

ATRX Alteration Contributes to Tumor Growth and Immune Escape in Pleomorphic Sarcomas

by Lucie Darmusey, Gaëlle Pérot, Noémie Thébault, Sophie Le Guellec, Nelly Desplat, Laëtitia Gaston, Lucile Delespaul, Tom Lesluyes, Elodie Darbo, Anne Gomez-Brouchet, Elodie Richard, Jessica Baud, Laura Leroy, Jean-Michel Coindre, Jean-Yves Blay, Frédéric Chibon
Published 2021-04-01