BRCA1/MAD2L1 deficiency disrupts the spindle assembly checkpoint to confer vinorelbine resistance in mesothelioma

by Busacca, S., O'Regan, L., Singh, A., Sharkey, A.J., Dawson, A.G., Dzialo, J., Parsons, A., Kumar, N., Schunselaar, L.M., Guppy, N., Nakas, A., Sheaff, M., Mansfield, A.S., Janes, S.M., Baas, P., Fry, A.M., Fennell, D.A.
Published 2021

Mesothelioma and Radical Surgery 2 (MARS 2): protocol for a multicentre randomised trial comparing (extended) pleurectomy decortication versus no (extended) pleurectomy decorticati...

by Lim, Eric, Darlison, Liz, Edwards, John, Elliott, Daisy, Fennell, DA, Popat, Sanjay, Rintoul, Robert C, Waller, David, Ali, Clinton, Bille, Andrea, Fuller, Liz, Ionescu, Andreea, Keni, Manjusha, Kirk, Alan, Koh, Pek, Lau, Kelvin, Mansy, Talal, Maskell, Nick A, Milton, Richard, Muthukumar, Dakshinamoorthy, Pope, Tony, Roy, Amy, Shah, Riyaz, Shamash, Jonathan, Tasigiannopoulos, Zacharias, Taylor, Paul, Treece, Sarah, Ashton, Kate, Harris, Rosie, Joyce, Katherine, Warnes, Barbara, Mills, Nicola, Stokes, Elizabeth A, Rogers, Chris, MARS 2 Trialists
Published 2021

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.

by Abbosh, C, Birkbak, NJ, Wilson, GA, Jamal-Hanjani, M, Constantin, T, Salari, R, Le Quesne, J, Moore, DA, Veeriah, S, Rosenthal, R, Marafioti, T, Kirkizlar, E, Watkins, TBK, McGranahan, N, Ward, S, Martinson, L, Riley, J, Fraioli, F, Al Bakir, M, Grönroos, E, Zambrana, F, Endozo, R, Bi, WL, Fennessy, FM, Sponer, N, Johnson, D, Laycock, J, Shafi, S, Czyzewska-Khan, J, Rowan, A, Chambers, T, Matthews, N, Turajlic, S, Hiley, C, Lee, SM, Forster, MD, Ahmad, T, Falzon, M, Borg, E, Lawrence, D, Hayward, M, Kolvekar, S, Panagiotopoulos, N, Janes, SM, Thakrar, R, Ahmed, A, Blackhall, F, Summers, Y, Hafez, D, Naik, A, Ganguly, A, Kareht, S, Shah, R, Joseph, L, Marie Quinn, A, Crosbie, PA, Naidu, B, Middleton, G, Langman, G, Trotter, S, Nicolson, M, Remmen, H, Kerr, K, Chetty, M, Gomersall, L, Fennell, DA, Nakas, A, Rathinam, S, Anand, G, Khan, S, Russell, P, Ezhil, V, Ismail, B, Irvin-Sellers, M, Prakash, V, Lester, JF, Kornaszewska, M, Attanoos, R, Adams, H, Davies, H, Oukrif, D, Akarca, AU, Hartley, JA, Lowe, HL, Lock, S, Iles, N, Bell, H, Ngai, Y, Elgar, G, Szallasi, Z, Schwarz, RF, Herrero, J, Stewart, A, Quezada, SA, Peggs, KS, Van Loo, P, Dive, C, Lin, CJ, Rabinowitz, M, Aerts, HJWL, Hackshaw, A, Shaw, JA, Zimmermann, BG, TRACERx consortium, PEACE consortium, Swanton, C
Published 2019