Integrative rare disease biomedical profile based network supporting drug repurposing or repositioning, a case study of glioblastoma

by Erin McGowan, Jaleal Sanjak, Ewy A. Mathé, Qian Zhu
Published 2023-09-01

Self-organizing maps with variable neighborhoods facilitate learning of chromatin accessibility signal shapes associated with regulatory elements

by Tara Eicher, Jany Chan, Han Luu, Raghu Machiraju, Ewy A. Mathé
Published 2021-01-01

Exploring NCATS in-house biomedical data for evidence-based drug repurposing.

by Fang Liu, Andrew Patt, Chloe Chen, Ruili Huang, Yanji Xu, Ewy A Mathé, Qian Zhu
Published 2024-01-01

Exploring NCATS in-house biomedical data for evidence-based drug repurposing

by Fang Liu, Andrew Patt, Chloe Chen, Ruili Huang, Yanji Xu, Ewy A. Mathé, Qian Zhu
Published 2024-01-01

Metabolomics and Multi-Omics Integration: A Survey of Computational Methods and Resources

by Tara Eicher, Garrett Kinnebrew, Andrew Patt, Kyle Spencer, Kevin Ying, Qin Ma, Raghu Machiraju, Ewy A. Mathé
Published 2020-05-01

Scientific evidence based rare disease research discovery with research funding data in knowledge graph

by Qian Zhu, Ðắc-Trung Nguyễn, Timothy Sheils, Gioconda Alyea, Eric Sid, Yanji Xu, James Dickens, Ewy A. Mathé, Anne Pariser
Published 2021-11-01

Identification of transcription factor co-regulators that drive prostate cancer progression

by Manjunath Siddappa, Sajad A. Wani, Mark D. Long, Damien A. Leach, Ewy A. Mathé, Charlotte L. Bevan, Moray J. Campbell
Published 2020-11-01

IntLIM: integration using linear models of metabolomics and gene expression data

by Jalal K. Siddiqui, Elizabeth Baskin, Mingrui Liu, Carmen Z. Cantemir-Stone, Bofei Zhang, Russell Bonneville, Joseph P. McElroy, Kevin R. Coombes, Ewy A. Mathé
Published 2018-03-01

MDM2-Dependent Rewiring of Metabolomic and Lipidomic Profiles in Dedifferentiated Liposarcoma Models

by Andrew Patt, Bryce Demoret, Colin Stets, Kate-Lynn Bill, Philip Smith, Anitha Vijay, Andrew Patterson, John Hays, Mindy Hoang, James L. Chen, Ewy A. Mathé
Published 2020-08-01

Development and validation of PAMPA-BBB QSAR model to predict brain penetration potential of novel drug candidates

by Rintaro Kato, Wenyu Zeng, Vishal B. Siramshetty, Jordan Williams, Md Kabir, Natalie Hagen, Elias C. Padilha, Amy Q. Wang, Ewy A. Mathé, Xin Xu, Pranav Shah
Published 2023-12-01

Nucleotide, Phospholipid, and Kynurenine Metabolites Are Robustly Associated with COVID-19 Severity and Time of Plasma Sample Collection in a Prospective Cohort Study

by Haley A. S. Chatelaine, Yulu Chen, John Braisted, Su H. Chu, Qingwen Chen, Meryl Stav, Sofina Begum, Joann Diray-Arce, Jaleal Sanjak, Mengna Huang, Jessica Lasky-Su, Ewy A. Mathé
Published 2023-12-01

A Pilot Cross-Sectional Study of Immunological and Microbiome Profiling Reveals Distinct Inflammatory Profiles for Smokers, Electronic Cigarette Users, and Never-Smokers

by Peter G. Shields, Kevin L. Ying, Theodore M. Brasky, Jo L. Freudenheim, Zihai Li, Joseph P. McElroy, Sarah A. Reisinger, Min-Ae Song, Daniel Y. Weng, Mark D. Wewers, Noah B. Whiteman, Yiping Yang, Ewy A. Mathé
Published 2023-05-01

The value of prospective metabolomic susceptibility endotypes: broad applicability for infectious diseasesResearch in context

by Yulu Chen, Kevin Mendez, Sofina Begum, Emily Dean, Haley Chatelaine, John Braisted, Vrushali D. Fangal, Margaret Cote, Mengna Huang, Su H. Chu, Meryl Stav, Qingwen Chen, Nicole Prince, Rachel Kelly, Kenneth B. Christopher, Joann Diray-Arce, Ewy A. Mathé, Jessica Lasky-Su
Published 2023-10-01

DEIA is essential to advance the goals of translational science: Perspectives from NCATS

by Shadab F. Hussain, Amanda L. Vogel, Jessica M. Faupel-Badger, Linda Ho, Lameese D. Akacem, Krishna Balakrishnan, Rebekah Geiger, Rashmi Gopal-Srivastava, Brittany Haynes, Marcus G. Hodges, Tanetta Isler, Ewy A. Mathé, Leonie Misquitta, Karlie R. Sharma, Eric Sid, Jamie L. Zigterman, Penny W. Burgoon
Published 2023-01-01

A Path to Real-World Evidence in Critical Care Using Open-Source Data Harmonization Tools

by Smith F. Heavner, PhD, RN, Wesley Anderson, PhD, Rahul Kashyap, MBBS, MBA, Pamela Dasher, BA, Ewy A. Mathé, PhD, Laura Merson, Philippe J. Guerin, MD, PhD, Jeff Weaver, MBA, Matthew Robinson, MD, Marco Schito, PhD, Vishakha K. Kumar, MD, MBA, Paul Nagy, PhD
Published 2023-04-01