GeneSetCluster: a tool for summarizing and integrating gene-set analysis results

by Ewoud Ewing, Nuria Planell-Picola, Maja Jagodic, David Gomez-Cabrero
Published 2020-10-01

Transcriptomic Profiling Reveals That HMGB1 Induces Macrophage Polarization Different from Classical M1

by Heshuang Qu, Rebecka Heinbäck, Henna Salo, Ewoud Ewing, Alexander Espinosa, Cecilia Aulin, Helena Erlandsson Harris
Published 2022-06-01

Usability of human Infinium MethylationEPIC BeadChip for mouse DNA methylation studies

by Maria Needhamsen, Ewoud Ewing, Harald Lund, David Gomez-Cabrero, Robert Adam Harris, Lara Kular, Maja Jagodic
Published 2017-11-01

DNA methylation changes in glial cells of the normal-appearing white matter in Multiple Sclerosis patients

by Lara Kular, Ewoud Ewing, Maria Needhamsen, Majid Pahlevan Kakhki, Ruxandra Covacu, David Gomez-Cabrero, Lou Brundin, Maja Jagodic
Published 2022-11-01

Simultaneous detection of DNA variation and methylation at HLA class II locus and immune gene promoters using targeted SureSelect Methyl-Sequencing

by Maria Kalomoiri, Chandana Rao Prakash, Sonja Lagström, Kai Hauschulz, Ewoud Ewing, Klementy Shchetynsky, Lara Kular, Maria Needhamsen, Maja Jagodic
Published 2023-08-01

Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas-Casp8-Bid-axis

by Karl E. Carlström, Keying Zhu, Ewoud Ewing, Inge E. Krabbendam, Robert A. Harris, Ana Mendanha Falcão, Maja Jagodic, Gonçalo Castelo-Branco, Fredrik Piehl
Published 2020-08-01

Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progressionResearch in co...

by Ewoud Ewing, Lara Kular, Sunjay J. Fernandes, Nestoras Karathanasis, Vincenzo Lagani, Sabrina Ruhrmann, Ioannis Tsamardinos, Jesper Tegner, Fredrik Piehl, David Gomez-Cabrero, Maja Jagodic
Published 2019-05-01

Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

by Lara Kular, Maria Needhamsen, Milena Z. Adzemovic, Tatiana Kramarova, David Gomez-Cabrero, Ewoud Ewing, Eliane Piket, Jesper Tegnér, Stephan Beck, Fredrik Piehl, Lou Brundin, Maja Jagodic
Published 2019-05-01

Epigenetic clock indicates accelerated aging in glial cells of progressive multiple sclerosis patients

by Lara Kular, Dennis Klose, Amaya Urdánoz-Casado, Amaya Urdánoz-Casado, Ewoud Ewing, Nuria Planell, David Gomez-Cabrero, David Gomez-Cabrero, David Gomez-Cabrero, David Gomez-Cabrero, Maria Needhamsen, Maja Jagodic
Published 2022-08-01

Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells

by Harald Lund, Melanie Pieber, Roham Parsa, Jinming Han, David Grommisch, Ewoud Ewing, Lara Kular, Maria Needhamsen, Alexander Espinosa, Emma Nilsson, Anna K. Överby, Oleg Butovsky, Maja Jagodic, Xing-Mei Zhang, Robert A. Harris
Published 2018-11-01

Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes

by Karl E. Carlström, Ewoud Ewing, Mathias Granqvist, Alexandra Gyllenberg, Shahin Aeinehband, Sara Lind Enoksson, Antonio Checa, Tejaswi V. S. Badam, Jesse Huang, David Gomez-Cabrero, Mika Gustafsson, Faiez Al Nimer, Craig E. Wheelock, Ingrid Kockum, Tomas Olsson, Maja Jagodic, Fredrik Piehl
Published 2019-07-01

STATegra: Multi-Omics Data Integration – A Conceptual Scheme With a Bioinformatics Pipeline

by Nuria Planell, Vincenzo Lagani, Vincenzo Lagani, Patricia Sebastian-Leon, Frans van der Kloet, Ewoud Ewing, Nestoras Karathanasis, Nestoras Karathanasis, Arantxa Urdangarin, Imanol Arozarena, Maja Jagodic, Ioannis Tsamardinos, Ioannis Tsamardinos, Sonia Tarazona, Ana Conesa, Ana Conesa, Jesper Tegner, Jesper Tegner, Jesper Tegner, David Gomez-Cabrero, David Gomez-Cabrero, David Gomez-Cabrero, David Gomez-Cabrero
Published 2021-03-01

DNA Methylation Signatures of Multiple Sclerosis Occur Independently of Known Genetic Risk and Are Primarily Attributed to B Cells and Monocytes

by Alexandre Xavier, Vicki E. Maltby, Ewoud Ewing, Maria Pia Campagna, Sean M. Burnard, Jesper N. Tegner, Mark Slee, Helmut Butzkueven, Ingrid Kockum, Lara Kular, Ausimmune/AusLong Investigators Group, Vilija G. Jokubaitis, Trevor Kilpatrick, Lars Alfredsson, Maja Jagodic, Anne-Louise Ponsonby, Bruce V. Taylor, Rodney J. Scott, Rodney A. Lea, Jeannette Lechner-Scott
Published 2023-08-01

DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis

by Lara Kular, Yun Liu, Sabrina Ruhrmann, Galina Zheleznyakova, Francesco Marabita, David Gomez-Cabrero, Tojo James, Ewoud Ewing, Magdalena Lindén, Bartosz Górnikiewicz, Shahin Aeinehband, Pernilla Stridh, Jenny Link, Till F. M. Andlauer, Christiane Gasperi, Heinz Wiendl, Frauke Zipp, Ralf Gold, Björn Tackenberg, Frank Weber, Bernhard Hemmer, Konstantin Strauch, Stefanie Heilmann-Heimbach, Rajesh Rawal, Ulf Schminke, Carsten O. Schmidt, Tim Kacprowski, Andre Franke, Matthias Laudes, Alexander T. Dilthey, Elisabeth G. Celius, Helle B. Søndergaard, Jesper Tegnér, Hanne F. Harbo, Annette B. Oturai, Sigurgeir Olafsson, Hannes P. Eggertsson, Bjarni V. Halldorsson, Haukur Hjaltason, Elias Olafsson, Ingileif Jonsdottir, Kari Stefansson, Tomas Olsson, Fredrik Piehl, Tomas J. Ekström, Ingrid Kockum, Andrew P. Feinberg, Maja Jagodic
Published 2018-06-01