The orphan ligand, activin C, signals through activin receptor-like kinase 7

by Erich J Goebel, Luisina Ongaro, Emily C Kappes, Kylie Vestal, Elitza Belcheva, Roselyne Castonguay, Ravindra Kumar, Daniel J Bernard, Thomas B Thompson
Published 2022-06-01

How Activin A Became a Therapeutic Target in Fibrodysplasia Ossificans Progressiva

by Dushyanth Srinivasan, Martin Arostegui, Erich J. Goebel, Kaitlin N. Hart, Senem Aykul, John B. Lees-Shepard, Vincent Idone, Sarah J. Hatsell, Aris N. Economides
Published 2024-01-01

Structures of activin ligand traps using natural sets of type I and type II TGFβ receptors

by Erich J. Goebel, Chandramohan Kattamuri, Gregory R. Gipson, Lavanya Krishnan, Moises Chavez, Magdalena Czepnik, Michelle C. Maguire, Rosa Grenha, Maria Håkansson, Derek T. Logan, Asya V. Grinberg, Dianne Sako, Roselyne Castonguay, Ravindra Kumar, Thomas B. Thompson
Published 2022-01-01

Activin A forms a non-signaling complex with ACVR1 and type II Activin/BMP receptors via its finger 2 tip loop

by Senem Aykul, Richard A Corpina, Erich J Goebel, Camille J Cunanan, Alexandra Dimitriou, Hyon Jong Kim, Qian Zhang, Ashique Rafique, Raymond Leidich, Xin Wang, Joyce McClain, Johanna Jimenez, Kalyan C Nannuru, Nyanza J Rothman, John B Lees-Shepard, Erik Martinez-Hackert, Andrew J Murphy, Thomas B Thompson, Aris N Economides, Vincent Idone
Published 2020-06-01