Toll-Like Receptor Initiated Host Defense against Toxoplasma gondii

by Eric Y. Denkers
Published 2010-01-01

Toxoplasma gondii inhibits covalent modification of histone H3 at the IL-10 promoter in infected macrophages.

by Jin Leng, Eric Y Denkers
Published 2009-10-01

From Initiators to Effectors: Roadmap Through the Intestine During Encounter of Toxoplasma gondii With the Mucosal Immune System

by Lindsay M. Snyder, Eric Y. Denkers
Published 2021-01-01

Transcriptomics analysis of Toxoplasma gondii-infected mouse macrophages reveals coding and noncoding signatures in the presence and absence of MyD88

by Kayla L. Menard, Lijing Bu, Eric Y. Denkers
Published 2021-02-01

Impact of Toxoplasma gondii Infection on Host Non-coding RNA Responses

by Kayla L. Menard, Breanne E. Haskins, Eric Y. Denkers
Published 2019-05-01

Toxoplasma gondii triggers phosphorylation and nuclear translocation of dendritic cell STAT1 while simultaneously blocking IFNγ-induced STAT1 transcriptional activity.

by Anne G Schneider, Delbert S Abi Abdallah, Barbara A Butcher, Eric Y Denkers
Published 2013-01-01

Phagocyte responses to protozoan infection and how Toxoplasma gondii meets the challenge.

by Eric Y Denkers, Anne G Schneider, Sara B Cohen, Barbara A Butcher
Published 2012-01-01

Induction of IL-12p40 and type 1 immunity by Toxoplasma gondii in the absence of the TLR-MyD88 signaling cascade.

by Lindsay M Snyder, Claire M Doherty, Heather L Mercer, Eric Y Denkers
Published 2021-10-01

CXCR3-dependent CD4⁺ T cells are required to activate inflammatory monocytes for defense against intestinal infection.

by Sara B Cohen, Kirk J Maurer, Charlotte E Egan, Steve Oghumu, Abhay R Satoskar, Eric Y Denkers
Published 2013-01-01

CCR2 and CD44 promote inflammatory cell recruitment during fatty liver formation in a lithogenic diet fed mouse model.

by Charlotte E Egan, Erin K Daugherity, Arlin B Rogers, Delbert S Abi Abdallah, Eric Y Denkers, Kirk J Maurer
Published 2013-01-01

Toxoplasma gondii dense granule protein GRA24 drives MyD88-independent p38 MAPK activation, IL-12 production and induction of protective immunity.

by Heather L Mercer, Lindsay M Snyder, Claire M Doherty, Barbara A Fox, David J Bzik, Eric Y Denkers
Published 2020-05-01

Inflammation drives dysbiosis and bacterial invasion in murine models of ileal Crohn's disease.

by Melanie Craven, Charlotte E Egan, Scot E Dowd, Sean P McDonough, Belgin Dogan, Eric Y Denkers, Dwight Bowman, Ellen J Scherl, Kenneth W Simpson
Published 2012-01-01

Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control.

by Barbara A Butcher, Barbara A Fox, Leah M Rommereim, Sung Guk Kim, Kirk J Maurer, Felix Yarovinsky, De'Broski R Herbert, David J Bzik, Eric Y Denkers
Published 2011-09-01

Differential Regulation of Effector- and Central-Memory Responses to Toxoplasma gondii Infection by IL-12 Revealed by Tracking of Tgd057-Specific CD8+ T Cells

by Wilson, Douglas C., Grotenbreg, Gijsbert M., Liu, Kenian, Zhao, Yanlin, Frickel, Eva-Maria, Gubbels, Marc-Jan, Yap, George S., Ploegh, Hidde
Published 2018