Synergistic growth-inhibitory effects of ponatinib and midostaurin (PKC412) on neoplastic mast cells carrying KIT D816V

by Karoline V. Gleixner, Barbara Peter, Katharina Blatt, Verena Suppan, Andreas Reiter, Deepti Radia, Emir Hadzijusufovic, Peter Valent
Published 2013-09-01

Co-operating STAT5 and AKT signaling pathways in chronic myeloid leukemia and mastocytosis: possible new targets of therapy

by Siham Bibi, Melis Dilara Arslanhan, Florent Langenfeld, Sylvie Jeanningros, Sabine Cerny-Reiterer, Emir Hadzijusufovic, Luba Tchertanov, Richard Moriggl, Peter Valent, Michel Arock
Published 2014-03-01

Efficacy and Synergy of Small Molecule Inhibitors Targeting <i>FLT3</i>-ITD⁺ Acute Myeloid Leukemia

by Javier Bregante, Anna Schönbichler, Daniel Pölöske, Lina Degenfeld-Schonburg, Garazi Monzó Contreras, Emir Hadzijusufovic, Elvin D. de Araujo, Peter Valent, Richard Moriggl, Anna Orlova
Published 2021-12-01

Phenotyping of human melanoma cells reveals a unique composition of receptor targets and a subpopulation co-expressing ErbB4, EPO-R and NGF-R.

by Irina Mirkina, Emir Hadzijusufovic, Clemens Krepler, Mario Mikula, Diana Mechtcheriakova, Sabine Strommer, Alexander Stella, Erika Jensen-Jarolim, Christoph Höller, Volker Wacheck, Hubert Pehamberger, Peter Valent
Published 2014-01-01

Proposed Diagnostic Criteria and Classification of Canine Mast Cell Neoplasms: A Consensus Proposal

by Michael Willmann, Michael Willmann, Vilma Yuzbasiyan-Gurkan, Laura Marconato, Mauro Dacasto, Emir Hadzijusufovic, Emir Hadzijusufovic, Emir Hadzijusufovic, Olivier Hermine, Irina Sadovnik, Irina Sadovnik, Susanne Gamperl, Susanne Gamperl, Mathias Schneeweiss-Gleixner, Mathias Schneeweiss-Gleixner, Karoline V. Gleixner, Thomas Böhm, Barbara Peter, Barbara Peter, Gregor Eisenwort, Gregor Eisenwort, Richard Moriggl, Zhixiong Li, Mohamad Jawhar, Karl Sotlar, Erika Jensen-Jarolim, Erika Jensen-Jarolim, Veronika Sexl, Hans-Peter Horny, Hans-Peter Horny, Stephen J. Galli, Stephen J. Galli, Michel Arock, David M. Vail, David M. Vail, Matti Kiupel, Peter Valent, Peter Valent
Published 2021-12-01

The PI3-kinase/mTOR-targeting drug NVP-BEZ235 inhibits growth and IgE-dependent activation of human mast cells and basophils.

by Katharina Blatt, Harald Herrmann, Irina Mirkina, Emir Hadzijusufovic, Barbara Peter, Sabine Strommer, Gregor Hoermann, Matthias Mayerhofer, Konrad Hoetzenecker, Walter Klepetko, Viviane Ghanim, Katharina Marth, Thorsten Füreder, Volker Wacheck, Rudolf Valenta, Peter Valent
Published 2012-01-01

Polo-like kinase-1 as a novel target in neoplastic mast cells: demonstration of growth-inhibitory effects of small interfering RNA and the Polo-like kinase-1 targeting drug BI 2536

by Barbara Peter, Karoline V. Gleixner, Sabine Cerny-Reiterer, Harald Herrmann, Viviane Winter, Emir Hadzijusufovic, Veronika Ferenc, Karina Schuch, Irina Mirkina, Hans-Peter Horny, Winfried F. Pickl, Leonhard Müllauer, Michael Willmann, Peter Valent
Published 2011-05-01

The KIT and PDGFRA switch-control inhibitor DCC-2618 blocks growth and survival of multiple neoplastic cell types in advanced mastocytosis

by Mathias Schneeweiss, Barbara Peter, Siham Bibi, Gregor Eisenwort, Dubravka Smiljkovic, Katharina Blatt, Mohamad Jawhar, Daniela Berger, Gabriele Stefanzl, Susanne Herndlhofer, Georg Greiner, Gregor Hoermann, Emir Hadzijusufovic, Karoline V. Gleixner, Peter Bettelheim, Klaus Geissler, Wolfgang R. Sperr, Andreas Reiter, Michel Arock, Peter Valent
Published 2018-05-01

STAT5 is Expressed in CD34⁺/CD38⁻ Stem Cells and Serves as a Potential Molecular Target in Ph-Negative Myeloproliferative Neoplasms

by Emir Hadzijusufovic, Alexandra Keller, Daniela Berger, Georg Greiner, Bettina Wingelhofer, Nadine Witzeneder, Daniel Ivanov, Emmanuel Pecnard, Harini Nivarthi, Florian K. M. Schur, Yüksel Filik, Christoph Kornauth, Heidi A. Neubauer, Leonhard Müllauer, Gary Tin, Jisung Park, Elvin D. de Araujo, Patrick T. Gunning, Gregor Hoermann, Fabrice Gouilleux, Robert Kralovics, Richard Moriggl, Peter Valent
Published 2020-04-01