Molecular Basis of Bicyclic Boronate β-Lactamase Inhibitors of Ultrabroad Efficacy – Insights From Molecular Dynamics Simulation Studies

by Emilio Lence, Concepción González-Bello
Published 2021-08-01

Novel Penicillin-Based Sulfone-Siderophore Conjugates for Restoring β‑Lactam Antibiotic Efficacy

by Diana Rodríguez, Emilio Lence, Juan C. Vázquez-Ucha, Alejandro Beceiro, Concepción González-Bello
Published 2024-05-01

Photobinding of Triflusal to Human Serum Albumin Investigated by Fluorescence, Proteomic Analysis, and Computational Studies

by Oscar Molins-Molina, Raúl Pérez-Ruiz, Emilio Lence, Concepción González-Bello, Miguel A. Miranda, M. Consuelo Jiménez
Published 2019-09-01

Quinate-based ligands for irreversible inactivation of the bacterial virulence factor DHQ1 enzyme—A molecular insight†

by Ángela Rodríguez, María Maneiro, Emilio Lence, José M. Otero, Mark J. van Raaij, Paul Thompson, Alastair R. Hawkins, Concepción González-Bello
Published 2023-01-01

Protein Binding of Lapatinib and Its N- and O-Dealkylated Metabolites Interrogated by Fluorescence, Ultrafast Spectroscopy and Molecular Dynamics Simulations

by Inmaculada Andreu, Inmaculada Andreu, Emilio Lence, Concepción González-Bello, Cristobalina Mayorga, M. Consuelo Cuquerella, M. Consuelo Cuquerella, Ignacio Vayá, Ignacio Vayá, Miguel A. Miranda, Miguel A. Miranda
Published 2020-10-01

Modulation of the photobehavior of gefitinib and its phenolic metabolites by human transport proteins

by Lorena Tamarit, Lorena Tamarit, Meryem El Ouardi, Meryem El Ouardi, Emilio Lence, Inmaculada Andreu, Inmaculada Andreu, Concepcion González-Bello, Miguel A. Miranda, Miguel A. Miranda, Ignacio Vayá, Ignacio Vayá
Published 2024-05-01

Crambescin C1 Acts as A Possible Substrate of iNOS and eNOS Increasing Nitric Oxide Production and Inducing In Vivo Hypotensive Effect

by Juan A. Rubiolo, Juan A. Rubiolo, Emilio Lence, Concepción González-Bello, María Roel, José Gil-Longo, Manuel Campos-Toimil, Manuel Campos-Toimil, Eva Ternon, Olivier P. Thomas, Antonio González-Cantalapiedra, Henar López-Alonso, Mercedes R. Vieytes, Luis M. Botana
Published 2021-07-01