HIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells.

by Malinda R Schaefer, Elizabeth R Wonderlich, Jeremiah F Roeth, Jolie A Leonard, Kathleen L Collins
Published 2008-08-01

Blocking TLR7- and TLR9-mediated IFN-α production by plasmacytoid dendritic cells does not diminish immune activation in early SIV infection.

by Muhamuda Kader, Amanda P Smith, Cristiana Guiducci, Elizabeth R Wonderlich, Daniel Normolle, Simon C Watkins, Franck J Barrat, Simon M Barratt-Boyes
Published 2013-01-01

Infiltration of inflammatory macrophages and neutrophils and widespread pyroptosis in lung drive influenza lethality in nonhuman primates.

by Jacqueline Corry, Gwenddolen Kettenburg, Amit A Upadhyay, Megan Wallace, Michelle M Marti, Elizabeth R Wonderlich, Stephanie J Bissel, Kyndal Goss, Timothy J Sturgeon, Simon C Watkins, Douglas S Reed, Steven E Bosinger, Simon M Barratt-Boyes
Published 2022-03-01

Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals.

by Elizabeth R Wonderlich, Krupa Subramanian, Bryan Cox, Ann Wiegand, Carol Lackman-Smith, Michael J Bale, Mars Stone, Rebecca Hoh, Mary F Kearney, Frank Maldarelli, Steven G Deeks, Michael P Busch, Roger G Ptak, Deanna A Kulpa
Published 2019-10-01

Application of ultrasensitive digital ELISA for p24 enables improved evaluation of HIV-1 reservoir diversity and growth kinetics in viral outgrowth assays

by Yury V. Kuzmichev, Carol Lackman-Smith, Sonia Bakkour, Ann Wiegand, Michael J. Bale, Andrew Musick, Wendy Bernstein, Naomi Aronson, Julie Ake, Sodsai Tovanabutra, Mars Stone, Roger G. Ptak, Mary F. Kearney, Michael P. Busch, Elizabeth R. Wonderlich, Deanna A. Kulpa
Published 2023-07-01

Novel Compound Inhibitors of HIV-1_NL4-3 Vpu

by Carolyn A. Robinson, Terri D. Lyddon, Hwi Min Gil, David T. Evans, Yury V. Kuzmichev, Jonathan Richard, Andrés Finzi, Sarah Welbourn, Lynn Rasmussen, N. Miranda Nebane, Vandana V. Gupta, Sam Ananthan, Zhaohui Cai, Elizabeth R. Wonderlich, Corinne E. Augelli-Szafran, Robert Bostwick, Roger G. Ptak, Susan M. Schader, Marc C. Johnson
Published 2022-04-01

A highly multiplexed droplet digital PCR assay to measure the intact HIV-1 proviral reservoir

by Claire N. Levy, Sean M. Hughes, Pavitra Roychoudhury, Daniel B. Reeves, Chelsea Amstuz, Haiying Zhu, Meei-Li Huang, Yulun Wei, Marta E. Bull, Noah A.J. Cassidy, Jan McClure, Lisa M. Frenkel, Mars Stone, Sonia Bakkour, Elizabeth R. Wonderlich, Michael P. Busch, Steven G. Deeks, Joshua T. Schiffer, Robert W. Coombs, Dara A. Lehman, Keith R. Jerome, Florian Hladik
Published 2021-04-01

Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection.

by Michelle Y-H Lee, Amit A Upadhyay, Hasse Walum, Chi N Chan, Reem A Dawoud, Christine Grech, Justin L Harper, Kirti A Karunakaran, Sydney A Nelson, Ernestine A Mahar, Kyndal L Goss, Diane G Carnathan, Barbara Cervasi, Kiran Gill, Gregory K Tharp, Elizabeth R Wonderlich, Vijayakumar Velu, Simon M Barratt-Boyes, Mirko Paiardini, Guido Silvestri, Jacob D Estes, Steven E Bosinger
Published 2021-06-01

Single center, open label dose escalating trial evaluating once weekly oral ixazomib in ART-suppressed, HIV positive adults and effects on HIV reservoir size in vivo.

by Nathan W Cummins, Jason Baker, Rana Chakraborty, Patrick G Dean, Enrique Garcia-Rivera, Ashton Krogman, Shaji Kumar, Yury V Kuzmichev, Gregory M Laird, Alan Landay, Mathias Lichterfeld, Maryam Mahmood, Jeffrey Martinson, Mark Maynes, Sekar Natesampillai, Vincent Rajkumar, Yelizaveta Rassadkina, Kristen D. Ritter, Christina G Rivera, Stacey A Rizza, Krupa Subramanian, Aaron J Tande, Elizabeth R Wonderlich, Jennifer A Whitaker, John Zeuli, Andrew D Badley
Published 2021-12-01

The 2000HIV study: Design, multi-omics methods and participant characteristics

by Wilhelm A. J. W. Vos, Wilhelm A. J. W. Vos, Albert L. Groenendijk, Albert L. Groenendijk, Marc J. T. Blaauw, Marc J. T. Blaauw, Louise E. van Eekeren, Adriana Navas, Maartje C. P. Cleophas, Nadira Vadaq, Vasiliki Matzaraki, Jéssica C. dos Santos, Elise M. G. Meeder, Elise M. G. Meeder, Elise M. G. Meeder, Janeri Fröberg, Gert Weijers, Yue Zhang, Jingyuan Fu, Rob ter Horst, Christoph Bock, Christoph Bock, Rainer Knoll, Rainer Knoll, Anna C. Aschenbrenner, Anna C. Aschenbrenner, Joachim Schultze, Joachim Schultze, Joachim Schultze, Linos Vanderkerckhove, Talent Hwandih, Elizabeth R. Wonderlich, Sai V. Vemula, Mike van der Kolk, Sterre C. P. de Vet, Willem L. Blok, Kees Brinkman, Casper Rokx, Arnt F. A. Schellekens, Arnt F. A. Schellekens, Arnt F. A. Schellekens, Quirijn de Mast, Leo A. B. Joosten, Leo A. B. Joosten, Marvin A. H. Berrevoets, Janneke E. Stalenhoef, Annelies Verbon, Jan van Lunzen, Mihai G. Netea, Mihai G. Netea, Andre J. A. M. van der Ven
Published 2022-12-01