Alterations of protein homeostasis in Alzheimer's disease: beyond Procrustean bed of endoplasmic reticulum stress and unfolded protein response

by Dmitry Lim, Alexei Verkhratsky
Published 2024-01-01

Probing the endoplasmic reticulum-mitochondria interaction in Alzheimer’s disease: searching far and wide

by Giulia Dematteis, Laura Tapella, Dmitry Lim
Published 2024-01-01

Molecular Aspects of Cellular Dysfunction in Alzheimer’s Disease: The Need for a Holistic View of the Early Pathogenesis

by Sara Merlo, Simona Federica Spampinato, Dmitry Lim
Published 2021-12-01

Neuronal Activity-Dependent Activation of Astroglial Calcineurin in Mouse Primary Hippocampal Cultures

by Dmitry Lim, Lisa Mapelli, Pier Luigi Canonico, Francesco Moccia, Armando A. Genazzani
Published 2018-09-01

Intracellular Ca2+ signalling: unexpected new roles for the usual suspect

by Francesco Moccia, Alessandra Fiorio Pla, Dmitry Lim, Francesco Lodola, Francesco Lodola, Andrea Gerbino
Published 2023-07-01

Calcineurin Controls Expression of EAAT1/GLAST in Mouse and Human Cultured Astrocytes through Dynamic Regulation of Protein Synthesis and Degradation

by Giulia Dematteis, Elena Restelli, Roberto Chiesa, Eleonora Aronica, Armando A Genazzani, Dmitry Lim, Laura Tapella
Published 2020-03-01

The Cytokine Nicotinamide Phosphoribosyltransferase (eNAMPT; PBEF; Visfatin) Acts as a Natural Antagonist of C-C Chemokine Receptor Type 5 (CCR5)

by Simone Torretta, Giorgia Colombo, Cristina Travelli, Sara Boumya, Dmitry Lim, Armando A. Genazzani, Ambra A. Grolla
Published 2020-02-01

Quantification of the Chemical Chaperone 4-Phenylbutyric Acid (4-PBA) in Cell Culture Media via LC-HRMS: Applications in Fields of Neurodegeneration and Cancer

by Salvatore Villani, Giulia Dematteis, Laura Tapella, Mara Gagliardi, Dmitry Lim, Marco Corazzari, Silvio Aprile, Erika Del Grosso
Published 2023-02-01

Calcineurin Controls Cellular Prion Protein Expression in Mouse Astrocytes

by Giulia Dematteis, Elena Restelli, Virginia Vita Vanella, Marcello Manfredi, Emilio Marengo, Marco Corazzari, Armando A. Genazzani, Roberto Chiesa, Dmitry Lim, Laura Tapella
Published 2022-02-01

Store-Operated Ca²⁺ Entry Is Up-Regulated in Tumour-Infiltrating Lymphocytes from Metastatic Colorectal Cancer Patients

by Pawan Faris, Agnese Rumolo, Laura Tapella, Matteo Tanzi, Alessia Metallo, Filippo Conca, Sharon Negri, Konstantinos Lefkimmiatis, Paolo Pedrazzoli, Dmitry Lim, Daniela Montagna, Francesco Moccia
Published 2022-07-01

Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Induces Intracellular Ca²⁺ Release through the Two-Pore Channel TPC1 in Metastatic Colorectal Cancer Cells

by Pawan Faris, Giorgia Pellavio, Federica Ferulli, Francesca Di Nezza, Mudhir Shekha, Dmitry Lim, Marcello Maestri, Germano Guerra, Luigi Ambrosone, Paolo Pedrazzoli, Umberto Laforenza, Daniela Montagna, Francesco Moccia
Published 2019-04-01

The novel mouse mutation Oblivion inactivates the PMCA2 pump and causes progressive hearing loss.

by Sarah L Spiden, Mario Bortolozzi, Francesca Di Leva, Martin Hrabé de Angelis, Helmut Fuchs, Dmitry Lim, Saida Ortolano, Neil J Ingham, Marisa Brini, Ernesto Carafoli, Fabio Mammano, Karen P Steel
Published 2008-10-01

Early Stimulation of TREK Channel Transcription and Activity Induced by Oxaliplatin-Dependent Cytosolic Acidification

by Marianna Dionisi, Federico Alessandro Ruffinatti, Beatrice Riva, Dmitry Lim, Annalisa Canta, Cristina Meregalli, Giulia Fumagalli, Laura Monza, Antonio Ferrer-Montiel, Asia Fernandez-Carvajal, Guido Cavaletti, Armando A. Genazzani, Carla Distasi
Published 2020-09-01

A Metabologenomic approach reveals alterations in the gut microbiota of a mouse model of Alzheimer's disease.

by Francesco Favero, Elettra Barberis, Mara Gagliardi, Stefano Espinoza, Liliana Contu, Stefano Gustincich, Francesca Boccafoschi, Chiara Borsotti, Dmitry Lim, Vito Rubino, Flavio Mignone, Edoardo Pasolli, Marcello Manfredi, Silvia Zucchelli, Davide Corà, Marco Corazzari
Published 2022-01-01

Susceptibility of different mouse strains to oxaliplatin peripheral neurotoxicity: Phenotypic and genotypic insights.

by Paola Marmiroli, Beatrice Riva, Eleonora Pozzi, Elisa Ballarini, Dmitry Lim, Alessia Chiorazzi, Cristina Meregalli, Carla Distasi, Cynthia L Renn, Sara Semperboni, Lavinia Morosi, Federico A Ruffinatti, Massimo Zucchetti, Susan G Dorsey, Guido Cavaletti, Armando Genazzani, Valentina A Carozzi
Published 2017-01-01

Store-operated Ca2+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients.

by Francesco Lodola, Umberto Laforenza, Elisa Bonetti, Dmitry Lim, Silvia Dragoni, Cinzia Bottino, Hwei Ling Ong, Germano Guerra, Carlo Ganini, Margherita Massa, Mariangela Manzoni, Indu S Ambudkar, Armando A Genazzani, Vittorio Rosti, Paolo Pedrazzoli, Franco Tanzi, Francesco Moccia, Camillo Porta
Published 2012-01-01

Ring finger protein 10 is a novel synaptonuclear messenger encoding activation of NMDA receptors in hippocampus

by Margarita C Dinamarca, Francesca Guzzetti, Anna Karpova, Dmitry Lim, Nico Mitro, Stefano Musardo, Manuela Mellone, Elena Marcello, Jennifer Stanic, Tanmoy Samaddar, Adeline Burguière, Antonio Caldarelli, Armando A Genazzani, Julie Perroy, Laurent Fagni, Pier Luigi Canonico, Michael R Kreutz, Fabrizio Gardoni, Monica Di Luca
Published 2016-03-01

Protein synthesis inhibition and loss of homeostatic functions in astrocytes from an Alzheimer’s disease mouse model: a role for ER-mitochondria interaction

by Laura Tapella, Giulia Dematteis, Marianna Moro, Beatrice Pistolato, Elisa Tonelli, Virginia Vita Vanella, Daniele Giustina, Aleida La Forgia, Elena Restelli, Elettra Barberis, Tito Cali, Marisa Brini, Salvatore Villani, Erika Del Grosso, Mariagrazia Grilli, Marcello Manfredi, Marco Corazzari, Ambra A. Grolla, Armando A. Genazzani, Dmitry Lim
Published 2022-10-01