Quantification of cell-free mSHOX2 Plasma DNA for therapy monitoring in advanced stage non-small cell (NSCLC) and small-cell lung cancer (SCLC) patients.

by Bernd Schmidt, Julia Beyer, Dimo Dietrich, Ines Bork, Volker Liebenberg, Michael Fleischhacker
Published 2015-01-01

Clinical performance validation of PITX2 DNA methylation as prognostic biomarker in patients with head and neck squamous cell carcinoma.

by Verena Sailer, Heidrun Gevensleben, Joern Dietrich, Diane Goltz, Glen Kristiansen, Friedrich Bootz, Dimo Dietrich
Published 2017-01-01

Feasibility of Monitoring Response to Metastatic Prostate Cancer Treatment with a Methylation-Based Circulating Tumor DNA Approach

by Thomas Büttner, Dimo Dietrich, Romina Zarbl, Niklas Klümper, Jörg Ellinger, Philipp Krausewitz, Manuel Ritter
Published 2024-01-01

PD-1 (PDCD1) Promoter Methylation Is a Prognostic Factor in Patients With Diffuse Lower-Grade Gliomas Harboring Isocitrate Dehydrogenase (IDH) Mutations

by Lea Kristin Röver, Heidrun Gevensleben, Jörn Dietrich, Friedrich Bootz, Jennifer Landsberg, Diane Goltz, Dimo Dietrich
Published 2018-02-01

Improved PCR performance using template DNA from formalin-fixed and paraffin-embedded tissues by overcoming PCR inhibition.

by Dimo Dietrich, Barbara Uhl, Verena Sailer, Emily Eva Holmes, Maria Jung, Sebastian Meller, Glen Kristiansen
Published 2013-01-01

Comparison of quantification algorithms for circulating cell-free DNA methylation biomarkers in blood plasma from cancer patients

by Luka de Vos, Heidrun Gevensleben, Andreas Schröck, Alina Franzen, Glen Kristiansen, Friedrich Bootz, Dimo Dietrich
Published 2017-12-01

Intragenic DNA methylation of PITX1 and the adjacent long non-coding RNA C5orf66-AS1 are prognostic biomarkers in patients with head and neck squamous cell carcinomas.

by Verena Sailer, Arthur Charpentier, Joern Dietrich, Timo J Vogt, Alina Franzen, Friedrich Bootz, Dimo Dietrich, Andreas Schroeck
Published 2018-01-01

Detailed analysis of adenosine A2a receptor (ADORA2A) and CD73 (5′-nucleotidase, ecto, NT5E) methylation and gene expression in head and neck squamous cell carcinoma patients

by Timo J. Vogt, Heidrun Gevensleben, Jörn Dietrich, Glen Kristiansen, Friedrich Bootz, Jennifer Landsberg, Diane Goltz, Dimo Dietrich
Published 2018-08-01

Upregulation of the long non-coding RNA CASC9 as a biomarker for squamous cell carcinoma

by Madeleine Sassenberg, Johanna Droop, Wolfgang A. Schulz, Dimo Dietrich, Sophia Marie Loick, Constanze Wiek, Kathrin Scheckenbach, Nadine T. Gaisa, Michèle J. Hoffmann
Published 2019-08-01

Diagnostic and prognostic value of SHOX2 and SEPT9 DNA methylation and cytology in benign, paramalignant and malignant pleural effusions.

by Dimo Dietrich, Maria Jung, Svenja Puetzer, Annette Leisse, Emily Eva Holmes, Sebastian Meller, Barbara Uhl, Philipp Schatz, Claudia Ivascu, Glen Kristiansen
Published 2013-01-01

Systematic Analysis of the Expression of the Mitochondrial ATP Synthase (Complex V) Subunits in Clear Cell Renal Cell Carcinoma

by Maria Brüggemann, Arabella Gromes, Mirjam Poss, Doris Schmidt, Niklas Klümper, Yuri Tolkach, Dimo Dietrich, Glen Kristiansen, Stefan C Müller, Jörg Ellinger
Published 2017-08-01

A novel method for sensitive and specific detection of DNA methylation biomarkers based on DNA restriction during PCR cycling

by Christoph Kneip, Bernd Schmidt, Michael Fleischhacker, Anke Seegebarth, Jörn Lewin, Nadja Flemming, Stefanie Seemann, Thomas Schlegel, Christian Witt, Volker Liebenberg, Dimo Dietrich
Published 2009-09-01

The landscape of CD28, CD80, CD86, CTLA4, and ICOS DNA methylation in head and neck squamous cell carcinomas

by Luka de Vos, Ingela Grünwald, Emma Grace Bawden, Jörn Dietrich, Kathrin Scheckenbach, Constanze Wiek, Romina Zarbl, Friedrich Bootz, Jennifer Landsberg, Dimo Dietrich
Published 2020-11-01

Performance evaluation of kits for bisulfite-conversion of DNA from tissues, cell lines, FFPE tissues, aspirates, lavages, effusions, plasma, serum, and urine.

by Emily Eva Holmes, Maria Jung, Sebastian Meller, Annette Leisse, Verena Sailer, Julie Zech, Martina Mengdehl, Leif-Alexander Garbe, Barbara Uhl, Glen Kristiansen, Dimo Dietrich
Published 2014-01-01

DNA Methylation of PITX2 and PANCR Is Prognostic for Overall Survival in Patients with Resected Adenocarcinomas of the Biliary Tract.

by Barbara Uhl, Dimo Dietrich, Vittorio Branchi, Alexander Semaan, Pauline Schaefer, Heidrun Gevensleben, Babak Rostamzadeh, Philipp Lingohr, Nico Schäfer, Jörg C Kalff, Glen Kristiansen, Hanno Matthaei
Published 2016-01-01

Comprehensive analysis of tumor necrosis factor receptor TNFRSF9 (4-1BB) DNA methylation with regard to molecular and clinicopathological features, immune infiltrates, and response...

by Anne Fröhlich, Sophia Loick, Emma Grace Bawden, Simon Fietz, Jörn Dietrich, Eric Diekmann, Gonzalo Saavedra, Holger Fröhlich, Dennis Niebel, Judith Sirokay, Romina Zarbl, Gerrit H. Gielen, Glen Kristiansen, Friedrich Bootz, Jennifer Landsberg, Dimo Dietrich
Published 2020-02-01

DNA methylation of indoleamine 2,3-dioxygenase 1 (IDO1) in head and neck squamous cell carcinomas correlates with IDO1 expression, HPV status, patients’ survival, immune cell infil...

by Verena Sailer, Ulrike Sailer, Emma Grace Bawden, Romina Zarbl, Constanze Wiek, Timo J. Vogt, Joern Dietrich, Sophia Loick, Ingela Grünwald, Marieta Toma, Carsten Golletz, Andreas Gerstner, Glen Kristiansen, Friedrich Bootz, Kathrin Scheckenbach, Jennifer Landsberg, Dimo Dietrich
Published 2019-10-01

Prognostic Significance and Functional Role of CEP57 in Prostate Cancer

by Josef Mang, Nina Korzeniewski, Dimo Dietrich, Verena Sailer, Yanis Tolstov, Sam Searcy, Jost von Hardenberg, Sven Perner, Glen Kristiansen, Alexander Marx, Wilfried Roth, Esther Herpel, Carsten Grüllich, Valentin Popeneciu, Sascha Pahernik, Boris Hadaschik, Markus Hohenfellner, Stefan Duensing
Published 2015-12-01

ICOS DNA methylation regulates melanoma cell-intrinsic ICOS expression, is associated with melanoma differentiation, prognosis, and predicts response to immune checkpoint blockade

by Damian J. Ralser, Emmanuelle Herr, Luka de Vos, Zsófi Kulcsár, Romina Zarbl, Niklas Klümper, Gerrit H. Gielen, Alexander Philippe Maas, Friederike Hoffmann, Jörn Dietrich, Pia Kuster, Alexander Mustea, Nicole Glodde, Glen Kristiansen, Sebastian Strieth, Jennifer Landsberg, Dimo Dietrich
Published 2023-06-01

CTLA4 DNA methylation is associated with CTLA-4 expression and predicts response to immunotherapy in head and neck squamous cell carcinoma

by Friederike Hoffmann, Alina Franzen, Luka de Vos, Lennert Wuest, Zsófi Kulcsár, Simon Fietz, Alexander Philippe Maas, Sarah Hollick, Marie Yatou Diop, Jennis Gabrielpillai, Timo Vogt, Pia Kuster, Romina Zarbl, Joern Dietrich, Glen Kristiansen, Peter Brossart, Jennifer Landsberg, Sebastian Strieth, Dimo Dietrich
Published 2023-07-01