Design and development of novel inhibitors for the treatment of latent tuberculosis

by Rudraraju Srilakshmi Reshma, Perumal Yogeeswari, Dharmarajan Sriram
Published 2016-01-01

Optimization and validation of Mycobacterium marinum-induced adult zebrafish model for evaluation of oral anti-tuberculosis drugs

by Jonnalagadda Padma Sridevi, Hasitha Shilpa Anantaraju, Pushkar Kulkarni, Perumal Yogeeswari, Dharmarajan Sriram
Published 2014-01-01

Design and Synthesis of “Chloropicolinate Amides and Urea Derivatives” as Novel Inhibitors for Mycobacterium tuberculosis

by Srihari Konduri, Dodda Bhargavi, Jyothi Prashanth, Vagolu Siva Krishna, Dharmarajan Sriram, Koya Prabhakara Rao
Published 2021-01-01

Salicylanilide Diethyl Phosphates as Potential Inhibitors of Some Mycobacterial Enzymes

by Martin Krátký, Eva Novotná, Shalini Saxena, Perumal Yogeeswari, Dharmarajan Sriram, Markéta Švarcová, Jarmila Vinšová
Published 2014-01-01

A stereo, regioselective synthesis and discovery of antimycobaterium tuberculosis activity of novel β-lactam grafted spirooxindolopyrrolidine hybrid heterocycles

by Natarajan Arumugam, Abdulrahman I. Almansour, Raju Suresh Kumar, Vagolu Siva Krishna, Dharmarajan Sriram, Ramanathan Padmanaban
Published 2021-02-01

Benzothiazinone-piperazine derivatives as efficient Mycobacterium tuberculosis DNA gyrase inhibitors

by Manoj Chandran, Janupally Renuka, Jonnalagadda Padma Sridevi, Ganesh S Pedgaonkar, Vanaparthi Asmitha, Perumal Yogeeswari, Dharmarajan Sriram
Published 2015-01-01

Synthesis and Biological Evaluation of Novel Benzhydrylpiperazine-Coupled Nitrobenzenesulfonamide Hybrids

by Vallabhaneni S. Murthy, Yasinalli Tamboli, Vagolu Siva Krishna, Dharmarajan Sriram, Fang Xiong Zhang, Gerald W. Zamponi, Vijayaparthasarathi Vijayakumar
Published 2021-03-01

Imidazo[2,1‑b]thiazole-Coupled Natural Noscapine Derivatives as Anticancer Agents

by Praveen Kumar Reddy Nagireddy, Vamsi Krishna Kommalapati, Vagolu Siva Krishna, Dharmarajan Sriram, Anjana Devi Tangutur, Srinivas Kantevari
Published 2019-11-01

Depletion of M. tuberculosis GlmU from Infected Murine Lungs Effects the Clearance of the Pathogen.

by Vijay Soni, Sandeep Upadhayay, Priyanka Suryadevara, Ganesh Samla, Archana Singh, Perumal Yogeeswari, Dharmarajan Sriram, Vinay Kumar Nandicoori
Published 2015-10-01

Investigating structure–activity relationship and mechanism of action of antitubercular 1-(4-chlorophenyl)-4-(4-hydroxy-3-methoxy-5-nitrobenzylidene) pyrazolidine-3,5-dione [CD59]...

by Ganesh Samala, Shruti Singh Kakan, Radhika Nallangi, Parthiban Brindha Devi, Jonnalagadda Padma Sridevi, Shalini Saxena, Perumal Yogeeswari, Dharmarajan Sriram
Published 2014-01-01

Discovery of potent antimycobacterial agents targeting lumazine synthase (RibH) of Mycobacterium tuberculosis

by Monica Singh, Anannya Dhanwal, Arpita Verma, Linus Augustin, Niti Kumari, Soumyananda Chakraborti, Nisheeth Agarwal, Dharmarajan Sriram, Ruchi Jain Dey
Published 2024-05-01

Design and characterisation of piperazine-benzofuran integrated dinitrobenzenesulfonamide as Mycobacterium tuberculosis H37Rv strain inhibitors

by Vallabhaneni S. Murthy, Yasinalli Tamboli, Vagolu Siva Krishna, Dharmarajan Sriram, Siddique Akber Ansari, Abdullah A. Alarfaj, Abdurahman H. Hirad, Vijayaparthasarathi Vijayakumar
Published 2021-01-01

Design and synthesis of new 3-((7-chloroquinolin-4-yl)amino)thiazolidin-4-one analogs as Mycobacterium tuberculosis DNA gyrase inhibitors

by Preeti S. Salve, Prajakta Parchure, Lisel Araujo, Rohini S. Kavalapure, Sunil S. Jalalpure, Dharmarajan Sriram, Vagolu Siva Krishna, Madhu Rekha Estharla, Shankar G. Alegaon
Published 2021-01-01

Design, synthesis, and in vitro biological evaluation of dehydroaripiprazole derivatives as antituberculosis agents and molecular docking study

by B. Raja Sekhara Reddy, V. Pratap Reddy Gajulapalli, Estharla Madhu Rekha, Vagolu Siva Krishna, Dharmarajan Sriram, K Sudakar Babu, Eunha Kim
Published 2022-01-01

Thiazolotriazoles As Anti-infectives: Design, Synthesis, Biological Evaluation and In Silico Studies

by Umadevi Kizhakke Purakkel, Ganji Praveena, Valli Y. Madabhushi, Surender Singh Jadav, Reddy Shetty Prakasham, Saiprasad Goud Dasugari Varakala, Dharmarajan Sriram, Ewan W. Blanch, Subashani Maniam
Published 2024-02-01

Amsacrine Derivatives Selectively Inhibit Mycobacterial Topoisomerase I (TopA), Impair M. smegmatis Growth and Disturb Chromosome Replication

by Marcin J. Szafran, Marta Kołodziej, Patrycja Skut, Brahmam Medapi, Agnieszka Domagała, Damian Trojanowski, Jolanta Zakrzewska-Czerwińska, Jolanta Zakrzewska-Czerwińska, Dharmarajan Sriram, Dagmara Jakimowicz, Dagmara Jakimowicz
Published 2018-07-01