Salud intercultural desde la visión de las comunidades mapuche de Cañete y Tirúa

by Camila Pérez, Denisse Sepúlveda, Félix Cova, Gabriela Nazar
Published 2020-03-01

Small molecules to perform big roles: The search for Parkinson's and Huntington's disease therapeutics

by Rodrigo Pérez-Arancibia, Rodrigo Pérez-Arancibia, Marisol Cisternas-Olmedo, Marisol Cisternas-Olmedo, Marisol Cisternas-Olmedo, Denisse Sepúlveda, Denisse Sepúlveda, Denisse Sepúlveda, Paulina Troncoso-Escudero, Rene L. Vidal, Rene L. Vidal, Rene L. Vidal
Published 2023-01-01

Contribution of Autophagy-Lysosomal Pathway in the Exosomal Secretion of Alpha-Synuclein and Its Impact in the Progression of Parkinson’s Disease

by Denisse Sepúlveda, Denisse Sepúlveda, Denisse Sepúlveda, Marisol Cisternas-Olmedo, Marisol Cisternas-Olmedo, Marisol Cisternas-Olmedo, Javiera Arcos, Javiera Arcos, Javiera Arcos, Melissa Nassif, Melissa Nassif, René L. Vidal, René L. Vidal, René L. Vidal
Published 2022-02-01

On the Right Track to Treat Movement Disorders: Promising Therapeutic Approaches for Parkinson’s and Huntington’s Disease

by Paulina Troncoso-Escudero, Paulina Troncoso-Escudero, Paulina Troncoso-Escudero, Paulina Troncoso-Escudero, Denisse Sepulveda, Denisse Sepulveda, Denisse Sepulveda, Rodrigo Pérez-Arancibia, Rodrigo Pérez-Arancibia, Rodrigo Pérez-Arancibia, Alejandra V. Parra, Alejandra V. Parra, Alejandra V. Parra, Alejandra V. Parra, Javiera Arcos, Javiera Arcos, Javiera Arcos, Felipe Grunenwald, Felipe Grunenwald, Felipe Grunenwald, Rene L. Vidal, Rene L. Vidal, Rene L. Vidal
Published 2020-09-01

Insulin-like growth factor 2 and autophagy gene expression alteration arise as potential biomarkers in Parkinson’s disease

by Denisse Sepúlveda, Felipe Grunenwald, Alvaro Vidal, Paulina Troncoso-Escudero, Marisol Cisternas-Olmedo, Roque Villagra, Pedro Vergara, Carlos Aguilera, Melissa Nassif, Rene L. Vidal
Published 2022-02-01

IGF2 prevents dopaminergic neuronal loss and decreases intracellular alpha-synuclein accumulation in Parkinson’s disease models

by Javiera Arcos, Felipe Grunenwald, Denisse Sepulveda, Carolina Jerez, Valentina Urbina, Tomas Huerta, Paulina Troncoso-Escudero, Daniel Tirado, Angela Perez, Rodrigo Diaz-Espinoza, Esteban Nova, Ulrich Kubitscheck, Juan Eduardo Rodriguez-Gatica, Claudio Hetz, Jorge Toledo, Pablo Ahumada, Diego Rojas-Rivera, Elisa Martín-Montañez, María Garcia-Fernandez, René L. Vidal
Published 2023-12-01

Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response

by Estefanie Dufey, José Manuel Bravo-San Pedro, Cristian Eggers, Matías González-Quiroz, Hery Urra, Alfredo I. Sagredo, Denisse Sepulveda, Philippe Pihán, Amado Carreras-Sureda, Younis Hazari, Eduardo A. Sagredo, Daniela Gutierrez, Cristian Valls, Alexandra Papaioannou, Diego Acosta-Alvear, Gisela Campos, Pedro M. Domingos, Rémy Pedeux, Eric Chevet, Alejandra Alvarez, Patricio Godoy, Peter Walter, Alvaro Glavic, Guido Kroemer, Claudio Hetz
Published 2020-05-01

ER stress sensing mechanism: Putting off the brake on UPR transducers

by Rojas-Rivera, Diego, Rodriguez, Diego A., Sepulveda, Denisse, Hetz, Claudio
Published 2018