The Sphingosine-1-Phosphate Lyase (LegS2) Contributes to the Restriction of Legionella pneumophila in Murine Macrophages.

by Arwa Abu Khweek, Apurva Kanneganti, Denis C Guttridge D, Amal O Amer
Published 2016-01-01

NF-κB Functions in Tumor Initiation by Suppressing the Surveillance of Both Innate and Adaptive Immune Cells

by David J. Wang, Nivedita M. Ratnam, John C. Byrd, Denis C. Guttridge
Published 2014-10-01

Chemotherapy-induced muscle wasting: association with NF-κB and cancer cachexia

by Jeffrey S. Damrauer, Michael E. Stadler, Swarnali Acharyya, Albert S. Baldwin, Marion E. Couch, Denis C. Guttridge
Published 2018-06-01

Classical NF-κB Metabolically Reprograms Sarcoma Cells Through Regulation of Hexokinase 2

by Priya Londhe, Priya Londhe, Peter Y. Yu, Peter Y. Yu, Yuichi Ijiri, Yuichi Ijiri, Katherine J. Ladner, Katherine J. Ladner, Joelle M. Fenger, Cheryl London, Cheryl London, Peter J. Houghton, Denis C. Guttridge, Denis C. Guttridge
Published 2018-04-01

STAT3 activation in skeletal muscle links muscle wasting and the acute phase response in cancer cachexia.

by Andrea Bonetto, Tufan Aydogdu, Noelia Kunzevitzky, Denis C Guttridge, Sawsan Khuri, Leonidas G Koniaris, Teresa A Zimmers
Published 2011-01-01

A novel role for IkappaBzeta in the regulation of IFNgamma production.

by Raquel M Raices, Yashaswini Kannan, Vedavathi Bellamkonda-Athmaram, Sudarshan Seshadri, Huating Wang, Denis C Guttridge, Mark D Wewers
Published 2009-08-01

The impact of inflammation and acute phase activation in cancer cachexia

by Tyler P. Robinson, Tewfik Hamidi, Brittany Counts, Denis C. Guttridge, Michael C. Ostrowski, Teresa A. Zimmers, Teresa A. Zimmers, Leonidas G. Koniaris
Published 2023-10-01

NFκB signaling in alveolar rhabdomyosarcoma

by Megan M. Cleary, Atiya Mansoor, Teagan Settelmeyer, Yuichi Ijiri, Katherine J. Ladner, Matthew N. Svalina, Brian P. Rubin, Denis C. Guttridge, Charles Keller
Published 2017-09-01

Identification of circulating plasma ceramides as a potential sexually dimorphic biomarker of pancreatic cancer‐induced cachexia

by Jeffery M. Chakedis, Mary E. Dillhoff, Carl R. Schmidt, Priyani V. Rajasekera, David C. Evans, Terence M. Williams, Denis C. Guttridge, Erin E. Talbert
Published 2022-07-01

TNF inhibits Notch-1 in skeletal muscle cells by Ezh2 and DNA methylation mediated repression: implications in duchenne muscular dystrophy.

by Swarnali Acharyya, Sudarshana M Sharma, Alfred S Cheng, Katherine J Ladner, Wei He, William Kline, Huating Wang, Michael C Ostrowski, Tim H Huang, Denis C Guttridge
Published 2010-08-01

Optimization of a mouse model of pancreatic cancer to simulate the human phenotypes of metastasis and cachexia

by Victoria Spadafora, Benjamin R. Pryce, Alexander Oles, Erin E. Talbert, Martin Romeo, Silvia Vaena, Stefano Berto, Michael C. Ostrowski, David J. Wang, Denis C. Guttridge
Published 2024-04-01

MyoD Regulates Skeletal Muscle Oxidative Metabolism Cooperatively with Alternative NF-κB

by Jonathan Shintaku, Jennifer M. Peterson, Erin E. Talbert, Jin-Mo Gu, Katherine J. Ladner, Dustin R. Williams, Kambiz Mousavi, Ruoning Wang, Vittorio Sartorelli, Denis C. Guttridge
Published 2016-10-01

Systemic delivery of NEMO binding domain/IKKγ inhibitory peptide to young mdx mice improves dystrophic skeletal muscle histopathology

by Daniel P. Reay, Michele Yang, Jon F. Watchko, Molly Daood, Terrence L. O'Day, Khaleel K. Rehman, Denis C. Guttridge, Paul D. Robbins, Paula R. Clemens
Published 2011-09-01

Dietary Apigenin Exerts Immune-Regulatory Activity in Vivo by Reducing NF-κB Activity, Halting Leukocyte Infiltration and Restoring Normal Metabolic Function

by Horacio Cardenas, Daniel Arango, Courtney Nicholas, Silvia Duarte, Gerard J. Nuovo, Wei He, Oliver H. Voss, M. Elba Gonzalez-Mejia, Denis C. Guttridge, Erich Grotewold, Andrea I. Doseff
Published 2016-03-01

miR-133a function in the pathogenesis of dedifferentiated liposarcoma

by Peter Y. Yu, Gonzalo Lopez, Danielle Braggio, David Koller, Kate Lynn J. Bill, Bethany C. Prudner, Abbie Zewdu, James L. Chen, O. Hans Iwenofu, Dina Lev, Anne M. Strohecker, Joelle M. Fenger, Raphael E. Pollock, Denis C. Guttridge
Published 2018-06-01

Target specificity, in vivo pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma.

by Peter Y Yu, Heather L Gardner, Ryan Roberts, Hakan Cam, Seethalakshmi Hariharan, Ling Ren, Amy K LeBlanc, Hui Xiao, Jiayuh Lin, Denis C Guttridge, Xiaokui Mo, Chad E Bennett, Christopher C Coss, Yonghua Ling, Mitch A Phelps, Peter Houghton, Cheryl A London
Published 2017-01-01

Circulating monocyte chemoattractant protein‐1 (MCP‐1) is associated with cachexia in treatment‐naïve pancreatic cancer patients

by Erin E. Talbert, Heather L. Lewis, Matthew R. Farren, Mitchell L. Ramsey, Jeffery M. Chakedis, Priyani Rajasekera, Ericka Haverick, Angela Sarna, Mark Bloomston, Timothy M. Pawlik, Teresa A. Zimmers, Gregory B. Lesinski, Phil A. Hart, Mary E. Dillhoff, Carl R. Schmidt, Denis C. Guttridge
Published 2018-04-01

Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance

by Xueliang Gao, Yongxia Wu, Joel M. Chick, Andrea Abbott, Baishan Jiang, David J. Wang, Susana Comte-Walters, Roger H. Johnson, Nathaniel Oberholtzer, Michael I. Nishimura, Steven P. Gygi, Anand Mehta, Denis C. Guttridge, Lauren Ball, Shikhar Mehrotra, Piotr Sicinski, Xue-Zhong Yu, Haizhen Wang
Published 2023-04-01

NF-κB inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model

by Jennifer M. Peterson, David J. Wang, Vikram Shettigar, Steve R. Roof, Benjamin D. Canan, Nadine Bakkar, Jonathan Shintaku, Jin-Mo Gu, Sean C. Little, Nivedita M. Ratnam, Priya Londhe, Leina Lu, Christopher E. Gaw, Jennifer M. Petrosino, Sandya Liyanarachchi, Huating Wang, Paul M. L. Janssen, Jonathan P. Davis, Mark T. Ziolo, Sudarshana M. Sharma, Denis C. Guttridge
Published 2018-08-01