The opposite impact of Janus kinase inhibitor Ruxolitinib on the function of bone marrow mesenchymal stem cells and immune cells in acute GVHD recipients

by Defu Zeng
Published 2023-10-01

Regulation of GVHD and GVL Activity via PD-L1 Interaction With PD-1 and CD80

by Kaniel Cassady, Kaniel Cassady, Kaniel Cassady, Paul J. Martin, Paul J. Martin, Defu Zeng, Defu Zeng, Defu Zeng
Published 2018-12-01

Steroid-Refractory Gut Graft-Versus-Host Disease: What We Have Learned From Basic Immunology and Experimental Mouse Model

by Qingxiao Song, Qingxiao Song, Qingxiao Song, Ubaydah Nasri, Ubaydah Nasri, Defu Zeng, Defu Zeng
Published 2022-02-01

Retention of Donor T Cells in Lymphohematopoietic Tissue and Augmentation of Tissue PD-L1 Protection for Prevention of GVHD While Preserving GVL Activity

by Qingxiao Song, Qingxiao Song, Qingxiao Song, Ubaydah Nasri, Ubaydah Nasri, Ryotaro Nakamura, Paul J. Martin, Defu Zeng, Defu Zeng
Published 2022-05-01

Murine Models Provide New Insights Into Pathogenesis of Chronic Graft-Versus-Host Disease in Humans

by Qingxiao Song, Qingxiao Song, Qingxiao Song, Xiaohui Kong, Xiaohui Kong, Paul J. Martin, Paul J. Martin, Defu Zeng, Defu Zeng
Published 2021-09-01

Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease

by Ruishu Deng, Christian Hurtz, Qingxiao Song, Chanyu Yue, Gang Xiao, Hua Yu, Xiwei Wu, Markus Muschen, Stephen Forman, Paul J. Martin, Defu Zeng
Published 2017-10-01

microRNA-142 guards against autoimmunity by controlling Treg cell homeostasis and function.

by Wei-Le Wang, Ching Ouyang, Natalie M Graham, Yuankun Zhang, Kaniel Cassady, Estefany Y Reyes, Min Xiong, Alicia M Davis, Kathie Tang, Defu Zeng, Mark P Boldin
Published 2022-02-01

IL-22-dependent dysbiosis and mononuclear phagocyte depletion contribute to steroid-resistant gut graft-versus-host disease in mice

by Qingxiao Song, Xiaoning Wang, Xiwei Wu, Tae Hyuk Kang, Hanjun Qin, Dongchang Zhao, Robert R. Jenq, Marcel R. M. van den Brink, Arthur D. Riggs, Paul J. Martin, Yuan-Zhong Chen, Defu Zeng
Published 2021-02-01

Donor T cell STAT3 deficiency enables tissue PD-L1–dependent prevention of graft-versus-host disease while preserving graft-versus-leukemia activity

by Qinjian Li, Xiaoqi Wang, Qingxiao Song, Shijie Yang, Xiwei Wu, Dongyun Yang, Isabelle J. Marié, Hanjun Qin, Moqian Zheng, Ubaydah Nasri, Xiaohui Kong, Bixin Wang, Elizabeth Lizhar, Kaniel Cassady, Josh Tompkins, David Levy, Paul J. Martin, Xi Zhang, Defu Zeng
Published 2023-08-01