Anti-Viral Pattern Recognition Receptors as Therapeutic Targets

by Conor Hennessy, Declan P. McKernan
Published 2021-08-01

The Effect of Aggregated Alpha Synuclein on Synaptic and Axonal Proteins in Parkinson’s Disease—A Systematic Review

by Jennifer Murphy, Declan P. McKernan
Published 2022-08-01

Counting the Toll of Inflammation on Schizophrenia—A Potential Role for Toll-like Receptors

by Saahithh Redddi Patlola, Gary Donohoe, Declan P. McKernan
Published 2023-07-01

Microglial Phenotypes and Their Relationship to the Cannabinoid System: Therapeutic Implications for Parkinson’s Disease

by Rachel Kelly, Valerie Joers, Malú G. Tansey, Declan P. McKernan, Eilís Dowd
Published 2020-01-01

Time-Course of Alterations in the Endocannabinoid System after Viral-Mediated Overexpression of α-Synuclein in the Rat Brain

by Rachel Kelly, Alexis-Pierre Bemelmans, Charlène Joséphine, Emmanuel Brouillet, Declan P. McKernan, Eilís Dowd
Published 2022-01-01

The Small Molecule Alpha-Synuclein Aggregator, FN075, Enhances Alpha-Synuclein Pathology in Subclinical AAV Rat Models

by Rachel Kelly, Andrew G. Cairns, Jörgen Ådén, Fredrik Almqvist, Alexis-Pierre Bemelmans, Emmanuel Brouillet, Tommy Patton, Declan P. McKernan, Eilís Dowd
Published 2021-11-01

Toll-like receptor mRNA expression is selectively increased in the colonic mucosa of two animal models relevant to irritable bowel syndrome.

by Declan P McKernan, Aoife Nolan, Elizabeth K Brint, Siobhain M O'Mahony, Niall P Hyland, John F Cryan, Timothy G Dinan
Published 2009-12-01

A distinct profile of tryptophan metabolism along the kynurenine pathway downstream of Toll-like receptor activation in irritable bowel syndrome

by Gerard eClarke, Gerard eClarke, Gerard eClarke, Declan P McKernan, Gabor eGaszner, Eamonn M Quigley, Eamonn M Quigley, John F Cryan, John F Cryan, Timothy G Dinan, Timothy G Dinan
Published 2012-05-01

Corpus Callosum Microstructural Tract Integrity Relates to Longer Emotion Recognition Reaction Time in People with Schizophrenia

by Tom Burke, Christina Gleeson, Laurena Holleran, David Mothersill, Jessica Holland, Laura Costello, Ruán Kane, Declan P. McKernan, Derek W. Morris, John P. Kelly, Aiden P. Corvin, Brian P. Hallahan, Colm McDonald, Gary Donohoe
Published 2022-09-01

Early life stress, low-grade systemic inflammation and weaker suppression of the default mode network (DMN) during face processing in Schizophrenia

by Sinead King, David Mothersill, Laurena Holleran, Saahithh Redddi Patlola, Tom Burke, Ross McManus, Marcus Kenyon, Colm McDonald, Brian Hallahan, Aiden Corvin, Derek W. Morris, John P. Kelly, Declan P. McKernan, Gary Donohoe
Published 2023-06-01