A model for the evolution of extremely fragmented macronuclei in ciliates.

by David W Morgens, Kristen M Lindbergh, Marie Adachi, Ami Radunskaya, Andre R O Cavalcanti
Published 2013-01-01

A Two-tiered functional screen identifies herpesviral transcriptional modifiers and their essential domains.

by David W Morgens, Divya Nandakumar, Allison L Didychuk, Kevin J Yang, Britt A Glaunsinger
Published 2022-01-01

Protocol for performing pooled CRISPR-Cas9 loss-of-function screens

by Alyssa J. Mathiowetz, Melissa A. Roberts, David W. Morgens, James A. Olzmann, Zhipeng Li
Published 2023-06-01

Genome-wide interrogation of extracellular vesicle biology using barcoded miRNAs

by Albert Lu, Paulina Wawro, David W Morgens, Fernando Portela, Michael C Bassik, Suzanne R Pfeffer
Published 2018-12-01

Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway

by Michael M. Dubreuil, David W. Morgens, Kanji Okumoto, Masanori Honsho, Kévin Contrepois, Brittany Lee-McMullen, Gavin McAllister Traber, Ria S. Sood, Scott J. Dixon, Michael P. Snyder, Yukio Fujiki, Michael C. Bassik
Published 2020-02-01

The N 6-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity

by Masanori Yoshinaga, Kyuho Han, David W. Morgens, Takuro Horii, Ryosuke Kobayashi, Tatsuaki Tsuruyama, Fabian Hia, Shota Yasukura, Asako Kajiya, Ting Cai, Pedro H. C. Cruz, Alexis Vandenbon, Yutaka Suzuki, Yukio Kawahara, Izuho Hatada, Michael C. Bassik, Osamu Takeuchi
Published 2022-10-01

Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens

by David W. Morgens, Michael Wainberg, Evan A. Boyle, Oana Ursu, Carlos L. Araya, C. Kimberly Tsui, Michael S. Haney, Gaelen T. Hess, Kyuho Han, Edwin E. Jeng, Amy Li, Michael P. Snyder, William J. Greenleaf, Anshul Kundaje, Michael C. Bassik
Published 2017-05-01

Retro-2 protects cells from ricin toxicity by inhibiting ASNA1-mediated ER targeting and insertion of tail-anchored proteins

by David W Morgens, Charlene Chan, Andrew J Kane, Nicholas R Weir, Amy Li, Michael M Dubreuil, C Kimberly Tsui, Gaelen T Hess, Adam Lavertu, Kyuho Han, Nicole Polyakov, Jing Zhou, Emma L Handy, Philip Alabi, Amanda Dombroski, David Yao, Russ B Altman, Jason K Sello, Vladimir Denic, Michael C Bassik
Published 2019-11-01

Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements

by Josh Tycko, Michael Wainberg, Georgi K. Marinov, Oana Ursu, Gaelen T. Hess, Braeden K. Ego, Aradhana, Amy Li, Alisa Truong, Alexandro E. Trevino, Kaitlyn Spees, David Yao, Irene M. Kaplow, Peyton G. Greenside, David W. Morgens, Douglas H. Phanstiel, Michael P. Snyder, Lacramioara Bintu, William J. Greenleaf, Anshul Kundaje, Michael C. Bassik
Published 2019-09-01