Regulation of glucose metabolism in T cells; new insight into the role of Phosphoinositide 3-kinases

by David K Finlay, David K Finlay
Published 2012-08-01

Optimising NK cell metabolism to increase the efficacy of cancer immunotherapy

by Chloe Choi, David K. Finlay
Published 2021-06-01

Diverse Immunoregulatory Roles of Oxysterols—The Oxidized Cholesterol Metabolites

by Chloe Choi, David K. Finlay
Published 2020-09-01

Competition for nutrients and its role in controlling immune responses

by Nidhi Kedia-Mehta, David K. Finlay
Published 2019-05-01

Adenosine-mono-phosphate-activated protein kinase-independent effects of metformin in T cells.

by Marouan Zarrouk, David K Finlay, Marc Foretz, Benoit Viollet, Doreen A Cantrell
Published 2014-01-01

Metabolic but not transcriptional regulation by PKM2 is important for natural killer cell responses

by Jessica F Walls, Jeff J Subleski, Erika M Palmieri, Marieli Gonzalez-Cotto, Clair M Gardiner, Daniel W McVicar, David K Finlay
Published 2020-08-01

QUAS-R: An SLC1A5-mediated glutamine uptake assay with single-cell resolution reveals metabolic heterogeneity with immune populations

by Leonard R. Pelgrom, Gavin M. Davis, Simon O’Shaughnessy, Emilie J.M. Wezenberg, Sander I. Van Kasteren, David K. Finlay, Linda V. Sinclair
Published 2023-08-01

Glucose represses dendritic cell-induced T cell responses

by Simon J. Lawless, Nidhi Kedia-Mehta, Jessica F. Walls, Ryan McGarrigle, Orla Convery, Linda V. Sinclair, Maria N. Navarro, James Murray, David K. Finlay
Published 2017-05-01

Fatty acids are crucial to fuel NK cells upon acute retrovirus infection

by Simone Schimmer, Daniela Mittermüller, Daniela Mittermüller, Tanja Werner, Paul E. Görs, Sven W. Meckelmann, David K. Finlay, Ulf Dittmer, Elisabeth Littwitz-Salomon, Elisabeth Littwitz-Salomon
Published 2023-11-01

Akt and STAT5 mediate naïve human CD4+ T-cell early metabolic response to TCR stimulation

by Nicholas Jones, Emma E. Vincent, James G. Cronin, Silvia Panetti, Megan Chambers, Sean R. Holm, Sian E. Owens, Nigel J. Francis, David K. Finlay, Catherine A. Thornton
Published 2019-05-01

TGFβ drives NK cell metabolic dysfunction in human metastatic breast cancer

by Michael Conroy, John Kennedy, Karen Slattery, Elena Woods, Vanessa Zaiatz-Bittencourt, Sam Marks, Sonya Chew, Caitriona Goggin, Colm MacEochagain, Sophie Lucas, David K Finlay, Clair M Gardiner
Published 2021-02-01

Metabolic requirements of NK cells during the acute response against retroviral infection

by Elisabeth Littwitz-Salomon, Diana Moreira, Joe N. Frost, Chloe Choi, Kevin T. Liou, David K. Ahern, Simon O’Shaughnessy, Bernd Wagner, Christine A. Biron, Hal Drakesmith, Ulf Dittmer, David K. Finlay
Published 2021-09-01

Sugar or Fat?—Metabolic Requirements for Immunity to Viral Infections

by Hesham M. Shehata, Andrew J. Murphy, Man kit Sam Lee, Clair M. Gardiner, Suzanne M. Crowe, Suzanne M. Crowe, Shomyseh Sanjabi, David K. Finlay, Clovis Steve Palmer, Clovis Steve Palmer, Clovis Steve Palmer
Published 2017-10-01

Specific human cytomegalovirus signature detected in NK cell metabolic changes post vaccination

by Elena Woods, Vanessa Zaiatz-Bittencourt, Ciaran Bannan, Colm Bergin, David K. Finlay, Matthias Hoffmann, Anthony Brown, Bethany Turner, Shokouh Makvandi-Nejad, Ventzi Vassilev, Stefania Capone, Antonella Folgori, Tomáš Hanke, Eleanor Barnes, Lucy Dorrell, Clair M. Gardiner, PEACHI Consortium
Published 2021-09-01

The Circadian Clock Protein BMAL1 Acts as a Metabolic Sensor In Macrophages to Control the Production of Pro IL-1β

by George A. Timmons, Richard G. Carroll, James R. O’Siorain, Mariana P. Cervantes-Silva, Lauren E. Fagan, Shannon L. Cox, Eva Palsson-McDermott, David K. Finlay, Emma E. Vincent, Emma E. Vincent, Nicholas Jones, Annie M. Curtis
Published 2021-11-01

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

by Róisín M. Loftus, Nadine Assmann, Nidhi Kedia-Mehta, Katie L. O’Brien, Arianne Garcia, Conor Gillespie, Jens L. Hukelmann, Peter J. Oefner, Angus I. Lamond, Clair M. Gardiner, Katja Dettmer, Doreen A. Cantrell, Linda V. Sinclair, David K. Finlay
Published 2018-06-01

Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation

by Nicholas Jones, Julianna Blagih, Fabio Zani, April Rees, David G. Hill, Benjamin J. Jenkins, Caroline J. Bull, Diana Moreira, Azari I. M. Bantan, James G. Cronin, Daniele Avancini, Gareth W. Jones, David K. Finlay, Karen H. Vousden, Emma E. Vincent, Catherine A. Thornton
Published 2021-02-01

The circadian clock influences T cell responses to vaccination by regulating dendritic cell antigen processing

by Mariana P. Cervantes-Silva, Richard G. Carroll, Mieszko M. Wilk, Diana Moreira, Cloe A. Payet, James R. O’Siorain, Shannon L. Cox, Lauren E. Fagan, Paula A. Klavina, Yan He, Tabea Drewinski, Alan McGinley, Sharleen M. Buel, George A. Timmons, James O. Early, Roger J. S. Preston, Jennifer M. Hurley, David K. Finlay, Ingmar Schoen, F. Javier Sánchez-García, Kingston H. G. Mills, Annie M. Curtis
Published 2022-12-01

Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages

by Jennifer K. Dowling, Remsha Afzal, Linden J. Gearing, Mariana P. Cervantes-Silva, Stephanie Annett, Gavin M. Davis, Chiara De Santi, Nadine Assmann, Katja Dettmer, Daniel J. Gough, Glenn R. Bantug, Fidinny I. Hamid, Frances K. Nally, Conor P. Duffy, Aoife L. Gorman, Alex M. Liddicoat, Ed C. Lavelle, Christoph Hess, Peter J. Oefner, David K. Finlay, Gavin P. Davey, Tracy Robson, Annie M. Curtis, Paul J. Hertzog, Bryan R. G. Williams, Claire E. McCoy
Published 2021-03-01