Functional assessment of the NMDA receptor variant GluN2AR586K [version 1; referees: 1 approved, 2 approved with reservations]

by Katie F.M. Marwick, Peter Parker, Paul Skehel, Giles Hardingham, David J.A. Wyllie
Published 2017-03-01

Functional assessment of the NMDA receptor variant GluN2AR586K [version 2; referees: 1 approved, 2 approved with reservations]

by Katie F.M. Marwick, Peter Parker, Paul Skehel, Giles Hardingham, David J.A. Wyllie
Published 2017-04-01

Cellular and synaptic phenotypes lead to disrupted information processing in Fmr1-KO mouse layer 4 barrel cortex

by Aleksander P. F. Domanski, Sam A. Booker, David J. A. Wyllie, John T. R. Isaac, Peter C. Kind
Published 2019-10-01

Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity.

by Rickie Patani, Alastair Compston, Clare A Puddifoot, David J A Wyllie, Giles E Hardingham, Nicholas D Allen, Siddharthan Chandran
Published 2009-10-01

Postsynaptic GABABRs Inhibit L-Type Calcium Channels and Abolish Long-Term Potentiation in Hippocampal Somatostatin Interneurons

by Sam A. Booker, Desiree Loreth, Annabelle L. Gee, Masahiko Watanabe, Peter C. Kind, David J.A. Wyllie, Ákos Kulik, Imre Vida
Published 2018-01-01

Physiological normoxia and absence of EGF is required for the long-term propagation of anterior neural precursors from human pluripotent cells.

by Bilada Bilican, Matthew R Livesey, Ghazal Haghi, Jing Qiu, Karen Burr, Rick Siller, Giles E Hardingham, David J A Wyllie, Siddharthan Chandran
Published 2014-01-01

Hypothermic Preconditioning Reverses Tau Ontogenesis in Human Cortical Neurons and is Mimicked by Protein Phosphatase 2A Inhibition

by Nina M. Rzechorzek, Peter Connick, Matthew R. Livesey, Shyamanga Borooah, Rickie Patani, Karen Burr, David Story, David J.A. Wyllie, Giles E. Hardingham, Siddharthan Chandran
Published 2016-01-01

Altered dendritic spine function and integration in a mouse model of fragile X syndrome

by Sam A. Booker, Aleksander P. F. Domanski, Owen R. Dando, Adam D. Jackson, John T. R. Isaac, Giles E. Hardingham, David J. A. Wyllie, Peter C. Kind
Published 2019-10-01

Astrocytes mediate cell non-autonomous correction of aberrant firing in human FXS neurons

by Shreya Das Sharma, Bharath Kumar Reddy, Rakhi Pal, Tuula E. Ritakari, James D. Cooper, Bhuvaneish T. Selvaraj, Peter C. Kind, Siddharthan Chandran, David J.A. Wyllie, Sumantra Chattarji
Published 2023-04-01

Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction

by Emma M. Perkins, Karen Burr, Poulomi Banerjee, Arpan R. Mehta, Owen Dando, Bhuvaneish T. Selvaraj, Daumante Suminaite, Jyoti Nanda, Christopher M. Henstridge, Thomas H. Gillingwater, Giles E. Hardingham, David J. A. Wyllie, Siddharthan Chandran, Matthew R. Livesey
Published 2021-03-01

Input-Output Relationship of CA1 Pyramidal Neurons Reveals Intact Homeostatic Mechanisms in a Mouse Model of Fragile X Syndrome

by Sam A. Booker, Laura Simões de Oliveira, Natasha J. Anstey, Zrinko Kozic, Owen R. Dando, Adam D. Jackson, Paul S. Baxter, Lori L. Isom, Diane L. Sherman, Giles E. Hardingham, Peter J. Brophy, David J.A. Wyllie, Peter C. Kind
Published 2020-08-01

Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1

by Jamie McQueen, Tomás J Ryan, Sean McKay, Katie Marwick, Paul Baxter, Sarah M Carpanini, Thomas M Wishart, Thomas H Gillingwater, Jean C Manson, David J A Wyllie, Seth G N Grant, Barry W McColl, Noboru H Komiyama, Giles E Hardingham
Published 2017-07-01

Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns

by Shreya Das Sharma, Rakhi Pal, Bharath Kumar Reddy, Bhuvaneish T. Selvaraj, Nisha Raj, Krishna Kumar Samaga, Durga J. Srinivasan, Loren Ornelas, Dhruv Sareen, Matthew R. Livesey, Gary J. Bassell, Clive N. Svendsen, Peter C. Kind, Siddharthan Chandran, Sumantra Chattarji, David J. A. Wyllie
Published 2020-06-01

The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences

by Sean McKay, Tomás J. Ryan, Jamie McQueen, Tim Indersmitten, Katie F.M. Marwick, Philip Hasel, Maksym V. Kopanitsa, Paul S. Baxter, Marc-André Martel, Peter C. Kind, David J.A. Wyllie, Thomas J. O’Dell, Seth G.N. Grant, Giles E. Hardingham, Noboru H. Komiyama
Published 2018-10-01

Correction: Author Correction: Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism

by Philip Hasel, Owen Dando, Zoeb Jiwaji, Paul Baxter, Alison C. Todd, Samuel Heron, Nóra M. Márkus, Jamie McQueen, David W. Hampton, Megan Torvell, Sachin S. Tiwari, Sean McKay, Abel Eraso-Pichot, Antonio Zorzano, Roser Masgrau, Elena Galea, Siddharthan Chandran, David J. A. Wyllie, T. Ian Simpson, Giles E. Hardingham
Published 2018-02-01

Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism

by Philip Hasel, Owen Dando, Zoeb Jiwaji, Paul Baxter, Alison C. Todd, Samuel Heron, Nóra M. Márkus, Jamie McQueen, David W. Hampton, Megan Torvell, Sachin S. Tiwari, Sean McKay, Abel Eraso-Pichot, Antonio Zorzano, Roser Masgrau, Elena Galea, Siddharthan Chandran, David J. A. Wyllie, T. Ian Simpson, Giles E. Hardingham
Published 2017-05-01

Imbalance of flight–freeze responses and their cellular correlates in the Nlgn3 −/y rat model of autism

by Natasha J. Anstey, Vijayakumar Kapgal, Shashank Tiwari, Thomas C. Watson, Anna K. H. Toft, Owen R. Dando, Felicity H. Inkpen, Paul S. Baxter, Zrinko Kozić, Adam D. Jackson, Xin He, Mohammad Sarfaraz Nawaz, Aiman Kayenaat, Aditi Bhattacharya, David J. A. Wyllie, Sumantra Chattarji, Emma R. Wood, Oliver Hardt, Peter C. Kind
Published 2022-07-01

Enhanced hippocampal LTP but normal NMDA receptor and AMPA receptor function in a rat model of CDKL5 deficiency disorder

by Laura Simões de Oliveira, Heather E. O’Leary, Sarfaraz Nawaz, Rita Loureiro, Elizabeth C. Davenport, Paul Baxter, Susana R. Louros, Owen Dando, Emma Perkins, Julien Peltier, Matthias Trost, Emily K. Osterweil, Giles E. Hardingham, Michael A. Cousin, Sumantra Chattarji, Sam A. Booker, Tim A. Benke, David J. A Wyllie, Peter C. Kind
Published 2024-06-01

C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity

by Bhuvaneish T. Selvaraj, Matthew R. Livesey, Chen Zhao, Jenna M. Gregory, Owain T. James, Elaine M. Cleary, Amit K. Chouhan, Angus B. Gane, Emma M. Perkins, Owen Dando, Simon G. Lillico, Youn-Bok Lee, Agnes L. Nishimura, Urjana Poreci, Sai Thankamony, Meryll Pray, Navneet A. Vasistha, Dario Magnani, Shyamanga Borooah, Karen Burr, David Story, Alexander McCampbell, Christopher E. Shaw, Peter C. Kind, Timothy J. Aitman, C. Bruce A. Whitelaw, Ian Wilmut, Colin Smith, Gareth B. Miles, Giles E. Hardingham, David J. A. Wyllie, Siddharthan Chandran
Published 2018-01-01