A protocol for detecting elemental calcium signals (Ca2+ puffs) in mammalian cells using total internal reflection fluorescence microscopy

by Vikas Arige, Scott M. Emrich, Ryan E. Yoast, Mohamed Trebak, David I. Yule
Published 2021-09-01

Simulation of Calcium Dynamics in Realistic Three-Dimensional Domains

by James Sneyd, John Rugis, Shan Su, Vinod Suresh, Amanda M. Wahl, David I. Yule
Published 2022-10-01

Modulation of cytosolic calcium signaling by protein kinase A-mediated phosphorylation of inositol 1,4,5-trisphosphate receptors

by STEPHEN V STRAUB, LARRY E WAGNER II, JASON I.E BRUCE, DAVID I YULE
Published 2004-01-01

Highly localized intracellular Ca2+ signals promote optimal salivary gland fluid secretion

by Takahiro Takano, Amanda M Wahl, Kai-Ting Huang, Takanori Narita, John Rugis, James Sneyd, David I Yule
Published 2021-07-01

Regulation of store-operated Ca2+ entry by IP3 receptors independent of their ability to release Ca2+

by Pragnya Chakraborty, Bipan Kumar Deb, Vikas Arige, Thasneem Musthafa, Sundeep Malik, David I Yule, Colin W Taylor, Gaiti Hasan
Published 2023-07-01

Evidence That Calcium Entry Into Calcium-Transporting Dental Enamel Cells Is Regulated by Cholecystokinin, Acetylcholine and ATP

by Meerim K. Nurbaeva, Miriam Eckstein, Arun Devotta, Jean-Pierre Saint-Jeannet, David I. Yule, Michael J. Hubbard, Rodrigo S. Lacruz
Published 2018-07-01

Capture at the ER-mitochondrial contacts licenses IP3 receptors to stimulate local Ca2+ transfer and oxidative metabolism

by Máté Katona, Ádám Bartók, Zuzana Nichtova, György Csordás, Elena Berezhnaya, David Weaver, Arijita Ghosh, Péter Várnai, David I. Yule, György Hajnóczky
Published 2022-11-01

Conformational motions and ligand-binding underlying gating and regulation in IP3R channel

by Guizhen Fan, Mariah R. Baker, Lara E. Terry, Vikas Arige, Muyuan Chen, Alexander B. Seryshev, Matthew L. Baker, Steven J. Ludtke, David I. Yule, Irina I. Serysheva
Published 2022-11-01

Missense mutations in inositol 1,4,5-trisphosphate receptor type 3 result in leaky Ca2+ channels and activation of store-operated Ca2+ entry

by Lara E. Terry, Vikas Arige, Julika Neumann, Amanda M. Wahl, Taylor R. Knebel, James W. Chaffer, Sundeep Malik, Adrian Liston, Stephanie Humblet-Baron, Geert Bultynck, David I. Yule
Published 2022-12-01

The native ORAI channel trio underlies the diversity of Ca2+ signaling events

by Ryan E. Yoast, Scott M. Emrich, Xuexin Zhang, Ping Xin, Martin T. Johnson, Adam J. Fike, Vonn Walter, Nadine Hempel, David I. Yule, James Sneyd, Donald L. Gill, Mohamed Trebak
Published 2020-05-01

IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer

by Adam Bartok, David Weaver, Tünde Golenár, Zuzana Nichtova, Máté Katona, Száva Bánsághi, Kamil J. Alzayady, V. Kaye Thomas, Hideaki Ando, Katsuhiko Mikoshiba, Suresh K. Joseph, David I. Yule, György Csordás, György Hajnóczky
Published 2019-08-01

Two-pore channel-2 and inositol trisphosphate receptors coordinate Ca2+ signals between lysosomes and the endoplasmic reticulum

by Yu Yuan, Vikas Arige, Ryo Saito, Qianru Mu, Gabriela C. Brailoiu, Gustavo J.S. Pereira, Stephen R. Bolsover, Marco Keller, Franz Bracher, Christian Grimm, Eugen Brailoiu, Jonathan S. Marchant, David I. Yule, Sandip Patel
Published 2024-01-01

Alpha-helical destabilization of the Bcl-2-BH4-domain peptide abolishes its ability to inhibit the IP3 receptor.

by Giovanni Monaco, Elke Decrock, Koen Nuyts, Larry E Wagner, Tomas Luyten, Sergei V Strelkov, Ludwig Missiaen, Wim M De Borggraeve, Luc Leybaert, David I Yule, Humbert De Smedt, Jan B Parys, Geert Bultynck
Published 2013-01-01

Pancreas-specific CHRM3 activation causes pancreatitis in mice

by Jianhua Wan, Jiale Wang, Larry E. Wagner II, Oliver H. Wang, Fu Gui, Jiaxiang Chen, Xiaohui Zhu, Ashley N. Haddock, Brandy H. Edenfield, Brian Haight, Debabrata Mukhopadhyay, Ying Wang, David I. Yule, Yan Bi, Baoan Ji
Published 2021-09-01

Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomes

by Yu Yuan, Dawid Jaślan, Taufiq Rahman, Stephen R. Bolsover, Vikas Arige, Larry E. Wagner, Carla Abrahamian, Rachel Tang, Marco Keller, Jonas Hartmann, Anna S. Rosato, Eva-Maria Weiden, Franz Bracher, David I. Yule, Christian Grimm, Sandip Patel
Published 2022-08-01

Platelet olfactory receptor activation limits platelet reactivity and growth of aortic aneurysms

by Craig N. Morrell, Doran Mix, Anu Aggarwal, Rohan Bhandari, Matthew Godwin, Phillip Owens III, Sean P. Lyden, Adam Doyle, Krystin Krauel, Matthew T. Rondina, Amy Mohan, Charles J. Lowenstein, Sharon Shim, Shaun Stauffer, Vara Prasad Josyula, Sara K. Ture, David I. Yule, Larry E. Wagner III, John M. Ashton, Ayman Elbadawi, Scott J. Cameron
Published 2022-05-01