Mass cytometry immunostaining protocol for multiplexing clinical samples

by Ramy Gadalla, Giselle M. Boukhaled, David G. Brooks, Ben X. Wang
Published 2022-09-01

Prevention of CD8 T Cell Deletion during Chronic Viral Infection

by David G. Brooks, Antoinette Tishon, Michael B. A. Oldstone, Dorian B. McGavern
Published 2021-06-01

Overcoming CD4 Th1 Cell Fate Restrictions to Sustain Antiviral CD8 T Cells and Control Persistent Virus Infection

by Laura M. Snell, Ivan Osokine, Douglas H. Yamada, Justin Rafael De la Fuente, Heidi J. Elsaesser, David G. Brooks
Published 2016-09-01

Statin Pharmacogenomics: Opportunities to Improve Patient Outcomes and Healthcare Costs with Genetic Testing

by William J. Canestaro, David G. Brooks, Donald Chaplin, Niteesh K. Choudhry, Elizabeth Lawler, Lori Martell, Troyen Brennan, E. Robert Wassman
Published 2012-10-01

Validation of CyTOF Against Flow Cytometry for Immunological Studies and Monitoring of Human Cancer Clinical Trials

by Ramy Gadalla, Babak Noamani, Bethany L. MacLeod, Russell J. Dickson, Mengdi Guo, Wenxi Xu, Sabelo Lukhele, Heidi J. Elsaesser, Albiruni R. Abdul Razak, Naoto Hirano, Naoto Hirano, Tracy L. McGaha, Tracy L. McGaha, Ben Wang, Marcus Butler, Cynthia J. Guidos, Cynthia J. Guidos, Pam S. Ohashi, Pam S. Ohashi, Lillian L. Siu, David G. Brooks, David G. Brooks
Published 2019-05-01

Rapid detection of Mycobacterium tuberculosis by recombinase polymerase amplification.

by David S Boyle, Ruth McNerney, Hwee Teng Low, Brandon Troy Leader, Ailyn C Pérez-Osorio, Jessica C Meyer, Denise M O'Sullivan, David G Brooks, Olaf Piepenburg, Matthew S Forrest
Published 2014-01-01

Molecular, metabolic, and functional CD4 T cell paralysis in the lymph node impedes tumor control

by Mengdi Guo, Diala Abd-Rabbo, Bruna C. Bertol, Madeleine Carew, Sabelo Lukhele, Laura M. Snell, Wenxi Xu, Giselle M. Boukhaled, Heidi Elsaesser, Marie Jo Halaby, Naoto Hirano, Tracy L. McGaha, David G. Brooks
Published 2023-09-01

Type I and Type II Interferon Coordinately Regulate Suppressive Dendritic Cell Fate and Function during Viral Persistence.

by Cameron R Cunningham, Ameya Champhekar, Michael V Tullius, Barbara Jane Dillon, Anjie Zhen, Justin Rafael de la Fuente, Jonathan Herskovitz, Heidi Elsaesser, Laura M Snell, Elizabeth B Wilson, Juan Carlos de la Torre, Scott G Kitchen, Marcus A Horwitz, Steven J Bensinger, Stephen T Smale, David G Brooks
Published 2016-01-01

Translational randomized phase II trial of cabozantinib in combination with nivolumab in advanced, recurrent, or metastatic endometrial cancer

by John Wright, Stephanie Lheureux, Ilaria Colombo, Ramy Gadalla, Pamela S Ohashi, Xuan Li, Lisa Wang, Matthew S Block, David G Brooks, Andrea Jewell, Carolyn McCourt, Eugenia Girda, Sarah Temkin, Gini F Fleming, Linda Duska, Daniela E Matei, Panagiotis A Konstantinopoulos, Ben X Wang, Stephanie L Gaillard, Michael McHale, Floor J Backes, Theresa L Werner, Siobhan Kehoe, Rachel Wildman, Shirin Soleimani, Scott Lien, Trevor Pugh
Published 2022-03-01

Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity

by S. Y. Cindy Yang, Scott C. Lien, Ben X. Wang, Derek L. Clouthier, Youstina Hanna, Iulia Cirlan, Kelsey Zhu, Jeffrey P. Bruce, Samah El Ghamrasni, Marco A. J. Iafolla, Marc Oliva, Aaron R. Hansen, Anna Spreafico, Philippe L. Bedard, Stephanie Lheureux, Albiruni Razak, Vanessa Speers, Hal K. Berman, Alexey Aleshin, Benjamin Haibe-Kains, David G. Brooks, Tracy L. McGaha, Marcus O. Butler, Scott V. Bratman, Pamela S. Ohashi, Lillian L. Siu, Trevor J. Pugh
Published 2021-08-01

An interim report on the investigator-initiated phase 2 study of pembrolizumab immunological response evaluation (INSPIRE)

by Derek L. Clouthier, Scott C. Lien, S. Y. Cindy Yang, Linh T. Nguyen, Venkata S. K. Manem, Diana Gray, Michael Ryczko, Albiruni R. A. Razak, Jeremy Lewin, Stephanie Lheureux, Ilaria Colombo, Philippe L. Bedard, David Cescon, Anna Spreafico, Marcus O. Butler, Aaron R. Hansen, Raymond W. Jang, Sangeet Ghai, Ilan Weinreb, Valentin Sotov, Ramy Gadalla, Babak Noamani, Mengdi Guo, Sawako Elston, Amanda Giesler, Sevan Hakgor, Haiyan Jiang, Tracy McGaha, David G. Brooks, Benjamin Haibe-Kains, Trevor J. Pugh, Pamela S. Ohashi, Lillian L. Siu
Published 2019-03-01