Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics

by Gillian P. McHugo, Michael J. Dover, David E. MacHugh
Published 2019-12-01

Alveolar Macrophage Chromatin Is Modified to Orchestrate Host Response to Mycobacterium bovis Infection

by Thomas J. Hall, Douglas Vernimmen, John A. Browne, Michael P. Mullen, Stephen V. Gordon, Stephen V. Gordon, David E. MacHugh, David E. MacHugh, Alan M. O’Doherty
Published 2020-02-01

Transcriptomic Analysis of Ovine Hepatic Lymph Node Following Fasciola hepatica Infection – Inhibition of NK Cell and IgE-Mediated Signaling

by Amalia Naranjo-Lucena, Carolina N. Correia, Verónica Molina-Hernández, Álvaro Martínez-Moreno, John A. Browne, José Pérez, David E. MacHugh, David E. MacHugh, Grace Mulcahy, Grace Mulcahy
Published 2021-05-01

Timing of Transcriptomic Peripheral Blood Mononuclear Cell Responses of Sheep to Fasciola hepatica Infection Differs From Those of Cattle, Reflecting Different Disease Phenotypes

by Dagmara A. Niedziela, Amalia Naranjo-Lucena, Verónica Molina-Hernández, John A. Browne, Álvaro Martínez-Moreno, José Pérez, David E. MacHugh, David E. MacHugh, Grace Mulcahy, Grace Mulcahy
Published 2021-09-01

Fasciola hepatica Infection in Cattle: Analyzing Responses of Peripheral Blood Mononuclear Cells (PBMC) Using a Transcriptomics Approach

by Andres Garcia-Campos, Carolina N. Correia, Amalia Naranjo-Lucena, Laura Garza-Cuartero, Gabriella Farries, John A. Browne, David E. MacHugh, David E. MacHugh, Grace Mulcahy, Grace Mulcahy
Published 2019-08-01

Comparative functional genomics and the bovine macrophage response to strains of the Mycobacterium genus

by Kévin eRue-Albrecht, David A. Magee, David A. Magee, Kate E. Killick, Kate E. Killick, Nicolas C. Nalpas, Stephen V. Gordon, Stephen V. Gordon, David E. Machugh, David E. Machugh
Published 2014-11-01

RNA Sequencing (RNA-Seq) Reveals Extremely Low Levels of Reticulocyte-Derived Globin Gene Transcripts in Peripheral Blood From Horses (Equus caballus) and Cattle (Bos taurus)

by Carolina N. Correia, Kirsten E. McLoughlin, Nicolas C. Nalpas, David A. Magee, John A. Browne, Kevin Rue-Albrecht, Stephen V. Gordon, Stephen V. Gordon, David E. MacHugh, David E. MacHugh
Published 2018-08-01

Genomic Characterisation of the Indigenous Irish Kerry Cattle Breed

by Sam Browett, Gillian McHugo, Ian W. Richardson, David A. Magee, Stephen D. E. Park, Alan G. Fahey, John F. Kearney, Carolina N. Correia, Imtiaz A. S. Randhawa, David E. MacHugh, David E. MacHugh
Published 2018-02-01

Expression Quantitative Trait Loci in Equine Skeletal Muscle Reveals Heritable Variation in Metabolism and the Training Responsive Transcriptome

by Gabriella Farries, Kenneth Bryan, Charlotte L. McGivney, Paul A. McGettigan, Katie F. Gough, John A. Browne, David E. MacHugh, David E. MacHugh, Lisa Michelle Katz, Emmeline W. Hill, Emmeline W. Hill
Published 2019-11-01

The Identification of Circulating MiRNA in Bovine Serum and Their Potential as Novel Biomarkers of Early Mycobacterium avium subsp paratuberculosis Infection.

by Damien Farrell, Ronan G Shaughnessy, Louise Britton, David E MacHugh, Bryan Markey, Stephen V Gordon
Published 2015-01-01

Transcriptome Profiling of Developing Ovine Fat Tail Tissue Reveals an Important Role for MTFP1 in Regulation of Adipogenesis

by Jiangang Han, Jiangang Han, Sijia Ma, Benmeng Liang, Benmeng Liang, Tianyou Bai, Tianyou Bai, Yuhetian Zhao, Yuhetian Zhao, Yuehui Ma, Yuehui Ma, David E. MacHugh, David E. MacHugh, Lina Ma, Lin Jiang, Lin Jiang
Published 2022-03-01

Preferential differential gene expression within the WC1.1+ γδ T cell compartment in cattle naturally infected with Mycobacterium bovis

by Sajad A. Bhat, Sajad A. Bhat, Sajad A. Bhat, Mahmoud Elnaggar, Thomas J. Hall, Gillian P. McHugo, Cian Reid, David E. MacHugh, David E. MacHugh, Kieran G. Meade, Kieran G. Meade, Kieran G. Meade
Published 2023-10-01

A genome scan for positive selection in thoroughbred horses.

by Jingjing Gu, Nick Orr, Stephen D Park, Lisa M Katz, Galina Sulimova, David E MacHugh, Emmeline W Hill
Published 2009-06-01

RNA-Seq Transcriptome Analysis of Peripheral Blood From Cattle Infected With Mycobacterium bovis Across an Experimental Time Course

by Kirsten E. McLoughlin, Carolina N. Correia, John A. Browne, David A. Magee, Nicolas C. Nalpas, Kevin Rue-Albrecht, Adam O. Whelan, Bernardo Villarreal-Ramos, H. Martin Vordermeier, Eamonn Gormley, Stephen V. Gordon, Stephen V. Gordon, David E. MacHugh, David E. MacHugh
Published 2021-05-01

A Population Genomics Analysis of the Native Irish Galway Sheep Breed

by Gillian P. McHugo, Sam Browett, Imtiaz A. S. Randhawa, Dawn J. Howard, Michael P. Mullen, Ian W. Richardson, Stephen D. E. Park, David A. Magee, Erik Scraggs, Michael J. Dover, Carolina N. Correia, James P. Hanrahan, David E. MacHugh, David E. MacHugh
Published 2019-10-01

Selection in Australian Thoroughbred horses acts on a locus associated with early two-year old speed.

by Haige Han, Beatrice A McGivney, Gabriella Farries, Lisa M Katz, David E MacHugh, Imtiaz A S Randhawa, Emmeline W Hill
Published 2020-01-01

Selection signatures for local and regional adaptation in Chinese Mongolian horse breeds reveal candidate genes for hoof health

by Haige Han, Imtiaz A. S. Randhawa, David E. MacHugh, Beatrice A. McGivney, Lisa M. Katz, Manglai Dugarjaviin, Emmeline W. Hill
Published 2023-01-01

Analysis of the bovine monocyte-derived macrophage response to Mycobacterium avium subspecies paratuberculosis infection using RNA-seq

by Maura E Casey, Maura E Casey, Kieran G. Meade, Nicolas C Nalpas, Maria eTaraktsoglou, John A Browne, Kate E Killick, Kate E Killick, Stephen David Edward Park, Stephen David Edward Park, Eamonn eGormley, Karsten eHokamp, David A Magee, David A Magee, David E Machugh, David E Machugh
Published 2015-02-01

Transcriptomics analysis of the bovine endometrium during the perioestrus period.

by Mohammed A Alfattah, Carolina N Correia, John A Browne, Paul A McGettigan, Katarzyna Pluta, Stephen D Carrington, David E MacHugh, Jane A Irwin
Published 2024-01-01

A sequence polymorphism in MSTN predicts sprinting ability and racing stamina in thoroughbred horses.

by Emmeline W Hill, Jingjing Gu, Suzanne S Eivers, Rita G Fonseca, Beatrice A McGivney, Preethi Govindarajan, Nick Orr, Lisa M Katz, David E MacHugh
Published 2010-01-01