Determining the Effects of Differential Expression of GRKs and β-arrestins on CLR-RAMP Agonist Bias

by Abigail Pearce, Theo Redfern-Nichols, Matthew Harris, David R. Poyner, Mark Wigglesworth, Graham Ladds
Published 2022-03-01

Functional solubilization of the β2-adrenoceptor using diisobutylene maleic acid

by Clare.R. Harwood, David A. Sykes, Bradley L. Hoare, Franziska M. Heydenreich, Romez Uddin, David R. Poyner, Stephen J. Briddon, D.B. Veprintsev
Published 2021-12-01

The Role of ICL1 and H8 in Class B1 GPCRs; Implications for Receptor Activation

by Ian Winfield, Kerry Barkan, Sarah Routledge, Sarah Routledge, Nathan J. Robertson, Matthew Harris, Ali Jazayeri, John Simms, Christopher A. Reynolds, David R. Poyner, Graham Ladds
Published 2022-01-01

CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells

by Ashley J. Clark, Niamh Mullooly, Dewi Safitri, Matthew Harris, Tessa de Vries, Antoinette MaassenVanDenBrink, David R. Poyner, Davide Gianni, Mark Wigglesworth, Graham Ladds
Published 2021-06-01

G-protein coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent

by Mohammed Jamshad, Jack Charlton, Yu‑Pin Lin, Sarah J. Routledge, Zharain Bawa, Timothy J. Knowles, Michael Overduin, Niek Dekker, Tim R. Dafforn, Roslyn M. Bill, David R. Poyner, Mark Wheatley
Published 2015-04-01