Sebaceous carcinoma of the eyelid in a patient with Muir-Torre syndrome treated with pembrolizumab: A case report

by Ahmed Abdalla, Gabriel Roman Souza, Daruka Mahadevan
Published 2022-06-01

Expression Levels of RAD51 Inversely Correlate with Survival of Glioblastoma Patients

by Christopher Morrison, Eric Weterings, Daruka Mahadevan, Abhay Sanan, Martin Weinand, Baldassarre Stea
Published 2021-10-01

A Comparative Analysis of Tumors and Plasma Circulating Tumor DNA in 145 Advanced Cancer Patients Annotated by 3 Core Cellular Processes

by Kristian Larson, Radhamani Kannaiyan, Ritu Pandey, Yuliang Chen, Hani M. Babiker, Daruka Mahadevan
Published 2020-03-01

Using cfDNA and ctDNA as Oncologic Markers: A Path to Clinical Validation

by Jonathan Dao, Patrick J. Conway, Baskaran Subramani, Devi Meyyappan, Sammy Russell, Daruka Mahadevan
Published 2023-08-01

<i>TP53</i> Mutations as a Driver of Metastasis Signaling in Advanced Cancer Patients

by Ritu Pandey, Nathan Johnson, Laurence Cooke, Benny Johnson, Yuliang Chen, Manjari Pandey, Jason Chandler, Daruka Mahadevan
Published 2021-02-01

Rare Tumor-Normal Matched Whole Exome Sequencing Identifies Novel Genomic Pathogenic Germline and Somatic Aberrations

by Ryan Sprissler, Bryce Perkins, Laurel Johnstone, Hani M. Babiker, Pavani Chalasani, Branden Lau, Michael Hammer, Daruka Mahadevan
Published 2020-06-01

Gene Expression Patterns Associated with Survival in Glioblastoma

by Christopher Morrison, Eric Weterings, Nicholas Gravbrot, Michael Hammer, Martin Weinand, Abhay Sanan, Ritu Pandey, Daruka Mahadevan, Baldassarre Stea
Published 2024-03-01

Aurkin-A, a TPX2-aurora a small molecule inhibitor disrupts Alisertib-induced polyploidy in aggressive diffuse large B cell lymphoma

by Patrick J. Conway, Bárbara De La Peña Avalos, Jonathan Dao, Sebastian Montagnino, Dmytro Kovalskyy, Eloise Dray, Daruka Mahadevan
Published 2024-09-01

PD-1-Associated Gene Expression Signature of Neoadjuvant Trastuzumab-Treated Tumors Correlates with Patient Survival in HER2-Positive Breast Cancer

by William P. D. Hendricks, Natalia Briones, Rebecca F. Halperin, Salvatore Facista, Paul R. Heaton, Daruka Mahadevan, Suwon Kim
Published 2019-10-01

DNA methylation biomarkers discovered in silico detect cancer in liquid biopsies from non-small cell lung cancer patients

by Lukas Vrba, Marc M. Oshiro, Samuel S. Kim, Linda L. Garland, Crystal Placencia, Daruka Mahadevan, Mark A. Nelson, Bernard W. Futscher
Published 2020-04-01

Alisertib added to rituximab and vincristine is synthetic lethal and potentially curative in mice with aggressive DLBCL co-overexpressing MYC and BCL2.

by Daruka Mahadevan, Carla Morales, Laurence S Cooke, Ann Manziello, David W Mount, Daniel O Persky, Richard I Fisher, Thomas P Miller, Wenqing Qi
Published 2014-01-01

ERBB2 (HER2) amplifications and co-occurring KRAS alterations in the circulating cell-free DNA of pancreatic ductal adenocarcinoma patients and response to HER2 inhibition

by Afsaneh Barzi, Caroline M. Weipert, Carin R. Espenschied, Victoria M. Raymond, Andrea Wang-Gillam, Mohammad Amin Nezami, Eva J. Gordon, Daruka Mahadevan, Kabir Mody
Published 2024-02-01

Safety and efficacy of the tumor-selective adenovirus enadenotucirev, in combination with nivolumab, in patients with advanced/metastatic epithelial cancer: a phase I clinical tria...

by Daruka Mahadevan, Tom Lillie, Wael Harb, Jordan Berlin, Mark Powell, Marwan Fakih, Lee Rosen, David Krige, Minesh Patel, Hani Babiker, Jo Carter, Chris Cox, Lola Parfitt
Published 2023-04-01

Phase I study of samalizumab in chronic lymphocytic leukemia and multiple myeloma: blockade of the immune checkpoint CD200

by Daruka Mahadevan, Mark C. Lanasa, Charles Farber, Manjari Pandey, Maria Whelden, Susan J. Faas, Terrie Ulery, Anjli Kukreja, Lan Li, Camille L. Bedrosian, Xiaoping Zhang, Leonard T. Heffner
Published 2019-08-01

479 AGEN1181, an Fc-enhanced anti-CTLA-4 antibody, alone and in combination with balstilimab (anti-PD-1) in patients with advanced solid tumors: Initial phase I results

by Andrea Bullock, Justin Moser, Daruka Mahadevan, Michael Gordon, Przemyslaw Twardowski, Apostolia Tsimberidou, Breelyn Wilky, Waldo Ortuzar Feliu, Anthony El-Khoueiry, Steven O’Day, Bruno Bockorny, Katherine Rosenthal
Published 2021-11-01

Phase I study of single-agent CC-292, a highly selective Bruton’s tyrosine kinase inhibitor, in relapsed/refractory chronic lymphocytic leukemia

by Jennifer R. Brown, Wael A. Harb, Brian T. Hill, Janice Gabrilove, Jeff P. Sharman, Marshall T. Schreeder, Paul M. Barr, James M. Foran, Thomas P. Miller, Jan A. Burger, Kevin R. Kelly, Daruka Mahadevan, Shuo Ma, Yan Li, Daniel W. Pierce, Evelyn Barnett, Jeffrey Marine, Monika Miranda, Ada Azaryan, Xujie Yu, Pilar Nava-Parada, Jay Mei, Thomas J. Kipps
Published 2016-07-01

AXL-initiated paracrine activation of pSTAT3 enhances mesenchymal and vasculogenic supportive features of tumor-associated macrophages

by Chia-Nung Hung, Meizhen Chen, Daniel T. DeArmond, Cheryl H.-L. Chiu, Catherine A. Limboy, Xi Tan, Meena Kusi, Chih-Wei Chou, Li-Ling Lin, Zhao Zhang, Chiou-Miin Wang, Chun-Liang Chen, Kohzoh Mitsuya, Pawel A. Osmulski, Maria E. Gaczynska, Nameer B. Kirma, Ratna K. Vadlamudi, Don L. Gibbons, Steve Warner, Andrew J. Brenner, Daruka Mahadevan, Joel E. Michalek, Tim H.-M. Huang, Josephine A. Taverna
Published 2023-09-01