Prime Editor 3 Mediated Beta-Thalassemia Mutations of the <i>HBB</i> Gene in Human Erythroid Progenitor Cells

by Haokun Zhang, Qinlinglan Zhou, Hongyan Chen, Daru Lu
Published 2022-04-01

Correction of Beta-Thalassemia IVS-II-654 Mutation in a Mouse Model Using Prime Editing

by Haokun Zhang, Ruilin Sun, Jian Fei, Hongyan Chen, Daru Lu
Published 2022-05-01

Prudently conduct the engineering and synthesis of the SARS-CoV-2 virus

by Peng Gao, Shiwen Ma, Daru Lu, Carl Mitcham, Yijia Jing, Guoyu Wang
Published 2020-06-01

Integrative preimplantation genetic testing analysis for a Chinese family with hereditary spherocytosis caused by a novel splicing variant of SPTB

by Yafei Tian, Yao Wang, Jingmin Yang, Jingmin Yang, Jingmin Yang, Pengfei Gao, Pengfei Gao, Hui Xu, Yiming Wu, Mengru Li, Hongyan Chen, Daru Lu, Daru Lu, Hongli Yan
Published 2023-09-01

Atoh8, a bHLH transcription factor, is required for the development of retina and skeletal muscle in zebrafish.

by Jihua Yao, Jingyao Zhou, Qiaoling Liu, Daru Lu, Lu Wang, Xiaojing Qiao, William Jia
Published 2010-06-01

Development of a new genetic reference material system based on Saccharomyces cerevisiae cells

by Xin He, Jiaqi Ding, Zhenhua Xu, Na Li, Jingmin Yang, Hongyan Chen, Daru Lu
Published 2021-03-01

The Loss-Function of <i>KNL1</i> Causes Oligospermia and Asthenospermia in Mice by Affecting the Assembly and Separation of the Spindle through Flow Cytometry and Immunofluorescenc...

by Yuwei Zhao, Jingmin Yang, Daru Lu, Yijian Zhu, Kai Liao, Yafei Tian, Rui Yin
Published 2023-02-01

Intra-Monozygotic Twin Pair Discordance and Longitudinal Variation of Whole-Genome Scale DNA Methylation in Adults.

by Na Zhang, Shumin Zhao, Su-Hua Zhang, Jinzhong Chen, Daru Lu, Min Shen, Chengtao Li
Published 2015-01-01

Selective histonedeacetylase inhibitor M344 intervenes in HIV-1 latency through increasing histone acetylation and activation of NF-kappaB.

by Hao Ying, Yuhao Zhang, Xin Zhou, Xiying Qu, Pengfei Wang, Sijie Liu, Daru Lu, Huanzhang Zhu
Published 2012-01-01

Multi-Omics Analysis in β-Thalassemia Using an <i>HBB</i> Gene-Knockout Human Erythroid Progenitor Cell Model

by Guoqiang Zhou, Haokun Zhang, Anning Lin, Zhen Wu, Ting Li, Xumin Zhang, Hongyan Chen, Daru Lu
Published 2022-03-01

Locked nucleic acid pentamers as universal PCR primers for genomic DNA amplification.

by Zhen Sun, Zhi Chen, Xiaoli Hou, Shuping Li, Haihong Zhu, Ji Qian, Daru Lu, Wei Liu
Published 2008-01-01

Targeted next-generation sequencing and long-read HiFi sequencing provide novel insights into clinically significant KLF1 variants

by Luyi Ye, Chen Wang, Aijing Li, Minghao Li, Yan Pi, Jingmin Yang, Ziyan Zhu, Daru Lu
Published 2024-03-01

Fine mapping of a region of chromosome 11q23.3 reveals independent locus associated with risk of glioma.

by Hongyan Chen, Bing Sun, Yingjie Zhao, Xiao Song, Weiwei Fan, Keke Zhou, Liangfu Zhou, Ying Mao, Daru Lu
Published 2012-01-01

Improved gene therapy for MFRP deficiency-mediated retinal degeneration by knocking down endogenous bicistronic Mfrp and Ctrp5 transcript

by Xiao Tian, Qingyun Zheng, Jinyan Xie, Qinlinglan Zhou, Letong Liang, Guotong Xu, Hongyan Chen, Chen Ling, Daru Lu
Published 2023-06-01

The establishment and application of preimplantation genetic haplotyping in embryo diagnosis for reciprocal and Robertsonian translocation carriers

by Shuo Zhang, Caixia Lei, Junping Wu, Jing Zhou, Haiyan Sun, Jing Fu, Yijuan Sun, Xiaoxi Sun, Daru Lu, Yueping Zhang
Published 2017-10-01

Silencing myelin protein zero-like 1 expression suppresses cell proliferation and invasiveness of human glioma cells by inhibiting multiple cancer-associated signal pathways

by Simiao Zhang, Sandian Zhang, Hongzhen Wang, Xuege Huang, Jinzhi Wang, Jingna Li, Dan Cheng, Hongwei Wang, Daru Lu, Yunliang Wang
Published 2021-12-01

A comprehensive and universal approach for embryo testing in patients with different genetic disorders

by Shuo Zhang, Caixia Lei, Junping Wu, Min Xiao, Jing Zhou, Saijuan Zhu, Jing Fu, Daru Lu, Xiaoxi Sun, Congjian Xu
Published 2021-07-01

Identification of a Novel Frameshift Variant of <i>ARR3</i> Related to X-Linked Female-Limited Early-Onset High Myopia and Study on the Effect of X Chromosome Inactivation on the M...

by Xuan Xiao, Jingmin Yang, Ying Li, Hongxia Yang, Yijian Zhu, Lianbing Li, Qinlinglan Zhou, Daru Lu, Ting Chen, Yafei Tian
Published 2023-01-01

Genome-wide association study in Chinese cohort identifies one novel hypospadias risk associated locus at 12q13.13

by Zhongzhong Chen, Xiaoling Lin, Yunping Lei, Haitao Chen, Richard H. Finnell, Yaping Wang, Jianfeng Xu, Daru Lu, Hua Xie, Fang Chen
Published 2019-12-01

Whole-exome sequencing identifies a novel mutation in spermine synthase gene (SMS) associated with Snyder-Robinson Syndrome

by Talal J. Qazi, Qiao Wu, Ailikemu Aierken, Daru Lu, Ihtisham Bukhari, Hafiz M. J. Hussain, Jingmin Yang, Asif Mir, Hong Qing
Published 2020-08-01