FRI-1 Is an Anti-Cancer Isoquinolinequinone That Inhibits the Mitochondrial Bioenergetics and Blocks Metabolic Shifts by Redox Disruption in Breast Cancer Cells

by Miguel Córdova-Delgado, Sebastián Fuentes-Retamal, Charlotte Palominos, Camila López-Torres, Daniela Guzmán-Rivera, Oney Ramírez-Rodríguez, Ramiro Araya-Maturana, Félix A. Urra
Published 2021-10-01

Complex Mitochondrial Dysfunction Induced by TPP⁺-Gentisic Acid and Mitochondrial Translation Inhibition by Doxycycline Evokes Synergistic Lethality in Breast Cancer Cel...

by Sebastián Fuentes-Retamal, Cristian Sandoval-Acuña, Liliana Peredo-Silva, Daniela Guzmán-Rivera, Mario Pavani, Natalia Torrealba, Jaroslav Truksa, Vicente Castro-Castillo, Mabel Catalán, Ulrike Kemmerling, Félix A. Urra, Jorge Ferreira
Published 2020-02-01

Aspirin-triggered resolvin D1 reduces parasitic cardiac load by decreasing inflammation in a murine model of early chronic Chagas disease.

by Ileana Carrillo, Rayane Aparecida Nonato Rabelo, César Barbosa, Mariana Rates, Sebastián Fuentes-Retamal, Fabiola González-Herrera, Daniela Guzmán-Rivera, Helena Quintero, Ulrike Kemmerling, Christian Castillo, Fabiana S Machado, Guillermo Díaz-Araya, Juan D Maya
Published 2021-11-01

Statins change the cytokine profile in Trypanosoma cruzi-infected U937 macrophages and murine cardiac tissue through Rho-associated kinases inhibition

by Fabiola González-Herrera, Natasha S. Clayton, Daniela Guzmán-Rivera, Ileana Carrillo, Christian Castillo, Mabel Catalán, Renatto Anfossi, Helena Quintero-Pertuz, María Elena Quilaqueo, Claudio Olea-Azar, Mario Rivera-Meza, Ulrike Kemmerling, Anne J. Ridley, Raúl Vivar, Juan Diego Maya
Published 2023-01-01