614 Co-stimulation via PD1–41BB chimeric switch receptor enhances function of TCR-T cells in an immune-suppressive milieu and under chronic antigen stimulation

by Elfriede Noessner, Daniel Sommermeyer, Christian Ellinger, Nadja Sailer, Melanie Salvermoser, Maria Gerget, Franziska Hasselmann, Monika Braun
Published 2020-11-01

161 Development of a CD8 co-receptor independent T cell receptor specific for tumor-associated antigen MAGE-A4 for next generation T cell-based immunotherapy

by Daniel Sommermeyer, Christian Ellinger, Giulia Longinotti, Dolores Schendel, Kathrin Davari, Tristan Holland, Laura Prassmayer, Kenneth Ganley, Lisa Pechilis, Iulia Diaconu, Prashant Nambiar, Mike Magee, Rer Nat
Published 2020-11-01

T-Cells Expressing a Highly Potent PRAME-Specific T-Cell Receptor in Combination with a Chimeric PD1-41BB Co-Stimulatory Receptor Show a Favorable Preclinical Safety Profile and St...

by Nadja Sailer, Ina Fetzer, Melanie Salvermoser, Monika Braun, Doris Brechtefeld, Christian Krendl, Christiane Geiger, Kathrin Mutze, Elfriede Noessner, Dolores J. Schendel, Maja Bürdek, Susanne Wilde, Daniel Sommermeyer
Published 2022-04-01

427 Development of iPSC-derived cytotoxic CD8+ T-cells as the basis for innovative off-the-shelf cancer immunotherapies

by Daniel Sommermeyer, Chloé Beuraud, Monika Braun, Michael Epstein, Philip Hublitz, Michael Esquerré, Audrey Holtzinger, Nadja Wagner, Riga Tawo, Florie Bertrand, Olivia Cypris, Pauline Barron, Stefanie Pfänder, Stephanie Sontag
Published 2023-11-01

Development of a CD8 co-receptor independent T-cell receptor specific for tumor-associated antigen MAGE-A4 for next generation T-cell-based immunotherapy

by Daniel Sommermeyer, Christian Ellinger, Giulia Longinotti, Dolores J Schendel, Michael S Magee, Kathrin Davari, Tristan Holland, Laura Prassmayer, Iulia Diaconu, Kenneth P Ganley, Lisa J Pechilis, Prashant R Nambiar
Published 2021-03-01

1515 Gene edited iPSC-derived macrophages (iMACs) show increased phagocytosis in pre-clinical tumor models

by Daniel Sommermeyer, Monika Braun, Michael Epstein, Tanja Schneider, Kathrin Haake, Michela Mirenda, Quentin Bernard, Philip Hublitz, Lucie Gouxette, Martin Briscadieu, Philine Scheinpflug, Garima Singh, Alica Hinkelmann, Michael Esquerré, Audrey Holtzinger, Michael Paillasse, Andreas Scheel, Markus Dangl, Nadja Wagner
Published 2023-11-01