Three-dimensional imaging of Prox1-EGFP transgenic mouse gonads reveals divergent modes of lymphangiogenesis in the testis and ovary.

by Terje Svingen, Mathias François, Dagmar Wilhelm, Peter Koopman
Published 2012-01-01

Mice Lacking Hbp1 Function Are Viable and Fertile.

by Cassy M Spiller, Dagmar Wilhelm, David A Jans, Josephine Bowles, Peter Koopman
Published 2017-01-01

Loss of NEDD4 causes complete XY gonadal sex reversal in mice

by Simon P. Windley, Chloé Mayère, Alice E. McGovern, Natasha L. Harvey, Serge Nef, Quenten Schwarz, Sharad Kumar, Dagmar Wilhelm
Published 2022-01-01

Signaling through the TGF beta-activin receptors ALK4/5/7 regulates testis formation and male germ cell development.

by Denise C Miles, Stephanie I Wakeling, Jessica M Stringer, Jocelyn A van den Bergen, Dagmar Wilhelm, Andrew H Sinclair, Patrick S Western
Published 2013-01-01

A new model of development of the mammalian ovary and follicles.

by Katja Hummitzsch, Helen F Irving-Rodgers, Nicholas Hatzirodos, Wendy Bonner, Laetitia Sabatier, Dieter P Reinhardt, Yoshikazu Sado, Yoshifumi Ninomiya, Dagmar Wilhelm, Raymond J Rodgers
Published 2013-01-01

Sox5 is involved in germ-cell regulation and sex determination in medaka following co-option of nested transposable elements

by Manfred Schartl, Susanne Schories, Yuko Wakamatsu, Yusuke Nagao, Hisashi Hashimoto, Chloé Bertin, Brigitte Mourot, Cornelia Schmidt, Dagmar Wilhelm, Lazaro Centanin, Yann Guiguen, Amaury Herpin
Published 2018-01-01

Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice.

by Jean-Luc Pitetti, Pierre Calvel, Yannick Romero, Béatrice Conne, Vy Truong, Marilena D Papaioannou, Olivier Schaad, Mylène Docquier, Pedro Luis Herrera, Dagmar Wilhelm, Serge Nef
Published 2013-01-01

Identification of novel markers of mouse fetal ovary development.

by Huijun Chen, James S Palmer, Rathi D Thiagarajan, Marcel E Dinger, Emmanuelle Lesieur, Hansheng Chiu, Alexandra Schulz, Cassy Spiller, Sean M Grimmond, Melissa H Little, Peter Koopman, Dagmar Wilhelm
Published 2012-01-01

Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.

by Debora Bogani, Pam Siggers, Rachel Brixey, Nick Warr, Sarah Beddow, Jessica Edwards, Debbie Williams, Dagmar Wilhelm, Peter Koopman, Richard A Flavell, Hongbo Chi, Harry Ostrer, Sara Wells, Michael Cheeseman, Andy Greenfield
Published 2009-09-01

Dynamic expression patterns of Irx3 and Irx5 during germline nest breakdown and primordial follicle formation promote follicle survival in mouse ovaries.

by Anqi Fu, Sydney M Oberholtzer, Stefan Bagheri-Fam, Raphael H Rastetter, Claire Holdreith, Valeria L Caceres, Steven V John, Sarah A Shaw, Kathleen J Krentz, Xiaoyun Zhang, Chi-Chung Hui, Dagmar Wilhelm, Joan S Jorgensen
Published 2018-08-01

A Human Homozygous <i>HELQ</i> Missense Variant Does Not Cause Premature Ovarian Insufficiency in a Mouse Model

by Shabnam Bakhshalizadeh, Anthony D. Bird, Rajini Sreenivasan, Katrina M. Bell, Gorjana Robevska, Jocelyn van den Bergen, Mohammad Asghari-Jafarabadi, Andrew J. Kueh, Philippe Touraine, Anna Lokchine, Sylvie Jaillard, Katie L. Ayers, Dagmar Wilhelm, Andrew H. Sinclair, Elena J. Tucker
Published 2024-03-01

TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway

by Moïra Rossitto, Stephanie Déjardin, Chris M. Rands, Stephanie Le Gras, Roberta Migale, Mahmoud-Reza Rafiee, Yasmine Neirijnck, Alain Pruvost, Anvi Laetitia Nguyen, Guillaume Bossis, Florence Cammas, Lionel Le Gallic, Dagmar Wilhelm, Robin Lovell-Badge, Brigitte Boizet-Bonhoure, Serge Nef, Francis Poulat
Published 2022-07-01

A novel evolutionary conserved mechanism of RNA stability regulates synexpression of primordial germ cell-specific genes prior to the sex-determination stage in medaka.

by Amaury Herpin, Cornelia Schmidt, Susanne Kneitz, Clara Gobé, Martina Regensburger, Aurélie Le Cam, Jérome Montfort, Mateus C Adolfi, Christina Lillesaar, Dagmar Wilhelm, Michael Kraeussling, Brigitte Mourot, Béatrice Porcon, Maëlle Pannetier, Eric Pailhoux, Laurence Ettwiller, Dirk Dolle, Yann Guiguen, Manfred Schartl
Published 2019-04-01

The gene encoding the ketogenic enzyme HMGCS2 displays a unique expression during gonad development in mice.

by Stefan Bagheri-Fam, Huijun Chen, Sean Wilson, Katie Ayers, James Hughes, Frederique Sloan-Bena, Pierre Calvel, Gorjana Robevska, Beatriz Puisac, Kamila Kusz-Zamelczyk, Stefania Gimelli, Anna Spik, Jadwiga Jaruzelska, Alina Warenik-Szymankiewicz, Sultana Faradz, Serge Nef, Juan Pié, Paul Thomas, Andrew Sinclair, Dagmar Wilhelm
Published 2020-01-01

Loss of function mutation in the palmitoyl-transferase HHAT leads to syndromic 46,XY disorder of sex development by impeding Hedgehog protein palmitoylation and signaling.

by Patrick Callier, Pierre Calvel, Armine Matevossian, Periklis Makrythanasis, Pascal Bernard, Hiroshi Kurosaka, Anne Vannier, Christel Thauvin-Robinet, Christelle Borel, Séverine Mazaud-Guittot, Antoine Rolland, Christèle Desdoits-Lethimonier, Michel Guipponi, Céline Zimmermann, Isabelle Stévant, Françoise Kuhne, Béatrice Conne, Federico Santoni, Sandy Lambert, Frederic Huet, Francine Mugneret, Jadwiga Jaruzelska, Laurence Faivre, Dagmar Wilhelm, Bernard Jégou, Paul A Trainor, Marilyn D Resh, Stylianos E Antonarakis, Serge Nef
Published 2014-05-01