Inactivation of PLK4-STIL Module Prevents Self-Renewal and Triggers p53-Dependent Differentiation in Human Pluripotent Stem Cells

by Tereza Renzova, Dasa Bohaciakova, Milan Esner, Veronika Pospisilova, Tomas Barta, Ales Hampl, Lukas Cajanek
Published 2018-10-01

Generation of the Human iPSC Line from Spontaneous Late-Onset Alzheimer’s Disease Patient with ApoE3/3 Genotype and Sex-, Age-, and ApoE-Matched Healthy Control

by Sona Kadakova, Jan Raska, Hana Hribkova, Veronika Fedorova, Jiri Sedmik, Klara Plesingrova, Katerina Sheardova, Dasa Bohaciakova
Published 2024-02-01

Generation of three human iPSC lines from patients with a spontaneous late-onset Alzheimer’s disease and three sex- and age-matched healthy controls

by Jan Raska, Hana Klimova, Katerina Sheardova, Veronika Fedorova, Hana Hribkova, Veronika Pospisilova, Simona Vochyanova, Tereza Vanova, Dasa Bohaciakova
Published 2021-05-01

Generation of six human iPSC lines from patients with a familial Alzheimer’s disease (n = 3) and sex- and age-matched healthy controls (n = 3)

by Jan Raska, Hana Hribkova, Hana Klimova, Veronika Fedorova, Martin Barak, Tomas Barta, Veronika Pospisilova, Simona Vochyanova, Tereza Vanova, Dasa Bohaciakova
Published 2021-05-01

The Effects of Bilirubin and Lumirubin on the Differentiation of Human Pluripotent Cell-Derived Neural Stem Cells

by Nikola Capková, Veronika Pospíšilová, Veronika Fedorová, Jan Raška, Kateřina Pospíšilová, Matteo Dal Ben, Aleš Dvořák, Jitka Viktorová, Dáša Bohačiaková, Libor Vítek
Published 2021-09-01

Hypoxia/Hif1α prevents premature neuronal differentiation of neural stem cells through the activation of Hes1

by Josef Večeřa, Jiřina Procházková, Veronika Šumberová, Veronika Pánská, Hana Paculová, Martina Kohutková Lánová, Jan Mašek, Dáša Bohačiaková, Emma Rachel Andersson, Jiří Pacherník
Published 2020-05-01

Glioblastoma and cerebral organoids: development and analysis of an in vitro model for glioblastoma migration

by Veronika Fedorova, Veronika Pospisilova, Tereza Vanova, Katerina Amruz Cerna, Pavel Abaffy, Jiri Sedmik, Jan Raska, Simona Vochyanova, Zuzana Matusova, Jana Houserova, Lukas Valihrach, Zdenek Hodny, Dasa Bohaciakova
Published 2023-04-01

Targeted mass spectrometry for monitoring of neural differentiation

by Rita Sucha, Martina Kubickova, Jakub Cervenka, Marian Hruska-Plochan, Dasa Bohaciakova, Katerina Vodickova Kepkova, Tereza Novakova, Katerina Budkova, Andrej Susor, Martin Marsala, Jan Motlik, Hana Kovarova, Petr Vodicka
Published 2021-08-01

Differentiation of neural rosettes from human pluripotent stem cells in vitro is sequentially regulated on a molecular level and accomplished by the mechanism reminiscent of second...

by Veronika Fedorova, Tereza Vanova, Lina Elrefae, Jakub Pospisil, Martina Petrasova, Veronika Kolajova, Zuzana Hudacova, Jana Baniariova, Martin Barak, Lucie Peskova, Tomas Barta, Marketa Kaucka, Michael Killinger, Josef Vecera, Ondrej Bernatik, Lukas Cajanek, Hana Hribkova, Dasa Bohaciakova
Published 2019-10-01

Cerebral organoids derived from patients with Alzheimer’s disease with PSEN1/2 mutations have defective tissue patterning and altered development

by Tereza Vanova, Jiri Sedmik, Jan Raska, Katerina Amruz Cerna, Petr Taus, Veronika Pospisilova, Marketa Nezvedova, Veronika Fedorova, Sona Kadakova, Hana Klimova, Michaela Capandova, Petra Orviska, Petr Fojtik, Simona Bartova, Karla Plevova, Zdenek Spacil, Hana Hribkova, Dasa Bohaciakova
Published 2023-11-01

A scalable solution for isolating human multipotent clinical-grade neural stem cells from ES precursors

by Dasa Bohaciakova, Marian Hruska-Plochan, Rachel Tsunemoto, Wesley D. Gifford, Shawn P. Driscoll, Thomas D. Glenn, Stephanie Wu, Silvia Marsala, Michael Navarro, Takahiro Tadokoro, Stefan Juhas, Jana Juhasova, Oleksandr Platoshyn, David Piper, Vickie Sheckler, Dara Ditsworth, Samuel L. Pfaff, Martin Marsala
Published 2019-03-01

Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s Disease drug candidate

by Michal Nemergut, Sérgio M. Marques, Lukas Uhrik, Tereza Vanova, Marketa Nezvedova, Darshak Chandulal Gadara, Durga Jha, Jan Tulis, Veronika Novakova, Joan Planas-Iglesias, Antonin Kunka, Anthony Legrand, Hana Hribkova, Veronika Pospisilova, Jiri Sedmik, Jan Raska, Zbynek Prokop, Jiri Damborsky, Dasa Bohaciakova, Zdenek Spacil, Lenka Hernychova, David Bednar, Martin Marek
Published 2023-06-01