Wnt/β-catenin Signaling in Tissue Self-Organization

by Kelvin W. Pond, Konstantin Doubrovinski, Curtis A. Thorne
Published 2020-08-01

Pyrvinium, a potent small molecule Wnt inhibitor, promotes wound repair and post-MI cardiac remodeling.

by Sarika Saraswati, Maria P Alfaro, Curtis A Thorne, James Atkinson, Ethan Lee, Pampee P Young
Published 2010-11-01

Selective Small Molecule Targeting β-Catenin Function Discovered by In Vivo Chemical Genetic Screen

by Jijun Hao, Ada Ao, Li Zhou, Clare K. Murphy, Audrey Y. Frist, Jessica J. Keel, Curtis A. Thorne, Kwangho Kim, Ethan Lee, Charles C. Hong
Published 2013-09-01

Live-cell imaging in human colonic monolayers reveals ERK waves limit the stem cell compartment to maintain epithelial homeostasis

by Kelvin W Pond, Julia M Morris, Olga Alkhimenok, Reeba P Varghese, Carly R Cabel, Nathan A Ellis, Jayati Chakrabarti, Yana Zavros, Juanita L Merchant, Curtis A Thorne, Andrew L Paek
Published 2022-09-01

High-fat diet plus HNF1A variant promotes polyps by activating β-catenin in early-onset colorectal cancer

by Heyu Song, Ricky A. Sontz, Matthew J. Vance, Julia M. Morris, Sulaiman Sheriff, Songli Zhu, Suzann Duan, Jiping Zeng, Erika Koeppe, Ritu Pandey, Curtis A. Thorne, Elena M. Stoffel, Juanita L. Merchant
Published 2023-07-01

Development of Human Pituitary Neuroendocrine Tumor Organoids to Facilitate Effective Targeted Treatments of Cushing’s Disease

by Jayati Chakrabarti, Ritu Pandey, Jared M. Churko, Jennifer Eschbacher, Saptarshi Mallick, Yuliang Chen, Beth Hermes, Palash Mallick, Ben N. Stansfield, Kelvin W. Pond, Curtis A. Thorne, Kevin C. J. Yuen, Andrew S. Little, Yana Zavros
Published 2022-10-01

Convergent antibody responses to the SARS-CoV-2 spike protein in convalescent and vaccinated individuals

by Elaine C. Chen, Pavlo Gilchuk, Seth J. Zost, Naveenchandra Suryadevara, Emma S. Winkler, Carly R. Cabel, Elad Binshtein, Rita E. Chen, Rachel E. Sutton, Jessica Rodriguez, Samuel Day, Luke Myers, Andrew Trivette, Jazmean K. Williams, Edgar Davidson, Shuaizhi Li, Benjamin J. Doranz, Samuel K. Campos, Robert H. Carnahan, Curtis A. Thorne, Michael S. Diamond, James E. Crowe, Jr.
Published 2021-08-01