Targeted delivery to inflammatory monocytes for efficient RNAi-mediated immuno-intervention in auto-immune arthritis

by Présumey Jessy, Courties Gabriel, Charbonnier Louis-Marie, Escriou Virginie, Scherman Daniel, Pers Yves-Marie, Louis-Plence Pascale, Kyburz Diego, Gay Steffen, Jorgensen Christian, Apparailly Florence
Published 2011-11-01

NAMPT/Visfatin expression by inflammatory monocytes mediates arthritis pathogenesis by promoting IL-17–producing T cells

by Présumey Jessy, Courties Gabriel, Louis-Plence Pascale, Escriou Virginie, Scherman Daniel, Pers Yves-Marie, Yssel Hans, Pène Jérôme, Kyburz Diego, Gay Steffen, Jorgensen Christian, Apparailly Florence
Published 2012-11-01

In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing

by Courties, Gabriel, Heidt, Timo, Sebas, Matthew, Iwamoto, Yoshiko, Jeon, Derrick, Truelove, Jessica, Tricot, Benoit, Wojtkiewicz, Greg, Dutta, Partha, Sager, Hendrik B., Borodovsky, Anna, Novobrantseva, Tatiana, Klebanov, Boris, Fitzgerald, Kevin, Anderson, Daniel G., Libby, Peter, Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias
Published 2019

Ischemic Stroke Activates Hematopoietic Bone Marrow Stem Cells

by Courties, Gabriel, Herisson, Fanny, Sager, Hendrik, Heidt, Timo, Ye, Yuxiang, Wei, Ying, Sun, Yuan, Severe, Nicolas, Dutta, Partha, Scharff, Jennifer, Scadden, David, Weissleder, Ralph, Swirski, Filip, Moskowitz, Michael, Nahrendorf, Matthias
Published 2019

In Vivo Silencing of the Transcription Factor IRF5 Reprograms the Macrophage Phenotype and Improves Infarct Healing

by Courties, Gabriel, Heidt, Timo, Sebas, Matthew, Iwamoto, Yoshiko, Jeon, Derrick, Truelove, Jessica, Tricot, Benoit, Wojtkiewicz, Greg, Dutta, Partha, Sager, Hendrik B., Borodovsky, Anna, Novobrantseva, Tatiana I., Klebanov, Boris, Fitzgerald, Kevin, Libby, Peter, Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias, Anderson, Daniel Griffith
Published 2016

Macrophages retain hematopoietic stem cells in the spleen via VCAM-1

by Dutta, Partha, Hoyer, Friedrich Felix, Grigoryeva, Lubov S., Sager, Hendrik B., Leuschner, Florian, Courties, Gabriel, Borodovsky, Anna, Novobrantseva, Tatiana, Ruda, Vera M., Fitzgerald, Kevin, Iwamoto, Yoshiko, Wojtkiewicz, Gregory, Sun, Yuan, Da Silva, Nicolas, Libby, Peter, Anderson, Daniel G., Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias
Published 2015

RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction

by Sager, Hendrik, Dutta, Partha, Dahlman, James, Hulsmans, Maarten, Courties, Gabriel, Sun, Yuan, Heidt, Timo, Vinegoni, Claudio, Borodovsky, Anna, Fitzgerald, Kevin, Wojtkiewicz, Gregory, Iwamoto, Yoshiko, Tricot, Benoit, Khan, Omar, Kauffman, Kevin, Xing, Yiping, Shaw, Taylor, Libby, Peter, Langer, Robert, Weissleder, Ralph, Swirski, Filip, Anderson, Daniel, Nahrendorf, Matthias
Published 2019

Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction

by Sager, Hendrik B., Heidt, Timo, Hulsmans, Maarten, Dutta, Partha, Courties, Gabriel P, Sebas, Matthew, Wojtkiewicz, Gregory R., Tricot, Benoit, Iwamoto, Yoshiko, Sun, Yuan, Weissleder, Ralph, Libby, Peter, Swirski, Filip K., Nahrendorf, Matthias
Published 2015

Myocardial Infarction Accelerates Atherosclerosis

by Leuschner, Florian, Robbins, Clinton, Iwamoto, Yoshiko, Thompson, Brian, Carlson, Alicia L., Heidt, Timo, Lasitschka, Felix, Etzrodt, Martin, Waterman, Peter, Waring, Michael T., Chicoine, Adam T., van der Laan, Anja M., Niessen, Hans W.M., Piek, Jan J., Rubin, Barry B., Butany, Jagdish, Katus, Hugo A., Murphy, Sabina A., Pittet, Mikael J., Lin, Charles P., Dutta, Partha, Courties, Gabriel P, Wei, Ying, Gorbatov, Rostic, Majmudar, Maulik D, Stone, James Robert, Morrow, David Andrew, Sabatine, Marc Steven, Vinegoni, Claudio, Moskowitz, Michael Arthur, Libby, Peter, Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias
Published 2013

Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche

by Krohn-Grimberghe, Marvin, Mitchell, Michael J, Schloss, Maximilian J, Khan, Omar F, Courties, Gabriel, Guimaraes, Pedro PG, Rohde, David, Cremer, Sebastian, Kowalski, Piotr S, Sun, Yuan, Tan, Mingchee, Webster, Jamie, Wang, Karin, Iwamoto, Yoshiko, Schmidt, Stephen P, Wojtkiewicz, Gregory R, Nayar, Ribhu, Frodermann, Vanessa, Hulsmans, Maarten, Chung, Amanda, Hoyer, Friedrich Felix, Swirski, Filip K, Langer, Robert, Anderson, Daniel G, Nahrendorf, Matthias
Published 2021

Myocardial Infarction Activates CCR2+ Hematopoietic Stem and Progenitor Cells

by Dutta, Partha, Sager, Hendrik B, Stengel, Kristy R., Naxerova, Kamila, Courties, Gabriel P, Saez, Borja, Silberstein, Lev, Heidt, Timo, Sebas, Matthew, Sun, Yuan, Wojtkiewicz, Gregory, Feruglio, Paolo Fumene, King, Kevin Robert, Baker, Joshua N., van der Laan, Anja M., Borodovsky, Anna, Fitzgerald, Kevin, Hulsmans, Maarten, Hoyer, Friedrich Felix, Iwamoto, Yoshiko, Vinegoni, Claudio, Brown, Dennis, Di Carli, Marcelo, Libby, Peter, Hiebert, Scott W., Scadden, David Thomas, Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias
Published 2015

Chronic variable stress activates hematopoietic stem cells

by Heidt, Timo, Sager, Hendrik B., Courties, Gabriel, Dutta, Partha, Iwamoto, Yoshiko, Zaltsman, Alex, von zur Muhlen, Constantin, Bode, Christoph, Fricchione, Gregory L., Denninger, John, Lin, Charles P., Vinegoni, Claudio, Libby, Peter, Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias
Published 2015

Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease

by Keliher, Edmund J., Ye, Yu-Xiang, Wojtkiewicz, Gregory R., Aguirre, Aaron D., Tricot, Benoit, Senders, Max L., Groenen, Hannah, Fay, Francois, Perez-Medina, Carlos, Calcagno, Claudia, Carlucci, Giuseppe, Reiner, Thomas, Sun, Yuan, Courties, Gabriel, Iwamoto, Yoshiko, Kim, Hye-Yeong, Wang, Cuihua, Chen, John W., Swirski, Filip K., Wey, Hsiao-Ying, Hooker, Jacob, Fayad, Zahi A., Mulder, Willem J. M., Weissleder, Ralph, Nahrendorf, Matthias
Published 2017

Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche

by Krohn-Grimberghe, Marvin, Mitchell, Michael J, Schloss, Maximilian J, Khan, Omar F, Courties, Gabriel, Guimaraes, Pedro PG, Rohde, David, Cremer, Sebastian, Kowalski, Piotr S, Sun, Yuan, Tan, Mingchee, Webster, Jamie, Wang, Karin, Iwamoto, Yoshiko, Schmidt, Stephen P, Wojtkiewicz, Gregory R, Nayar, Ribhu, Frodermann, Vanessa, Hulsmans, Maarten, Chung, Amanda, Hoyer, Friedrich Felix, Swirski, Filip K, Langer, Robert, Anderson, Daniel G, Nahrendorf, Matthias
Published 2022

Macrophages retain hematopoietic stem cells in the spleen via VCAM-1

by Dutta, Partha, Hoyer, Friedrich Felix, Grigoryeva, Lubov S., Sager, Hendrik B., Leuschner, Florian, Courties, Gabriel, Borodovsky, Anna, Novobrantseva, Tatiana I., Ruda, Vera M., Fitzgerald, Kevin, Iwamoto, Yoshiko, Wojtkiewicz, Gregory, Sun, Yuan, Da Silva, Nicolas, Libby, Peter, Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias, Anderson, Daniel Griffith
Published 2015

Silencing of CCR2 in myocarditis

by Leuschner, Florian, Courties, Gabriel, Dutta, Partha, Mortensen, Luke, Gorbatov, Rostic, Sena, Brena, Novobrantseva, Tatiana, Borodovsky, Anna, Fitzgerald, Kevin, Koteliansky, Victor, Iwamoto, Yoshiko, Bohlender, Marina, Meyer, Soeren, Lasitschka, Felix, Meder, Benjamin, Katus, Hugo, Lin, Charles, Libby, Peter, Swirski, Filip, Anderson, Daniel, Weissleder, Ralph, Nahrendorf, Matthias
Published 2019

Monocyte-directed RNAi targeting CCR2 improves infarct healing in atherosclerosis-prone mice

by Majmudar, Maulik D., Keliher, Edmund J., Heidt, Timo, Leuschner, Florian, Truelove, Jessica, Sena, Brena F., Gorbatov, Rostic, Iwamoto, Yoshiko, Dutta, Partha, Wojtkiewicz, Gregory, Courties, Gabriel, Sebas, Matt, Borodovsky, Anna, Fitzgerald, Kevin, Nolte, Marc W., Dickneite, Gerhard, Chen, John W., Anderson, Daniel G., Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias
Published 2019

Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis

by Ye, Yu-Xiang, Calcagno, Claudia, Binderup, Tina, Courties, Gabriel, Keliher, Edmund, Wojtkiewicz, Gregory, Iwamoto, Yoshiko, Tang, Jun, Pérez-Medina, Carlos, Mani, Venkatesh, Ishino, Seigo, Johnbeck, Camilla Bardram, Knigge, Ulrich, Fayad, Zahi, Libby, Peter, Weissleder, Ralph, Tawakol, Ahmed, Dubey, Shipra, Belanger, Anthony, Di Carli, Marcelo F., Swirski, Filip, Kjaer, Andreas, Mulder, Willem J. M., Nahrendorf, Matthias
Published 2019

Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure

by Sager, Hendrik B., Hulsmans, Maarten, Lavine, Kory J., Moreira, Marina B., Heidt, Timo, Courties, Gabriel P, Sun, Yuan, Iwamoto, Yoshiko, Tricot, Benoit, Khan, Omar F., Dahlman, James E., Borodovsky, Anna, Fitzgerald, Kevin, Anderson, Daniel Griffith, Weissleder, Ralph, Libby, Peter, Swirski, Filip K., Nahrendorf, Matthias
Published 2016

Multimodal imaging of bacterial-host interface in mice and piglets with Staphylococcus aureus endocarditis

by Panizzi, Peter, Krohn-Grimberghe, Marvin, Keliher, Edmund J., Ye, Yu-Xiang, Grune, Jana, Frodermann, Vanessa, Sun, Yuan, Muse, Charlotte G., Bushey, Kaitlyn, Iwamoto, Yoshiko, van Leent, Mandy M. T., Meerwaldt, Anu, Toner, Yohana C., Munitz, Jazz, Maier, Alexander, Soultanidis, Georgios, Calcagno, Claudia, Pérez-Medina, Carlos, Carlucci, Giuseppe, Riddell, Kay P., Barney, Sharron, Horne, Glenn, Anderson, Brian, Maddur-Appajaiah, Ashoka, Verhamme, Ingrid M., Bock, Paul E., Wojtkiewicz, Gregory R., Courties, Gabriel, Swirski, Filip, Church, William R., Walz, Paul H., Tillson, D. Michael, Mulder, Willem J. M., Nahrendorf, Matthias
Published 2022