Radiation and Immunotherapy in Upper Gastrointestinal Cancers: The Current State of Play

by Noel E. Donlon, Robert Power, Conall Hayes, Maria Davern, John V. Reynolds, Joanne Lysaght
Published 2021-01-01

776 A role for immune checkpoint blockade to enhance T cell-mediated responses in combination with chemotherapy in oesophageal adenocarcinoma

by John Reynolds, Maria Davern, Joanne Lysaght, Andrew Sheppard, Stephen Maher, Noel Donlon, Fiona Connell, Conall Hayes, Ross King, Anshul Bhardwaj
Published 2020-11-01

Chemotherapy regimens induce inhibitory immune checkpoint protein expression on stem-like and senescent-like oesophageal adenocarcinoma cells

by Maria Davern, Noel E. Donlon, Andrew Sheppard, Fiona O’ Connell, Conall Hayes, Anshul Bhardwaj, Emma Foley, Dermot O’ Toole, Niamh Lynam-Lennon, Narayanasamy Ravi, John V. Reynolds, Stephen G. Maher, Joanne Lysaght
Published 2021-06-01

The Prognostic Value of the Lymph Node in Oesophageal Adenocarcinoma; Incorporating Clinicopathological and Immunological Profiling

by Noel E. Donlon, Maria Davern, Andrew Sheppard, Robert Power, Fiona O’Connell, Aisling B. Heeran, Ross King, Conall Hayes, Anshul Bhardwaj, James J. Phelan, Margaret R. Dunne, Narayanasamy Ravi, Claire L. Donohoe, Jacintha O’Sullivan, John V. Reynolds, Joanne Lysaght
Published 2021-08-01

Cooperation between chemotherapy and immune checkpoint blockade to enhance anti-tumour T cell immunity in oesophageal adenocarcinoma

by Maria Davern, Noel E. Donlon, Fiona O’ Connell, Andrew D. Sheppard, Conall Hayes, Ross King, Hugo Temperley, Christine Butler, Anshul Bhardwaj, Jenny Moore, Dara Bracken-Clarke, Claire Donohoe, Narayanasamy Ravi, John V. Reynolds, Stephen G. Maher, Melissa J. Conroy, Joanne Lysaght
Published 2022-06-01

PD-1 and TIGIT blockade differentially affect tumour cell survival under hypoxia and glucose deprived conditions in oesophageal adenocarcinoma; implications for overcoming resistan...

by Maria Davern, Marie-Claire Fitzgerald, Croí E. Buckley, Aisling B. Heeran, Noel E. Donlon, Jason McGrath, Fiona O’ Connell, Malvika R. Deshpande, Conall Hayes, Jamie MacDonald, Andrew D. Sheppard, John V. Reynolds, Stephen G. Maher, Niamh Lynam-Lennon, Brona Murphy, Joanne Lysaght
Published 2022-05-01

The Impact of Esophageal Oncological Surgery on Perioperative Immune Function; Implications for Adjuvant Immune Checkpoint Inhibition

by Noel E. Donlon, Noel E. Donlon, Maria Davern, Maria Davern, Andrew D. Sheppard, Andrew D. Sheppard, Fiona O’Connell, Margaret R. Dunne, Conall Hayes, Eimear Mylod, Eimear Mylod, Sinead Ramjit, Hugo Temperley, Michael Mac Lean, Gillian Cotter, Anshul Bhardwaj, Christine Butler, Melissa J. Conroy, Melissa J. Conroy, Jacintha O’Sullivan, Narayanasamy Ravi, Claire L. Donohoe, John V. Reynolds, Joanne Lysaght, Joanne Lysaght
Published 2022-01-01