Triple Active Antiretroviral Regimen Including Enfuvirtide Via the Biojector is Effective and Safe

by Mona Loutfy, Colin Kovacs
Published 2007-01-01

Impact of collection method on assessment of semen HIV RNA viral load.

by Brendan J W Osborne, Prameet M Sheth, Colin Kovacs, Tony Mazzulli, Rupert Kaul
Published 2011-01-01

21 Patient-derived HIV reservoirs can be stably engrafted into NSG mice and reactivated by latency-reversing agents in vivo

by Adam Ward, Enock Charleus, Sara Karandish, Erika Benko, Colin Kovacs, Ali Ramezani, R. Brad Jones
Published 2017-07-01

Recognizing Cognitive and Psychiatric Changes in the Post-Highly Active Antiretroviral Therapy Era

by Adriana Carvalhal, Jean-Guy Baril, Frederic Crouzat, Joss De Wet, Patrice Junod, Colin Kovacs, Nancy Sheehan
Published 2012-01-01

HIV delays IFN-α production from human plasmacytoid dendritic cells and is associated with SYK phosphorylation.

by Calvin C Lo, Jordan A Schwartz, Dylan J Johnson, Monica Yu, Nasra Aidarus, Shariq Mujib, Erika Benko, Martin Hyrcza, Colin Kovacs, Mario A Ostrowski
Published 2012-01-01

Characterizing the Relationship Between Neutralization Sensitivity and env Gene Diversity During ART Suppression

by Andrew Wilson, Leyn Shakhtour, Adam Ward, Adam Ward, Yanqin Ren, Melina Recarey, Eva Stevenson, Maria Korom, Colin Kovacs, Erika Benko, R. Brad Jones, Rebecca M. Lynch
Published 2021-09-01

Lysis of endogenously infected CD4+ T cell blasts by rIL-2 activated autologous natural killer cells from HIV-infected viremic individuals.

by Manuela Fogli, Domenico Mavilio, Enrico Brunetta, Stefania Varchetta, Khaled Ata, Gregg Roby, Colin Kovacs, Dean Follmann, Daniela Pende, Jeffrey Ward, Edward Barker, Emanuela Marcenaro, Alessandro Moretta, Anthony S Fauci
Published 2008-07-01

HIV-specific T-cells accumulate in the liver in HCV/HIV co-infection.

by Bahareh Vali, Feng Yun Yue, R Brad Jones, Prameet M Sheth, Rupert Kaul, Michael R Betts, David Wong, Colin Kovacs, Mona Loutfy, Andrew Common, Roberta Halpenny, Mario A Ostrowski
Published 2008-01-01

Histone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytes.

by Richard Brad Jones, Rachel O'Connor, Stefanie Mueller, Maria Foley, Gregory L Szeto, Dan Karel, Mathias Lichterfeld, Colin Kovacs, Mario A Ostrowski, Alicja Trocha, Darrell J Irvine, Bruce D Walker
Published 2014-08-01

Tim-3 negatively regulates cytotoxicity in exhausted CD8+ T cells in HIV infection.

by Ali Sakhdari, Shariq Mujib, Bahareh Vali, Feng Yun Yue, Sonya MacParland, Kiera Clayton, Richard Bradley Jones, Jun Liu, Erika Yue Lee, Erika Benko, Colin Kovacs, Jennifer Gommerman, Rupert Kaul, Mario A Ostrowski
Published 2012-01-01

The semen microbiome and its relationship with local immunology and viral load in HIV infection.

by Cindy M Liu, Brendan J W Osborne, Bruce A Hungate, Kamnoosh Shahabi, Sanja Huibner, Richard Lester, Michael G Dwan, Colin Kovacs, Tania L Contente-Cuomo, Erika Benko, Maliha Aziz, Lance B Price, Rupert Kaul
Published 2014-07-01

HCV Specific IL-21 Producing T Cells but Not IL-17A Producing T Cells Are Associated with HCV Viral Control in HIV/HCV Coinfection.

by Sonya A MacParland, Saleh M Fadel, Vesna Mihajlovic, Ali Fawaz, Connie Kim, A K M Nur-Ur Rahman, Jun Liu, Rupert Kaul, Colin Kovacs, Jason Grebely, Gregory J Dore, David K Wong, Mario A Ostrowski
Published 2016-01-01

IL-10-producing B cells are induced early in HIV-1 infection and suppress HIV-1-specific T cell responses.

by Jun Liu, Wei Zhan, Connie J Kim, Kiera Clayton, Hanqi Zhao, Erika Lee, Jin Chao Cao, Blake Ziegler, Alexander Gregor, Feng Yun Yue, Sanja Huibner, Sonya MacParland, Jordan Schwartz, Hai Han Song, Erika Benko, Gabor Gyenes, Colin Kovacs, Rupert Kaul, Mario Ostrowski
Published 2014-01-01

Ex vivo Stimulatory Capacity of TLR3 and TLR4 is reduced in HIV-Infected Rapid Progressors and Enhanced Long-Term Non-Progressors

by Steven E. Bosinger,1,2 Prameet M. Sheth,3 Ali Danesh,2,4 Leonard Noay,5 Roberta Halpenny,5 Shari Gordon,6,7,8 Silvija Staprans,7,8 Guido Silvestri,6 Colin Kovacs,5 Rupert Kaul,3 and David J. Kelvin.2,4
Published 2007-08-01

T-cell responses targeting HIV Nef uniquely correlate with infected cell frequencies after long-term antiretroviral therapy.

by Allison S Thomas, Kimberley L Jones, Rajesh T Gandhi, Deborah K McMahon, Joshua C Cyktor, Dora Chan, Szu-Han Huang, Ronald Truong, Alberto Bosque, Amanda B Macedo, Colin Kovacs, Erika Benko, Joseph J Eron, Ronald J Bosch, Christina M Lalama, Samuel Simmens, Bruce D Walker, John W Mellors, R Brad Jones
Published 2017-09-01

The Canadian HIV and aging cohort study - determinants of increased risk of cardio-vascular diseases in HIV-infected individuals: rationale and study protocol

by Madeleine Durand, Carl Chartrand-Lefebvre, Jean-Guy Baril, Sylvie Trottier, Benoit Trottier, Marianne Harris, Sharon Walmsley, Brian Conway, Alexander Wong, Jean-Pierre Routy, Colin Kovacs, Paul A. MacPherson, Kenneth Marc Monteith, Samer Mansour, George Thanassoulis, Michal Abrahamowicz, Zhitong Zhu, Christos Tsoukas, Petronela Ancuta, Nicole Bernard, Cécile L. Tremblay, For the investigators of the Canadian HIV and Aging Cohort Study
Published 2017-09-01

Effective and targeted latency reversal in CD4+ T cells from individuals on long term combined antiretroviral therapy initiated during chronic HIV-1 infection

by Minh Ha Ngo, Joshua Pankrac, Ryan C. Y. Ho, Emmanuel Ndashimye, Rahul Pawa, Renata Ceccacci, Tsigereda Biru, Abayomi S. Olabode, Katja Klein, Yue Li, Colin Kovacs, Robert Assad, Jeffrey M. Jacobson, David H. Canaday, Stephen Tomusange, Samiri Jamiru, Aggrey Anok, Taddeo Kityamuweesi, Paul Buule, Ronald M. Galiwango, Steven J. Reynolds, Thomas C. Quinn, Andrew D. Redd, Jessica L. Prodger, Jamie F. S. Mann, Eric J. Arts
Published 2024-12-01

Correlates of Breakthrough SARS-CoV-2 Infections in People with HIV: Results from the CIHR CTN 328 Study

by Cecilia T. Costiniuk, Terry Lee, Joel Singer, Yannick Galipeau, Corey Arnold, Marc-André Langlois, Judy Needham, Mohammad-Ali Jenabian, Ann N. Burchell, Hasina Samji, Catharine Chambers, Sharon Walmsley, Mario Ostrowski, Colin Kovacs, Darrell H. S. Tan, Marianne Harris, Mark Hull, Zabrina L. Brumme, Hope R. Lapointe, Mark A. Brockman, Shari Margolese, Enrico Mandarino, Suzanne Samarani, Bertrand Lebouché, Jonathan B. Angel, Jean-Pierre Routy, Curtis L. Cooper, Aslam H. Anis
Published 2024-04-01

A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes.

by R Brad Jones, Stefanie Mueller, Rachel O'Connor, Katherine Rimpel, Derek D Sloan, Dan Karel, Hing C Wong, Emily K Jeng, Allison S Thomas, James B Whitney, So-Yon Lim, Colin Kovacs, Erika Benko, Sara Karandish, Szu-Han Huang, Maria J Buzon, Mathias Lichterfeld, Alivelu Irrinki, Jeffrey P Murry, Angela Tsai, Helen Yu, Romas Geleziunas, Alicja Trocha, Mario A Ostrowski, Darrell J Irvine, Bruce D Walker
Published 2016-04-01

HIV-1 diversity considerations in the application of the Intact Proviral DNA Assay (IPDA)

by Natalie N. Kinloch, Yanqin Ren, Winiffer D. Conce Alberto, Winnie Dong, Pragya Khadka, Szu Han Huang, Talia M. Mota, Andrew Wilson, Aniqa Shahid, Don Kirkby, Marianne Harris, Colin Kovacs, Erika Benko, Mario A. Ostrowski, Perla M. Del Rio Estrada, Avery Wimpelberg, Christopher Cannon, W. David Hardy, Lynsay MacLaren, Harris Goldstein, Chanson J. Brumme, Guinevere Q. Lee, Rebecca M. Lynch, Zabrina L. Brumme, R. Brad Jones
Published 2021-01-01