Multitargeted anti-infective drugs: resilience to resistance in the antimicrobial resistance era

by Colin J Suckling, Iain S Hunter, Fraser J Scott
Published 2022-03-01

2,2,2-Trifluoro-N-(isoquinolin-5-ylmethyl)acetamide

by Alan R. Kennedy, Abedawn I. Khalaf, Colin J. Suckling
Published 2010-01-01

Crystal structure of N,N-dimethyl-2-[(4-methylbenzyl)sulfonyl]ethanamine

by Alan R. Kennedy, Abedawn I. Khalaf, Fraser J. Scott, Colin J. Suckling
Published 2015-07-01

Four pyrrole derivatives used as building blocks in the synthesis of minor-groove binders

by Alan R. Kennedy, Abedawn I. Khalaf, Fraser J. Scott, Colin J. Suckling
Published 2017-02-01

Manganese dioxide mediated one-pot synthesis of methyl 9H-pyrido[3,4-b]indole-1-carboxylate: Concise synthesis of alangiobussinine

by Jessica Baiget, Sabin Llona-Minguez, Stuart Lang, Simon P. MacKay, Colin J. Suckling, Oliver B. Sutcliffe
Published 2011-10-01

Dendritic cells provide a therapeutic target for synthetic small molecule analogues of the parasitic worm product, ES-62

by Felicity E. Lumb, James Doonan, Kara S. Bell, Miguel A. Pineda, Marlene Corbet, Colin J. Suckling, Margaret M. Harnett, William Harnett
Published 2017-05-01

Protection Against Arthritis by the Parasitic Worm Product ES-62, and Its Drug-Like Small Molecule Analogues, Is Associated With Inhibition of Osteoclastogenesis

by James Doonan, Felicity E. Lumb, Miguel A. Pineda, Anuradha Tarafdar, Jenny Crowe, Aneesah M. Khan, Colin J. Suckling, Margaret M. Harnett, William Harnett
Published 2018-05-01

Suppression of inflammatory arthritis by the parasitic worm product ES-62 is associated with epigenetic changes in synovial fibroblasts

by Marlene Corbet, Miguel A. Pineda, Kun Yang, Anuradha Tarafdar, Sarah McGrath, Rinako Nakagawa, Felicity E. Lumb, Colin J. Suckling, William Harnett, Margaret M. Harnett
Published 2021-11-01

Suppression of inflammatory arthritis by the parasitic worm product ES-62 is associated with epigenetic changes in synovial fibroblasts.

by Marlene Corbet, Miguel A Pineda, Kun Yang, Anuradha Tarafdar, Sarah McGrath, Rinako Nakagawa, Felicity E Lumb, Colin J Suckling, William Harnett, Margaret M Harnett
Published 2021-11-01

Protection against lung pathology during obesity-accelerated ageing in mice by the parasitic worm product ES-62

by Margaret M. Harnett, Felicity E. Lumb, Jenny Crowe, James Doonan, Geraldine Buitrago, Stephanie Brown, Gillian Thom, Amy MacDonald, Colin J. Suckling, Colin Selman, William Harnett
Published 2023-11-01

The parasitic worm product ES-62 protects the osteoimmunology axis in a mouse model of obesity-accelerated ageing

by Margaret M. Harnett, James Doonan, Felicity E. Lumb, Jenny Crowe, Roel Olde Damink, Geraldine Buitrago, Josephine Duncombe-Moore, Debbie I. Wilkinson, Colin J. Suckling, Colin Selman, William Harnett
Published 2022-08-01

Selective Anti-Leishmanial Strathclyde Minor Groove Binders Using an N-Oxide Tail-Group Modification

by Marina C. Perieteanu, Leah M. C. McGee, Craig D. Shaw, Donna S. MacMillan, Abedawn I. Khalaf, Kirsten Gillingwater, Rebecca Beveridge, Katharine C. Carter, Colin J. Suckling, Fraser J. Scott
Published 2022-10-01

Failure of the Anti-Inflammatory Parasitic Worm Product ES-62 to Provide Protection in Mouse Models of Type I Diabetes, Multiple Sclerosis, and Inflammatory Bowel Disease

by James Doonan, David Thomas, Michelle H. Wong, Hazel J. Ramage, Lamyaa Al-Riyami, Felicity E. Lumb, Kara S. Bell, Karen J. Fairlie-Clarke, Colin J. Suckling, Kathrin S. Michelsen, Hui-Rong Jiang, Anne Cooke, Margaret M. Harnett, William Harnett
Published 2018-10-01