Exploring <i>Proteus mirabilis</i> Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation

by Samar S. Elbaramawi, Ahmed G. Eissa, Nada A. Noureldin, Claire Simons
Published 2023-09-01

Synthesis, computational study and biological evaluation of 9-acridinyl and 1-coumarinyl-1,2,3-triazole-4-yl derivatives as topoisomerase II inhibitors

by Gehan A. Abdel-Hafez, Abdel-Maaboud I. Mohamed, Adel F. Youssef, Claire Simons, Ahmed S. Aboraia
Published 2022-12-01

Design, computational studies, synthesis and in vitro antimicrobial evaluation of benzimidazole based thio-oxadiazole and thio-thiadiazole analogues

by Nada A. Noureldin, Jennifer Richards, Hend Kothayer, Mohammed M. Baraka, Sobhy M. Eladl, Mandy Wootton, Claire Simons
Published 2021-10-01

Surface hydrophobics mediate functional dimerization of CYP121A1 of Mycobacterium tuberculosis

by Amit Kumar, Christopher S. Campomizzi, Natalie Jay, Shaun Ferguson, Emelie-Jo Scheffler, James Lioi, Chengjian Tu, Jun Qu, Claire Simons, D. Fernando Estrada
Published 2021-01-01

Molecular Insights into Human Transmembrane Protease Serine-2 (TMPS2) Inhibitors against SARS-CoV2: Homology Modelling, Molecular Dynamics, and Docking Studies

by Safaa M. Kishk, Rania M. Kishk, Asmaa S. A. Yassen, Mohamed S. Nafie, Nader A. Nemr, Gamal ElMasry, Salim Al-Rejaie, Claire Simons
Published 2020-10-01

Long-term health outcomes of people with reduced kidney function in the UK: A modelling study using population health data.

by Iryna Schlackow, Claire Simons, Jason Oke, Benjamin Feakins, Christopher A O'Callaghan, F D Richard Hobbs, Daniel Lasserson, Richard J Stevens, Rafael Perera, Borislava Mihaylova
Published 2020-12-01

Adenine and benzimidazole-based mimics of REP-3123 as antibacterial agents against Clostridium difficile and Bacillus anthracis: Design, synthesis and biological evaluation

by Ahmed G. Eissa, James A. Blaxland, Rhodri O. Williams, Kamel A. Metwally, Sobhy M. El-Adl, El-Sayed M. Lashine, Leslie W.J. Baillie, Claire Simons
Published 2016-12-01

Statistical models for the deterioration of kidney function in a primary care population: A retrospective database analysis [version 2; peer review: 2 approved]

by Jason L Oke, Iryna Schlackow, Benjamin G Feakins, Claire Simons, Borislava Mihaylova, Daniel S Lasserson, Chris A O'Callaghan, Richard J Stevens, Rafael Perera, F D Richard Hobbs
Published 2022-08-01

Synthesis, Optimization, Antifungal Activity, Selectivity, and CYP51 Binding of New 2-Aryl-3-azolyl-1-indolyl-propan-2-ols

by Nicolas Lebouvier, Fabrice Pagniez, Young Min Na, Da Shi, Patricia Pinson, Mathieu Marchivie, Jean Guillon, Tarek Hakki, Rita Bernhardt, Sook Wah Yee, Claire Simons, Marie-Pierre Lézé, Rolf W. Hartmann, Angélique Mularoni, Guillaume Le Baut, Isabelle Krimm, Ruben Abagyan, Patrice Le Pape, Marc Le Borgne
Published 2020-08-01

Design and Synthesis of Imidazole and Triazole Pyrazoles as Mycobacterium Tuberculosis CYP121A1 Inhibitors

by Dr. Safaa M. Kishk, Dr. Kirsty J. McLean, Dr. Sakshi Sood, Darren Smith, Jack W.D. Evans, Prof. Mohamed A. Helal, Prof. Mohamed S. Gomaa, Prof. Ismail Salama, Prof. Samia M. Mostafa, Dr. Luiz Pedro S. de Carvalho, Colin W. Levy, Prof. Andrew W. Munro, Dr. Claire Simons
Published 2019-07-01

Association between systemic hemodynamics and septic acute kidney injury in critically ill patients: a retrospective observational study.

by Legrand, Matthieu, Dupuis, Claire, Simon, Christelle, Gayat, Etienne, Mateo, Joaquim, Lukaszewicz, Anne-Claire, Payen, Didier
Published 2013

Evidence Synthesis and targeting further research for adherence and stratification in health economic evaluations

by Simons, Claire Louise
Published 2019

Genome-Wide Association Study of Circulating Vitamin D Levels

by Ahn, Jiyoung, Yu, Kai, Stolzenberg-Solomon, Rachael, McCullough, Marjorie L., Gallicchio, Lisa, Jacobs, Eric J., Helzlsouer, Kathy, Jacobs, Kevin B., Li, Qizhai, Weinstein, Stephanie J., Purdue, Mark, Virtamo, Jarmo, Horst, Ronald, Chanock, Stephen, Hayes, Richard B., Kraft, Peter, Albanes, Demetrius, Simon, Kelly Claire, Ascherio, Alberto B., Wheeler, William, Hunter, David J.
Published 2012