Glioblastoma Stem-Like Cells, Metabolic Strategy to Kill a Challenging Target

by Delphine Garnier, Ophélie Renoult, Marie-Clotilde Alves-Guerra, Marie-Clotilde Alves-Guerra, François Paris, François Paris, Claire Pecqueur, Claire Pecqueur
Published 2019-03-01

Targeting Metabolism to Induce Cell Death in Cancer Cells and Cancer Stem Cells

by Claire Pecqueur, Lisa Oliver, Kristell Oizel, Lisenn Lalier, François M. Vallette
Published 2013-01-01

The antitumor activity of human Vγ9Vδ2 T cells is impaired by TGF-β through significant phenotype, transcriptomic and metabolic changes

by Chirine Rafia, Chirine Rafia, Clément Loizeau, Clément Loizeau, Ophélie Renoult, Ophélie Renoult, Christelle Harly, Christelle Harly, Claire Pecqueur, Claire Pecqueur, Noémie Joalland, Noémie Joalland, Emmanuel Scotet, Emmanuel Scotet
Published 2023-01-01

Analysis of uncoupling protein 2-deficient mice upon anaesthesia and sedation revealed a role for UCP2 in locomotion.

by Marie-Clotilde Alves-Guerra, Caroline Aheng, Claire Pecqueur, Sandrine Masscheleyn, Pierre Louis Tharaux, Anne Druilhe, Daniel Ricquier, Etienne Challet, Bruno Miroux
Published 2012-01-01

Teriflunomide Treatment of Multiple Sclerosis Selectively Modulates CD8 Memory T Cells

by Gaëlle Tilly, Marion Cadoux, Alexandra Garcia, Jérémy Morille, Sandrine Wiertlewski, Sandrine Wiertlewski, Claire Pecqueur, Sophie Brouard, David Laplaud, David Laplaud, Nicolas Degauque
Published 2021-10-01

Sphingolipid distribution at mitochondria-associated membranes (MAMs) upon induction of apoptosis[S]

by Vincent Mignard, Nolwenn Dubois, Didier Lanoé, Marie-Pierre Joalland, Lisa Oliver, Claire Pecqueur, Dominique Heymann, François Paris, François M. Vallette, Lisenn Lalier
Published 2020-07-01

The centrosomal protein 131 participates in the regulation of mitochondrial apoptosis

by Clotilde C. N. Renaud, Kilian Trillet, Jane Jardine, Laura Merlet, Ophélie Renoult, Mélanie Laurent—Blond, Zoé Catinaud, Claire Pecqueur, Julie Gavard, Nicolas Bidère
Published 2023-12-01

UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses

by Esther Aguilar, Pauline Esteves, Tiphaine Sancerni, Véronique Lenoir, Thomas Aparicio, Frédéric Bouillaud, Renaud Dentin, Carina Prip-Buus, Daniel Ricquier, Claire Pecqueur, Sandra Guilmeau, Marie-Clotilde Alves-Guerra
Published 2019-08-01

The transcription factor ChREBP Orchestrates liver carcinogenesis by coordinating the PI3K/AKT signaling and cancer metabolism

by Emmanuel Benichou, Bolaji Seffou, Selin Topçu, Ophélie Renoult, Véronique Lenoir, Julien Planchais, Caroline Bonner, Catherine Postic, Carina Prip-Buus, Claire Pecqueur, Sandra Guilmeau, Marie-Clotilde Alves-Guerra, Renaud Dentin
Published 2024-02-01

Glutamine uptake and utilization of human mesenchymal glioblastoma in orthotopic mouse model

by Kristell Oizel, Chendong Yang, Ophelie Renoult, Fabien Gautier, Quyen N. Do, Noemie Joalland, Xiaofei Gao, Bookyung Ko, François Vallette, Woo-Ping Ge, François Paris, Ralph J. DeBerardinis, Claire Pecqueur
Published 2020-08-01

Osteoarthritic chondrocytes undergo a glycolysis-related metabolic switch upon exposure to IL-1b or TNF

by Anais Defois, Nina Bon, Alexandre Charpentier, Melina Georget, Nicolas Gaigeard, Frederic Blanchard, Antoine Hamel, Denis Waast, Jean Armengaud, Ophelie Renoult, Claire Pecqueur, Yves Maugars, Marie-Astrid Boutet, Jerome Guicheux, Claire Vinatier
Published 2023-06-01

UCP2 silencing restrains leukemia cell proliferation through glutamine metabolic remodeling

by Tiphaine Sancerni, Ophélie Renoult, Angèle Luby, Cédric Caradeuc, Véronique Lenoir, Mikael Croyal, Céline Ransy, Esther Aguilar, Catherine Postic, Gildas Bertho, Renaud Dentin, Carina Prip-Buus, Claire Pecqueur, Marie-Clotilde Alves-Guerra
Published 2022-10-01

Unraveling hallmark suitability for staging pre- and post-implantation stem cell models

by Constance Onfray, Simon Chevolleau, Eva Moinard, Océane Girard, Kasturi Mahadik, Ryan Allsop, Grigorios Georgolopoulos, Régis Lavigne, Ophélie Renoult, Irene Aksoy, Elsa Lemaitre, Philippe Hulin, Jean-François Ouimette, Thomas Fréour, Claire Pecqueur, Charles Pineau, Vincent Pasque, Claire Rougeulle, Laurent David
Published 2024-05-01

Parallel derivation of isogenic human primed and naive induced pluripotent stem cells

by Stéphanie Kilens, Dimitri Meistermann, Diego Moreno, Caroline Chariau, Anne Gaignerie, Arnaud Reignier, Yohann Lelièvre, Miguel Casanova, Céline Vallot, Steven Nedellec, Léa Flippe, Julie Firmin, Juan Song, Eric Charpentier, Jenna Lammers, Audrey Donnart, Nadège Marec, Wallid Deb, Audrey Bihouée, Cédric Le Caignec, Claire Pecqueur, Richard Redon, Paul Barrière, Jérémie Bourdon, Vincent Pasque, Magali Soumillon, Tarjei S. Mikkelsen, Claire Rougeulle, Thomas Fréour, Laurent David, The Milieu Intérieur Consortium
Published 2018-01-01

IL-15 Harnesses Pro-inflammatory Function of TEMRA CD8 in Kidney-Transplant Recipients

by Gaëlle Tilly, Gaëlle Tilly, Tra-My Doan-Ngoc, Tra-My Doan-Ngoc, Michelle Yap, Michelle Yap, Aurélie Caristan, Aurélie Caristan, Lola Jacquemont, Lola Jacquemont, Richard Danger, Richard Danger, Marion Cadoux, Marion Cadoux, Sarah Bruneau, Sarah Bruneau, Magali Giral, Magali Giral, Pierrick Guerif, Bryan Nicol, Bryan Nicol, Alexandra Garcia, Alexandra Garcia, David-Axel Laplaud, David-Axel Laplaud, Sophie Brouard, Sophie Brouard, Claire Pecqueur Hellman, Nicolas Degauque, Nicolas Degauque
Published 2017-06-01