Hypercapnia-Driven Skeletal Muscle Dysfunction in an Animal Model of Pulmonary Emphysema Suggests a Complex Phenotype

by Joseph Balnis, Joseph Balnis, Chun Geun Lee, Jack A. Elias, Ariel Jaitovich, Ariel Jaitovich
Published 2020-10-01

Host chitinase 3-like-1 is a universal therapeutic target for SARS-CoV-2 viral variants in COVID-19

by Suchitra Kamle, Bing Ma, Chang Min Lee, Gail Schor, Yang Zhou, Chun Geun Lee, Jack A Elias
Published 2022-06-01

Cytokine ranking via mutual information algorithm correlates cytokine profiles with presenting disease severity in patients infected with SARS-CoV-2

by Kelsey E Huntington, Anna D Louie, Chun Geun Lee, Jack A Elias, Eric A Ross, Wafik S El-Deiry
Published 2021-01-01

CHI3L1 enhances melanoma lung metastasis via regulation of T cell co-stimulators and CTLA-4/B7 axis

by Bing Ma, Suchitra Kamle, Bedia Akosman, Hina Khan, Chang-Min Lee, Chun Geun Lee, Jack A. Elias, Jack A. Elias
Published 2022-12-01

Targeting Chitinase 1 and Chitinase 3-Like 1 as Novel Therapeutic Strategy of Pulmonary Fibrosis

by Suh-Young Lee, Suh-Young Lee, Chang-Min Lee, Bing Ma, Suchitra Kamle, Jack A. Elias, Yang Zhou, Chun Geun Lee
Published 2022-03-01

Immunomodulation of Host Chitinase 3-Like 1 During a Mammary Pathogenic Escherichia coli Infection

by Koen Breyne, Jonas Steenbrugge, Kristel Demeyere, Chun Geun Lee, Jack A. Elias, Wolfram Petzl, David G. E. Smith, Pierre Germon, Evelyne Meyer
Published 2018-05-01

Chitotriosidase Activity Is Counterproductive in a Mouse Model of Systemic Candidiasis

by Nicholas A. Schmitz, Ritesh P. Thakare, Chun-Shiang Chung, Chang-Min Lee, Jack A. Elias, Chun Geun Lee, Brian W. LeBlanc
Published 2021-03-01

Mesenchymal stem cells exert their anti-asthmatic effects through macrophage modulation in a murine chronic asthma model

by Ruth Lee Kim, Ji-Young Bang, Jeonghyeon Kim, Yosep Mo, Yujin Kim, Chun-Geun Lee, Jack A. Elias, Hye Young Kim, Hye-Ryun Kang
Published 2022-06-01

Phospholipid scramblase-1 regulates innate type 2 inflammation in mouse lungs via CRTH2-dependent mechanisms

by Ashley Hernandez-Gutierrez, Sonoor Majid, Adam Eberle, Ashley Choi, Parand Sorkhdini, Dongqin Yang, Alina Xiaoyu Yang, Carmelissa Norbrun, Chuan Hua He, Chang-min Lee, Chun Geun Lee, Jack A. Elias, Yang Zhou
Published 2023-08-01

Epithelial cell mitochondrial dysfunction and PINK1 are induced by transforming growth factor-beta1 in pulmonary fibrosis.

by Avignat S Patel, Jin Woo Song, Sarah G Chu, Kenji Mizumura, Juan C Osorio, Ying Shi, Souheil El-Chemaly, Chun Geun Lee, Ivan O Rosas, Jack A Elias, Augustine M K Choi, Danielle Morse
Published 2015-01-01

Correction: Corrigendum: IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses

by Chang-Min Lee, Chuan Hua He, Adel M. Nour, Yang Zhou, Bing Ma, Jin Wook Park, Kyung Hee Kim, Charles Dela Cruz, Lokesh Sharma, Mahmoud L. Nasr, Yorgo Modis, Chun Geun Lee, Jack A. Elias
Published 2016-11-01

IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses

by Chang-Min Lee, Chuan Hua He, Adel M. Nour, Yang Zhou, Bing Ma, Jin Wook Park, Kyung Hee Kim, Charles Dela Cruz, Lokesh Sharma, Mahmoud L. Nasr, Yorgo Modis, Chun Geun Lee, Jack A. Elias
Published 2016-09-01

Chitinase 3-like-1 is a therapeutic target that mediates the effects of aging in COVID-19

by Suchitra Kamle, Bing Ma, Chuan Hua He, Bedia Akosman, Yang Zhou, Chang-Min Lee, Wafik S. El-Deiry, Kelsey Huntington, Olin Liang, Jason T. Machan, Min-Jong Kang, Hyeon Jun Shin, Emiko Mizoguchi, Chun Geun Lee, Jack A. Elias
Published 2021-11-01

The deubiquitinase UCHL3 mediates p300-dependent chemokine signaling in alveolar type II cells to promote pulmonary fibrosis

by Soo Yeon Lee, Soo-Yeon Park, Seung-Hyun Lee, Hyunsik Kim, Jae-Hwan Kwon, Jung-Yoon Yoo, Kyunggon Kim, Moo Suk Park, Chun Geun Lee, Jack A. Elias, Myung Hyun Sohn, Hyo Sup Shim, Ho-Geun Yoon
Published 2023-08-01

Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis

by Do-Hyun Kim, Hong-Jai Park, Sangho Lim, Ja-Hyun Koo, Hong-Gyun Lee, Jin Ouk Choi, Ji Hoon Oh, Sang-Jun Ha, Min-Jong Kang, Chang-Min Lee, Chun Geun Lee, Jack A. Elias, Je-Min Choi
Published 2018-02-01

Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment

by Zhao Shan, Leike Li, Constance Lynn Atkins, Meng Wang, Yankai Wen, Jongmin Jeong, Nicolas F Moreno, Dechun Feng, Xun Gui, Ningyan Zhang, Chun Geun Lee, Jack A Elias, William M Lee, Bin Gao, Fong Wilson Lam, Zhiqiang An, Cynthia Ju
Published 2021-06-01

Club cell-specific role of programmed cell death 5 in pulmonary fibrosis

by Soo-Yeon Park, Jung Yeon Hong, Soo Yeon Lee, Seung-Hyun Lee, Mi Jeong Kim, Soo Yeon Kim, Kyung Won Kim, Hyo Sup Shim, Moo Suk Park, Chun Geun Lee, Jack A. Elias, Myung Hyun Sohn, Ho-Geun Yoon
Published 2021-05-01

Chitinase 3-like 1 Regulates Cellular and Tissue Responses via IL-13 Receptor α2

by Chuan Hua He, Chun Geun Lee, Charles S. Dela Cruz, Chang-Min Lee, Yang Zhou, Farida Ahangari, Bing Ma, Erica L. Herzog, Stephen A. Rosenberg, Yue Li, Adel M. Nour, Chirag R. Parikh, Insa Schmidt, Yorgo Modis, Lloyd Cantley, Jack A. Elias
Published 2015-03-01

Chitinase 3-like 1 Regulates Cellular and Tissue Responses via IL-13 Receptor α2

by Chuan Hua He, Chun Geun Lee, Charles S. Dela Cruz, Chang-Min Lee, Yang Zhou, Farida Ahangari, Bing Ma, Erica L. Herzog, Stephen A. Rosenberg, Yue Li, Adel M. Nour, Chirag R. Parikh, Insa Schmidt, Yorgo Modis, Lloyd Cantley, Jack A. Elias
Published 2013-11-01

Chitinase 3-like 1 Regulates Cellular and Tissue Responses via IL-13 Receptor α2

by Chuan Hua He, Chun Geun Lee, Charles S. Dela Cruz, Chang-Min Lee, Yang Zhou, Farida Ahangari, Bing Ma, Erica L. Herzog, Stephen A. Rosenberg, Yue Li, Adel M. Nour, Chirag R. Parikh, Insa Schmidt, Yorgo Modis, Lloyd Cantley, Jack A. Elias
Published 2013-08-01