Host-derived protease promotes aggregation of Staphylococcus aureus by cleaving the surface protein SasG

by Heidi A. Crosby, Klara Keim, Jakub M. Kwiecinski, Christophe J. Langouët-Astrié, Kaori Oshima, Wells B. LaRivière, Eric P. Schmidt, Alexander R. Horswill
Published 2024-04-01

Heparan sulfate-dependent RAGE oligomerization is indispensable for pathophysiological functions of RAGE

by Miaomiao Li, Chih Yean Ong, Christophe J Langouët-Astrié, Lisi Tan, Ashwni Verma, Yimu Yang, Xiaoxiao Zhang, Dhaval K Shah, Eric P Schmidt, Ding Xu
Published 2022-02-01

Sodium bicarbonate cotransporter NBCe2 gene variants increase sodium and bicarbonate transport in human renal proximal tubule cells.

by John J Gildea, Peng Xu, Brandon A Kemp, Julia M Carlson, Hanh T Tran, Dora Bigler Wang, Christophe J Langouët-Astrié, Helen E McGrath, Robert M Carey, Pedro A Jose, Robin A Felder
Published 2018-01-01

Aging-Associated Augmentation of Gut Microbiome Virulence Capability Drives Sepsis Severity

by James F. Colbert, Joshua M. Kirsch, Christopher L. Erzen, Christophe J. Langouët-Astrié, Grace E. Thompson, Sarah A. McMurtry, Jennifer M. Kofonow, Charles E. Robertson, Elizabeth J. Kovacs, Ryan C. Sullivan, Joseph A. Hippensteel, Namrata V. Sawant, Nicole J. De Nisco, Bruce D. McCollister, Robert S. Schwartz, Alexander R. Horswill, Daniel N. Frank, Breck A. Duerkop, Eric P. Schmidt
Published 2023-06-01

Alveolar epithelial glycocalyx degradation mediates surfactant dysfunction and contributes to acute respiratory distress syndrome

by Alicia N. Rizzo, Sarah M. Haeger, Kaori Oshima, Yimu Yang, Alison M. Wallbank, Ying Jin, Marie Lettau, Lynda A. McCaig, Nancy E. Wickersham, J. Brennan McNeil, Igor Zakharevich, Sarah A. McMurtry, Christophe J. Langouët-Astrié, Katrina W. Kopf, Dennis R. Voelker, Kirk C. Hansen, Ciara M. Shaver, V. Eric Kerchberger, Ryan A. Peterson, Wolfgang M. Kuebler, Matthias Ochs, Ruud A.W. Veldhuizen, Bradford J. Smith, Lorraine B. Ware, Julie A. Bastarache, Eric P. Schmidt
Published 2022-01-01