Benchmarking of ATAC Sequencing Data From BGI’s Low-Cost DNBSEQ-G400 Instrument for Identification of Open and Occupied Chromatin Regions

by Marina Naval-Sanchez, Nikita Deshpande, Minh Tran, Jingyu Zhang, Majid Alhomrani, Majid Alhomrani, Walaa Alsanie, Walaa Alsanie, Quan Nguyen, Christian M. Nefzger
Published 2022-07-01

Bone Marrow Regulatory T Cells Are a Unique Population, Supported by Niche-Specific Cytokines and Plasmacytoid Dendritic Cells, and Required for Chronic Graft-Versus-Host Disease C...

by Jemma Nicholls, Benjamin Cao, Benjamin Cao, Laetitia Le Texier, Laura Yan Xiong, Christopher R. Hunter, Genesis Llanes, Ethan G. Aguliar, Wayne A. Schroder, Simon Phipps, Jason P. Lynch, Huimin Cao, Huimin Cao, Shen Y. Heazlewood, Shen Y. Heazlewood, Brenda Williams, Brenda Williams, Andrew D. Clouston, Christian M. Nefzger, Christian M. Nefzger, Christian M. Nefzger, Jose M. Polo, Jose M. Polo, Jose M. Polo, Susan K. Nilsson, Susan K. Nilsson, Bruce R. Blazar, Kelli P. A. MacDonald
Published 2021-09-01

A Versatile Strategy for Isolating a Highly Enriched Population of Intestinal Stem Cells

by Christian M. Nefzger, Thierry Jardé, Fernando J. Rossello, Katja Horvay, Anja S. Knaupp, David R. Powell, Joseph Chen, Helen E. Abud, Jose M. Polo
Published 2016-03-01

Generation of four iPSC lines from peripheral blood mononuclear cells (PBMCs) of an attention deficit hyperactivity disorder (ADHD) individual and a healthy sibling in an Australia...

by Janette Tong, Kyung Min Lee, Xiaodong Liu, Christian M. Nefzger, Prasidhee Vijayakumar, Ziarih Hawi, Ken C. Pang, Clare L. Parish, Jose M. Polo, Mark A. Bellgrove
Published 2019-01-01

SRSF3 promotes pluripotency through Nanog mRNA export and coordination of the pluripotency gene expression program

by Madara Ratnadiwakara, Stuart K Archer, Craig I Dent, Igor Ruiz De Los Mozos, Traude H Beilharz, Anja S Knaupp, Christian M Nefzger, Jose M Polo, Minna-Liisa Anko
Published 2018-05-01

Identification of dynamic undifferentiated cell states within the male germline

by Hue M. La, Juho-Antti Mäkelä, Ai-Leen Chan, Fernando J. Rossello, Christian M. Nefzger, Julien M. D. Legrand, Mia De Seram, Jose M. Polo, Robin M. Hobbs
Published 2018-07-01

Breaking constraint of mammalian axial formulae

by Gabriel M. Hauswirth, Victoria C. Garside, Lisa S. F. Wong, Heidi Bildsoe, Jan Manent, Yi-Cheng Chang, Christian M. Nefzger, Jaber Firas, Joseph Chen, Fernando J. Rossello, Jose M. Polo, Edwina McGlinn
Published 2022-01-01

Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity.

by Jueqiong Wang, Carlos Farkas, Aissa Benyoucef, Catherine Carmichael, Katharina Haigh, Nick Wong, Danny Huylebroeck, Marc P Stemmler, Simone Brabletz, Thomas Brabletz, Christian M Nefzger, Steven Goossens, Geert Berx, Jose M Polo, Jody J Haigh
Published 2021-09-01

Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1–3 in mesendoderm cell differentiation

by Enakshi Sinniah, Zhixuan Wu, Sophie Shen, Marina Naval-Sanchez, Xiaoli Chen, Junxian Lim, Abbigail Helfer, Abishek Iyer, Jiahui Tng, Andrew J. Lucke, Robert C. Reid, Meredith A. Redd, Christian M. Nefzger, David P. Fairlie, Nathan J. Palpant
Published 2022-05-01

Retrotransposon instability dominates the acquired mutation landscape of mouse induced pluripotent stem cells

by Patricia Gerdes, Sue Mei Lim, Adam D. Ewing, Michael R. Larcombe, Dorothy Chan, Francisco J. Sanchez-Luque, Lucinda Walker, Alexander L. Carleton, Cini James, Anja S. Knaupp, Patricia E. Carreira, Christian M. Nefzger, Ryan Lister, Sandra R. Richardson, Jose M. Polo, Geoffrey J. Faulkner
Published 2022-12-01

Cell Type of Origin Dictates the Route to Pluripotency

by Christian M. Nefzger, Fernando J. Rossello, Joseph Chen, Xiaodong Liu, Anja S. Knaupp, Jaber Firas, Jacob M. Paynter, Jahnvi Pflueger, Sam Buckberry, Sue Mei Lim, Brenda Williams, Sara Alaei, Keshav Faye-Chauhan, Enrico Petretto, Susan K. Nilsson, Ryan Lister, Mirana Ramialison, David R. Powell, Owen J.L. Rackham, Jose M. Polo
Published 2017-12-01

High ploidy large cytoplasmic megakaryocytes are hematopoietic stem cells regulators and essential for platelet production

by Shen Y. Heazlewood, Tanveer Ahmad, Benjamin Cao, Huimin Cao, Melanie Domingues, Xuan Sun, Chad K. Heazlewood, Songhui Li, Brenda Williams, Madeline Fulton, Jacinta F. White, Tom Nebl, Christian M. Nefzger, Jose M. Polo, Benjamin T. Kile, Felix Kraus, Michael T. Ryan, Yu B. Sun, Peter F. M. Choong, Sarah L. Ellis, Minna-Liisa Anko, Susan K. Nilsson
Published 2023-04-01

BAF complex-mediated chromatin relaxation is required for establishment of X chromosome inactivation

by Andrew Keniry, Natasha Jansz, Linden J. Gearing, Iromi Wanigasuriya, Joseph Chen, Christian M. Nefzger, Peter F. Hickey, Quentin Gouil, Joy Liu, Kelsey A. Breslin, Megan Iminitoff, Tamara Beck, Andres Tapia del Fierro, Lachlan Whitehead, Andrew Jarratt, Sarah A. Kinkel, Phillippa C. Taberlay, Tracy Willson, Miha Pakusch, Matthew E. Ritchie, Douglas J. Hilton, Jose M. Polo, Marnie E. Blewitt
Published 2022-03-01

Intestinal stem cell aging signature reveals a reprogramming strategy to enhance regenerative potential

by Christian M. Nefzger, Thierry Jardé, Akanksha Srivastava, Jan Schroeder, Fernando J. Rossello, Katja Horvay, Mirsada Prasko, Jacob M. Paynter, Joseph Chen, Chen-Fang Weng, Yu B. Y. Sun, Xiaodong Liu, Eva Chan, Nikita Deshpande, Xiaoli Chen, Y. Jinhua Li, Jahnvi Pflueger, Rebekah M. Engel, Anja S. Knaupp, Kirill Tsyganov, Susan K. Nilsson, Ryan Lister, Owen J. L. Rackham, Helen E. Abud, Jose M. Polo
Published 2022-06-01

Nicotinamide riboside attenuates age-associated metabolic and functional changes in hematopoietic stem cells

by Xuan Sun, Benjamin Cao, Marina Naval-Sanchez, Tony Pham, Yu Bo Yang Sun, Brenda Williams, Shen Y. Heazlewood, Nikita Deshpande, Jinhua Li, Felix Kraus, James Rae, Quan Nguyen, Hamed Yari, Jan Schröder, Chad K. Heazlewood, Madeline Fulton, Jessica Hatwell-Humble, Kaustav Das Gupta, Ronan Kapetanovic, Xiaoli Chen, Matthew J. Sweet, Robert G. Parton, Michael T. Ryan, Jose M. Polo, Christian M. Nefzger, Susan K. Nilsson
Published 2021-05-01