ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues.

by Mangul, Serghei, Yang, Harry Taegyun, Strauli, Nicolas, Gruhl, Franziska, Porath, Hagit T, Hsieh, Kevin, Chen, Linus, Daley, Timothy, Christenson, Stephanie, Wesolowska-Andersen, Agata, Spreafico, Roberto, Rios, Cydney, Eng, Celeste, Smith, Andrew D, Hernandez, Ryan D, Ophoff, Roel A, Santana, Jose Rodriguez, Levanon, Erez Y, Woodruff, Prescott G, Burchard, Esteban, Seibold, Max A, Shifman, Sagiv, Eskin, Eleazar, Zaitlen, Noah
Published 2018

Molecular programs of fibrotic change in aging human lung.

by Lee, Seoyeon, Islam, Mohammad Naimul, Boostanpour, Kaveh, Aran, Dvir, Jin, Guangchun, Christenson, Stephanie, Matthay, Michael A, Eckalbar, Walter L, DePianto, Daryle J, Arron, Joseph R, Magee, Liam, Bhattacharya, Sunita, Matsumoto, Rei, Kubota, Masaru, Farber, Donna L, Bhattacharya, Jahar, Wolters, Paul J, Bhattacharya, Mallar
Published 2021

Genome-wide association study of lung function and clinical implication in heavy smokers

by Li, Xingnan, Ortega, Victor E., Ampleford, Elizabeth J., Barr, R. Graham, Christenson, Stephanie A., Cooper, Christopher B., Couper, David, Dransfield, Mark T., Han, Mei L. K., Hansel, Nadia N., Hoffman, Eric A., Kanner, Richard E., Kleerup, Eric C., Martinez, Fernando J., Paine, Robert, Woodruff, Prescott G., Hawkins, Gregory A., Bleecker, Eugene R., Meyers, Deborah A., SPIROMICS Research Group
Published 2018

Upper airway gene expression differentiates COVID-19 from other acute respiratory illnesses and reveals suppression of innate immune responses by SARS-CoV-2.

by Mick, Eran, Kamm, Jack, Pisco, Angela Oliveira, Ratnasiri, Kalani, Babik, Jennifer M, Calfee, Carolyn S, Castaneda, Gloria, DeRisi, Joseph L, Detweiler, Angela M, Hao, Samantha, Kangelaris, Kirsten N, Kumar, G Renuka, Li, Lucy M, Mann, Sabrina A, Neff, Norma, Prasad, Priya A, Serpa, Paula Hayakawa, Shah, Sachin J, Spottiswoode, Natasha, Tan, Michelle, Christenson, Stephanie A, Kistler, Amy, Langelier, Charles
Published 2020

Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study

by O’Neal, Wanda, Anderson, Wayne, Basta, Patricia, Carretta, Elizabeth, Doerschuk, Claire, Barr, R. Graham, Bleecker, Eugene, Christenson, Stephanie, Curtis, Jeffrey, Han, Meilan, Hansel, Nadia, Kanner, Richard, Kleerup, Eric, Martinez, Fernando, Miller, Bruce, Peters, Stephen, Rennard, Stephen, Scholand, Mary, Tal-Singer, Ruth, Woodruff, Prescott, Couper, David, Davis, Sonia
Published 2014

Heterogeneous burden of lung disease in smokers with borderline airflow obstruction

by Pirozzi, Cheryl S., Gu, Tian, Quibrera, Pedro M., Carretta, Elizabeth E., Han, MeiLan K., Murray, Susan, Cooper, Christopher B., Tashkin, Donald P., Kleerup, Eric C., Barjaktarevic, Igor, Hoffman, Eric A., Martinez, Carlos H., Christenson, Stephanie A., Hansel, Nadia N., Graham Barr, R., Bleecker, Eugene R., Ortega, Victor E., Martinez, Fernando J., Kanner, Richard E., Paine, Robert
Published 2018

15LO1 dictates glutathione redox changes in asthmatic airway epithelium to worsen type 2 inflammation.

by Nagasaki, Tadao, Schuyler, Alexander, Zhao, Jinming, Samovich, Svetlana, Yamada, Kazuhiro, Deng, Yanhan, Ginebaugh, Scott, Christenson, Stephanie, Woodruff, Prescott, Trudeau, John, Stoyanovsky, Detcho, Ray, Anuradha, Tyurina, Yulia, Kagan, Valerian, Wenzel, Sally, Fahy, John
Published 2022

Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study

by O’Neal, Wanda K., Anderson, Wayne, Basta, Patricia V., Carretta, Elizabeth E., Doerschuk, Claire M., Barr, R. Graham, Bleecker, Eugene R., Christenson, Stephanie A., Curtis, Jeffrey L., Han, Meilan K., Hansel, Nadia N., Kanner, Richard E., Kleerup, Eric C., Martinez, Fernando J., Miller, Bruce E., Peters, Stephen P., Rennard, Stephen I., Scholand, Mary Beth, Tal-Singer, Ruth, Woodruff, Prescott G., Couper, David J., Davis, Sonia M.
Published 2014

Tracheal aspirate RNA sequencing identifies distinct immunological features of COVID-19 ARDS.

by Sarma, Aartik, Christenson, Stephanie A, Byrne, Ashley, Mick, Eran, Pisco, Angela Oliveira, DeVoe, Catherine, Deiss, Thomas, Ghale, Rajani, Zha, Beth Shoshana, Tsitsiklis, Alexandra, Jauregui, Alejandra, Moazed, Farzad, Detweiler, Angela M, Spottiswoode, Natasha, Sinha, Pratik, Neff, Norma, Tan, Michelle, Serpa, Paula Hayakawa, Willmore, Andrew, Ansel, K Mark, Wilson, Jennifer G, Leligdowicz, Aleksandra, Siegel, Emily R, Sirota, Marina, DeRisi, Joseph L, Matthay, Michael A, COMET Consortium, Hendrickson, Carolyn M, Kangelaris, Kirsten N, Krummel, Matthew F, Woodruff, Prescott G, Erle, David J, Calfee, Carolyn S, Langelier, Charles R
Published 2021

COVID-19-related Genes in Sputum Cells in Asthma. Relationship to Demographic Features and Corticosteroids.

by Peters, Michael C, Sajuthi, Satria, Deford, Peter, Christenson, Stephanie, Rios, Cydney L, Montgomery, Michael T, Woodruff, Prescott G, Mauger, David T, Erzurum, Serpil C, Johansson, Mats W, Denlinger, Loren C, Jarjour, Nizar N, Castro, Mario, Hastie, Annette T, Moore, Wendy, Ortega, Victor E, Bleecker, Eugene R, Wenzel, Sally E, Israel, Elliot, Levy, Bruce D, Seibold, Max A, Fahy, John V
Published 2020

Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis.

by Barjaktarevic, Igor Z, Buhr, Russell G, Wang, Xiaoyan, Hu, Scott, Couper, David, Anderson, Wayne, Kanner, Richard E, Paine Iii, Robert, Bhatt, Surya P, Bhakta, Nirav R, Arjomandi, Mehrdad, Kaner, Robert J, Pirozzi, Cheryl S, Curtis, Jeffrey L, O'Neal, Wanda K, Woodruff, Prescott G, Han, MeiLan K, Martinez, Fernando J, Hansel, Nadia, Wells, James Michael, Ortega, Victor E, Hoffman, Eric A, Doerschuk, Claire M, Kim, Victor, Dransfield, Mark T, Drummond, M Bradley, Bowler, Russell, Criner, Gerard, Christenson, Stephanie A, Ronish, Bonnie, Peters, Stephen P, Krishnan, Jerry A, Tashkin, Donald P, Cooper, Christopher B, NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS)
Published 2019

Integrating Host Response and Unbiased Microbe Detection for Lower Respiratory Tract Infection Diagnosis in Critically Ill Adults

by Langelier, Charles, Kalantar, Katrina, Moazed, Farzad, Wilson, Michael, Crawford, Emily, Deiss, Thomas, Belzer, Annika, Bolourchi, Samaneh, Caldera, Saharai, Fung, Monica, Jauregui, Alejandra, Malcolm, Katherine, Lyden, Amy, Khan, Lillian, Vessel, Kathryn, Quan, Jenai, Zinter, Matt, Chiu, Charles, Chow, Eric, Wilson, Jenny, Miller, Steve, Matthay, Michael, Pollard, Katherine, Christenson, Stephanie, Calfee, Carolyn, DeRisi, Joseph
Published 2018

An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup.

by Christenson, Stephanie A, van den Berge, Maarten, Faiz, Alen, Inkamp, Kai, Bhakta, Nirav, Bonser, Luke R, Zlock, Lorna T, Barjaktarevic, Igor Z, Barr, R Graham, Bleecker, Eugene R, Boucher, Richard C, Bowler, Russell P, Comellas, Alejandro P, Curtis, Jeffrey L, Han, MeiLan K, Hansel, Nadia N, Hiemstra, Pieter S, Kaner, Robert J, Krishnanm, Jerry A, Martinez, Fernando J, O'Neal, Wanda K, Paine, Robert, Timens, Wim, Wells, J Michael, Spira, Avrum, Erle, David J, Woodruff, Prescott G
Published 2019

Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD

by Sun, Wei, Kechris, Katerina, Jacobson, Sean, Drummond, M. Bradley, Hawkins, Gregory A., Yang, Jenny, Chen, Ting-huei, Quibrera, Pedro Miguel, Anderson, Wayne, Barr, R. Graham, Basta, Patricia V., Bleecker, Eugene R., Beaty, Terri, Castaldi, Peter, Casaburi, Richard, Cho, Michael H., Comellas, Alejandro, Crapo, James D., Criner, Gerard, Demeo, Dawn, Christenson, Stephanie A., Couper, David J., Doerschuk, Claire M., Curtis, Jeffrey L., Freeman, Christine M., Gouskova, Natalia A., Han, MeiLan K., Hanania, Nicola A., Hansel, Nadia N., Hersh, Craig P., Hoffman, Eric A., Kaner, Robert J., Kanner, Richard E., Kleerup, Eric C., Lutz, Sharon, Martinez, Fernando J., Meyers, Deborah A., Peters, Stephen P., Regan, Elizabeth A., Rennard, Stephen I., Scholand, Mary Beth, Silverman, Edwin K., Woodruff, Prescott G., O’Neal , Wanda K., Bowler, Russell P., SPIROMICS Research Group, COPDGene Investigators
Published 2016

Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD.

by Sun, Wei, Kechris, Katerina, Jacobson, Sean, Drummond, M Bradley, Hawkins, Gregory A, Yang, Jenny, Chen, Ting-Huei, Quibrera, Pedro Miguel, Anderson, Wayne, Barr, R Graham, Basta, Patricia V, Bleecker, Eugene R, Beaty, Terri, Casaburi, Richard, Castaldi, Peter, Cho, Michael H, Comellas, Alejandro, Crapo, James D, Criner, Gerard, Demeo, Dawn, Christenson, Stephanie A, Couper, David J, Curtis, Jeffrey L, Doerschuk, Claire M, Freeman, Christine M, Gouskova, Natalia A, Han, MeiLan K, Hanania, Nicola A, Hansel, Nadia N, Hersh, Craig P, Hoffman, Eric A, Kaner, Robert J, Kanner, Richard E, Kleerup, Eric C, Lutz, Sharon, Martinez, Fernando J, Meyers, Deborah A, Peters, Stephen P, Regan, Elizabeth A, Rennard, Stephen I, Scholand, Mary Beth, Silverman, Edwin K, Woodruff, Prescott G, O'Neal, Wanda K, Bowler, Russell P, SPIROMICS Research Group, COPDGene Investigators
Published 2016

Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium.

by Kasela, Silva, Ortega, Victor E, Martorella, Molly, Garudadri, Suresh, Nguyen, Jenna, Ampleford, Elizabeth, Pasanen, Anu, Nerella, Srilaxmi, Buschur, Kristina L, Barjaktarevic, Igor Z, Barr, R Graham, Bleecker, Eugene R, Bowler, Russell P, Comellas, Alejandro P, Cooper, Christopher B, Couper, David J, Criner, Gerard J, Curtis, Jeffrey L, Han, MeiLan K, Hansel, Nadia N, Hoffman, Eric A, Kaner, Robert J, Krishnan, Jerry A, Martinez, Fernando J, McDonald, Merry-Lynn N, Meyers, Deborah A, Paine, Robert, Peters, Stephen P, Castro, Mario, Denlinger, Loren C, Erzurum, Serpil C, Fahy, John V, Israel, Elliot, Jarjour, Nizar N, Levy, Bruce D, Li, Xingnan, Moore, Wendy C, Wenzel, Sally E, Zein, Joe, NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS), NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Langelier, Charles, Woodruff, Prescott G, Lappalainen, Tuuli, Christenson, Stephanie A
Published 2021

Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD

by Sun, Wei, Kechris, Katerina, Jacobson, Sean, Drummond, M. Bradley, Hawkins, Gregory A., Yang, Jenny, Chen, Ting-huei, Quibrera, Pedro Miguel, Anderson, Wayne, Barr, R. Graham, Basta, Patricia V., Bleecker, Eugene R., Beaty, Terri, Casaburi, Richard, Castaldi, Peter, Cho, Michael H., Comellas, Alejandro, Crapo, James D., Criner, Gerard, Demeo, Dawn, Christenson, Stephanie A., Couper, David J., Curtis, Jeffrey L., Doerschuk, Claire M., Freeman, Christine M., Gouskova, Natalia A., Han, MeiLan K., Hanania, Nicola A., Hansel, Nadia N., Hersh, Craig P., Hoffman, Eric A., Kaner, Robert J., Kanner, Richard E., Kleerup, Eric C., Lutz, Sharon, Martinez, Fernando J., Meyers, Deborah A., Peters, Stephen P., Regan, Elizabeth A., Rennard, Stephen I., Scholand, Mary Beth, Silverman, Edwin K., Woodruff, Prescott G., O’Neal, Wanda K., Bowler, Russell P.
Published 2016