Distinct external signals trigger sequential release of apical organelles during erythrocyte invasion by malaria parasites.

by Shailja Singh, M Mahmood Alam, Ipsita Pal-Bhowmick, Joseph A Brzostowski, Chetan E Chitnis
Published 2010-02-01

Plasmodium falciparum uses gC1qR/HABP1/p32 as a receptor to bind to vascular endothelium and for platelet-mediated clumping.

by Anup Kumar Biswas, Abdul Hafiz, Bhaswati Banerjee, Kwang Sik Kim, Kasturi Datta, Chetan E Chitnis
Published 2007-09-01

Plasmodium falciparum reticulocyte binding-like homologue protein 2 (PfRH2) is a key adhesive molecule involved in erythrocyte invasion.

by Tajali Sahar, K Sony Reddy, Mitasha Bharadwaj, Alok K Pandey, Shailja Singh, Chetan E Chitnis, Deepak Gaur
Published 2011-01-01

The central role of cAMP in regulating Plasmodium falciparum merozoite invasion of human erythrocytes.

by Amrita Dawn, Shailja Singh, Kunal R More, Faiza Amber Siddiqui, Niseema Pachikara, Ghania Ramdani, Gordon Langsley, Chetan E Chitnis
Published 2014-12-01

Comparative recognition by human IgG antibodies of recombinant proteins representing three asexual erythrocytic stage vaccine candidates of Plasmodium vivax

by Mayara B Barbedo, Ricardo Ricci, Maria Carolina S Jimenez, Maristela G Cunha, Syed S Yazdani, Chetan E Chitnis, Mauricio M Rodrigues, Irene S Soares
Published 2007-06-01

Glycan masking of Plasmodium vivax Duffy Binding Protein for probing protein binding function and vaccine development.

by Sowmya Sampath, Chris Carrico, Joel Janes, Sairam Gurumoorthy, Claire Gibson, Martin Melcher, Chetan E Chitnis, Ruobing Wang, William R Schief, Joseph D Smith
Published 2013-01-01

Amplification of Duffy binding protein-encoding gene allows Plasmodium vivax to evade host anti-DBP humoral immunity

by Jean Popovici, Camille Roesch, Lenore L. Carias, Nimol Khim, Saorin Kim, Amelie Vantaux, Ivo Mueller, Chetan E. Chitnis, Christopher L. King, Benoit Witkowski
Published 2020-02-01

Preclinical assessment of viral vectored and protein vaccines targeting the Duffy-binding protein region II of Plasmodium vivax

by Simone C de Cassan, A. Rushdi Shakri, David eLlewellyn, Sean C Elias, Jee Sun Cho, Jee Sun Cho, Anna L Goodman, Jing eJin, Alexander D Douglas, Rossarin eSuwanarusk, Rossarin eSuwanarusk, François H Nosten, Laurent eRénia, Laurent eRénia, Bruce eRussell, Chetan E Chitnis, Chetan E Chitnis, Simon J Draper
Published 2015-07-01

Association of severe malaria outcomes with platelet-mediated clumping and adhesion to a novel host receptor.

by Alfredo Mayor, Abdul Hafiz, Quique Bassat, Eduard Rovira-Vallbona, Sergi Sanz, Sónia Machevo, Ruth Aguilar, Pau Cisteró, Betuel Sigaúque, Clara Menéndez, Pedro L Alonso, Chetan E Chitnis
Published 2011-04-01

cAMP-Dependent Signaling Pathways as Potential Targets for Inhibition of Plasmodium falciparum Blood Stages

by Edwin Lasonder, Kunal More, Shailja Singh, Malak Haidar, Malak Haidar, Daniela Bertinetti, Eileen J. Kennedy, Friedrich W. Herberg, Anthony A. Holder, Gordon Langsley, Gordon Langsley, Chetan E. Chitnis
Published 2021-05-01

Naturally acquired antibody kinetics against Plasmodium vivax antigens in people from a low malaria transmission region in western Thailand

by Zoe Shih-Jung Liu, Jetsumon Sattabongkot, Michael White, Sadudee Chotirat, Chalermpon Kumpitak, Eizo Takashima, Matthias Harbers, Wai-Hong Tham, Julie Healer, Chetan E. Chitnis, Takafumi Tsuboi, Ivo Mueller, Rhea J. Longley
Published 2022-03-01

Phosphorylation-Dependent Assembly of a 14-3-3 Mediated Signaling Complex during Red Blood Cell Invasion by <named-content content-type="genus-species">Plasmodium falciparum</named...

by Kunal R. More, Inderjeet Kaur, Quentin Giai Gianetto, Brandon M. Invergo, Thibault Chaze, Ravi Jain, Christéle Huon, Petra Gutenbrunner, Hendrik Weisser, Mariette Matondo, Jyoti S. Choudhary, Gordon Langsley, Shailja Singh, Chetan E. Chitnis
Published 2020-08-01

Immunogenicity of a Plasmodium vivax vaccine based on the duffy binding protein formulated using adjuvants compatible for use in humans

by Francisco J. Martinez, Micheline Guillotte-Blisnick, Christèle Huon, Patrick England, Jean Popovici, Hélène Laude, Laurence Arowas, Marie-Noëlle Ungeheuer, Jenny M. Reimer, Darrick Carter, Steve Reed, Paushali Mukherjee, Virander S. Chauhan, Chetan E. Chitnis
Published 2023-08-01

Analysis of factors affecting the variability of a quantitative suspension bead array assay measuring IgG to multiple Plasmodium antigens.

by Itziar Ubillos, Ruth Aguilar, Hector Sanz, Alfons Jiménez, Marta Vidal, Aida Valmaseda, Yan Dong, Deepak Gaur, Chetan E Chitnis, Sheetij Dutta, Evelina Angov, John J Aponte, Joseph J Campo, Clarissa Valim, Jaroslaw Harezlak, Carlota Dobaño
Published 2018-01-01

Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target

by Matthias Paulus Wagner, Pauline Formaglio, Olivier Gorgette, Jerzy Michal Dziekan, Christèle Huon, Isabell Berneburg, Stefan Rahlfs, Jean-Christophe Barale, Sheldon I. Feinstein, Aron B. Fisher, Didier Ménard, Zbynek Bozdech, Rogerio Amino, Lhousseine Touqui, Chetan E. Chitnis
Published 2022-06-01

IgM and IgG against Plasmodium falciparum lysate as surrogates of malaria exposure and protection during pregnancy

by Alfredo Mayor, Carlota Dobaño, Augusto Nhabomba, Caterina Guinovart, Alfons Jiménez, Maria Nelia Manaca, Ruth Aguilar, Arnoldo Barbosa, Mauricio H. Rodríguez, Pau Cisteró, Lazaro M. Quimice, Clara Menéndez, John J. Aponte, Jaume Ordi, Chetan E. Chitnis, Pedro L. Alonso
Published 2018-05-01

Genetic diversity in two Plasmodium vivax protein ligands for reticulocyte invasion.

by Camille Roesch, Jean Popovici, Sophalai Bin, Vorleak Run, Saorin Kim, Stéphanie Ramboarina, Emma Rakotomalala, Rado Lalaina Rakotoarison, Tsikiniaina Rasoloharimanana, Zo Andriamanantena, Anuj Kumar, Micheline Guillotte-Blisnick, Christèle Huon, David Serre, Chetan E Chitnis, Inès Vigan-Womas, Didier Menard
Published 2018-10-01

Cytokine and antibody responses to Plasmodium falciparum in naïve individuals during a first malaria episode: effect of age and malaria exposure.

by Gemma Moncunill, Alfredo Mayor, Alfons Jiménez, Augusto Nhabomba, Laura Puyol, Maria N Manaca, Diana Barrios, Pau Cisteró, Caterina Guinovart, Ruth Aguilar, Azucena Bardají, María-Jesús Pinazo, Evelina Angov, Sheetij Dutta, Chetan E Chitnis, José Muñoz, Joaquim Gascón, Carlota Dobaño
Published 2013-01-01

Antibody responses to Plasmodium vivax Duffy binding and Erythrocyte binding proteins predict risk of infection and are associated with protection from clinical Malaria.

by Wen-Qiang He, Ahmad Rushdi Shakri, Rukmini Bhardwaj, Camila T França, Danielle I Stanisic, Julie Healer, Benson Kiniboro, Leanne J Robinson, Micheline Guillotte-Blisnick, Christèle Huon, Peter Siba, Alan Cowman, Christopher L King, Wai-Hong Tham, Chetan E Chitnis, Ivo Mueller
Published 2019-02-01

High antibody responses against Plasmodium falciparum in immigrants after extended periods of interrupted exposure to malaria.

by Gemma Moncunill, Alfredo Mayor, Alfons Jiménez, Augusto Nhabomba, Núria Casas-Vila, Laura Puyol, Joseph J Campo, Maria Nelia Manaca, Ruth Aguilar, María-Jesús Pinazo, Mercè Almirall, Cristina Soler, José Muñoz, Azucena Bardají, Evelina Angov, Sheetij Dutta, Chetan E Chitnis, Pedro L Alonso, Joaquim Gascón, Carlota Dobaño
Published 2013-01-01