The second transmembrane domain of P2X7 contributes to dilated pore formation.

by Chengqun Sun, Michelle E Heid, Peter A Keyel, Russell D Salter
Published 2013-01-01

Detailed topology mapping reveals substantial exposure of the "cytoplasmic" C-terminal tail (CTT) sequences in HIV-1 Env proteins at the cell surface.

by Jonathan D Steckbeck, Chengqun Sun, Timothy J Sturgeon, Ronald C Montelaro
Published 2013-01-01

Topology of the C-terminal tail of HIV-1 gp41: differential exposure of the Kennedy epitope on cell and viral membranes.

by Jonathan D Steckbeck, Chengqun Sun, Timothy J Sturgeon, Ronald C Montelaro
Published 2010-12-01

Rational design of a live-attenuated eastern equine encephalitis virus vaccine through informed mutation of virulence determinants.

by Derek W Trobaugh, Chengqun Sun, Matthew D Dunn, Douglas S Reed, William B Klimstra
Published 2019-02-01

Cooperativity between the 3' untranslated region microRNA binding sites is critical for the virulence of eastern equine encephalitis virus.

by Derek W Trobaugh, Chengqun Sun, Nishank Bhalla, Christina L Gardner, Matthew D Dunn, William B Klimstra
Published 2019-10-01

The Interferon-Induced Exonuclease ISG20 Exerts Antiviral Activity through Upregulation of Type I Interferon Response Proteins

by Christopher M. Weiss, Derek W. Trobaugh, Chengqun Sun, Tiffany M. Lucas, Michael S. Diamond, Kate D. Ryman, William B. Klimstra
Published 2018-10-01

Venezuelan Equine Encephalitis Virus nsP3 Phosphorylation Can Be Mediated by IKKβ Kinase Activity and Abrogation of Phosphorylation Inhibits Negative-Strand Synthesis

by Allison Bakovic, Nishank Bhalla, Stephanie Kortchak, Chengqun Sun, Weidong Zhou, Aslaa Ahmed, Kenneth Risner, William B. Klimstra, Aarthi Narayanan
Published 2020-09-01

Encephalitic Alphaviruses Exploit Caveola-Mediated Transcytosis at the Blood-Brain Barrier for Central Nervous System Entry

by Hamid Salimi, Matthew D. Cain, Xiaoping Jiang, Robyn A. Roth, Wandy L. Beatty, Chengqun Sun, William B. Klimstra, Jianghui Hou, Robyn S. Klein
Published 2020-02-01

Deliberate attenuation of chikungunya virus by adaptation to heparan sulfate-dependent infectivity: a model for rational arboviral vaccine design.

by Christina L Gardner, Jozef Hritz, Chengqun Sun, Dana L Vanlandingham, Timothy Y Song, Elodie Ghedin, Stephen Higgs, William B Klimstra, Kate D Ryman
Published 2014-02-01

In Vitro and In Vivo Phenotypes of Venezuelan, Eastern and Western Equine Encephalitis Viruses Derived from cDNA Clones of Human Isolates

by Christina L. Gardner, Chengqun Sun, Matthew D. Dunn, Theron C. Gilliland, Derek W. Trobaugh, Yutaka Terada, Douglas S. Reed, Amy L. Hartman, William B. Klimstra
Published 2022-12-01

Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization

by S. Saif Hasan, Chengqun Sun, Arthur S. Kim, Yasunori Watanabe, Chun-Liang Chen, Thomas Klose, Geeta Buda, Max Crispin, Michael S. Diamond, William B. Klimstra, Michael G. Rossmann
Published 2018-12-01

Ribbon scanning confocal for high-speed high-resolution volume imaging of brain.

by Alan M Watson, Annika H Rose, Gregory A Gibson, Christina L Gardner, Chengqun Sun, Douglas S Reed, L K Metthew Lam, Claudette M St Croix, Peter L Strick, William B Klimstra, Simon C Watkins
Published 2017-01-01