Patterns of glucose hypometabolism in Down syndrome resemble sporadic Alzheimer's disease except for the putamen

by Matthew D. Zammit, Charles M. Laymon, Dana L. Tudorascu, Sigan L. Hartley, Brianna Piro‐Gambetti, Sterling C. Johnson, Charles K. Stone, Chester A. Mathis, Shahid H. Zaman, William E. Klunk, Benjamin L. Handen, Ann D. Cohen, Bradley T. Christian
Published 2020-01-01

PET measurement of longitudinal amyloid load identifies the earliest stages of amyloid-beta accumulation during Alzheimer's disease progression in Down syndrome

by Matthew D. Zammit, Dana L. Tudorascu, Charles M. Laymon, Sigan L. Hartley, Shahid H. Zaman, Beau M. Ances, Sterling C. Johnson, Charles K. Stone, Chester A. Mathis, William E. Klunk, Ann D. Cohen, Benjamin L. Handen, Bradley T. Christian
Published 2021-03-01

Amyloid duration is associated with preclinical cognitive decline and tau PET

by Rebecca L. Koscik, Tobey J. Betthauser, Erin M. Jonaitis, Samantha L. Allison, Lindsay R. Clark, Bruce P. Hermann, Karly A. Cody, Jonathan W. Engle, Todd E. Barnhart, Charles K. Stone, Nathaniel A. Chin, Cynthia M. Carlsson, Sanjay Asthana, Bradley T. Christian, Sterling C. Johnson
Published 2020-01-01

Neurofibrillary tau depositions emerge with subthreshold cerebral beta-amyloidosis in down syndrome

by Matthew D. Zammit, Dana L. Tudorascu, Charles M. Laymon, Sigan L. Hartley, Paul A. Ellison, Shahid H. Zaman, Beau M. Ances, Sterling C. Johnson, Charles K. Stone, Marwan N. Sabbagh, Chester A. Mathis, William E. Klunk, Ann D. Cohen, Benjamin L. Handen, Bradley T. Christian
Published 2021-01-01