The Metamorphic Nature of the Tau Protein: Dynamic Flexibility Comes at a Cost

by Jonathan J Sabbagh, Chad A Dickey
Published 2016-01-01

Hippocampal Neurogenesis Is Enhanced in Adult Tau Deficient Mice

by Marangelie Criado-Marrero, Jonathan J. Sabbagh, Margaret R. Jones, Dale Chaput, Chad A. Dickey, Laura J. Blair
Published 2020-01-01

Suppression of galactosylceramidase (GALC) expression in the twitcher mouse model of globoid cell leukodystrophy (GLD) is caused by nonsense-mediated mRNA decay (NMD)

by Wing C. Lee, Yuen K. Tsoi, Chad A. Dickey, Michael W. DeLucia, Dennis W. Dickson, Christopher B. Eckman
Published 2006-08-01

Early Life Stress and High FKBP5 Interact to Increase Anxiety-Like Symptoms through Altered AKT Signaling in the Dorsal Hippocampus

by Marangelie Criado-Marrero, Niat T. Gebru, Lauren A. Gould, Taylor M. Smith, Sojeong Kim, Roy J. Blackburn, Chad A. Dickey, Laura J. Blair
Published 2019-06-01

Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency.

by Jonathan J Sabbagh, John C O'Leary, Laura J Blair, Torsten Klengel, Bryce A Nordhues, Sarah N Fontaine, Elisabeth B Binder, Chad A Dickey
Published 2014-01-01

FKBP5 and early life stress affect the hippocampus by an age-dependent mechanism

by Marangelie Criado-Marrero, Taylor M. Smith, Lauren A. Gould, Sojeong Kim, Hannah J. Penny, Zheying Sun, Danielle Gulick, Chad A. Dickey, Laura J. Blair
Published 2020-12-01

Correction: Rhodacyanine Derivative Selectively Targets Cancer Cells and Overcomes Tamoxifen Resistance.

by John Koren, Yoshinari Miyata, Janine Kiray, John C. O'Leary, Lana Nguyen, Jianping Guo, Laura J. Blair, Xiaokai Li, Umesh K. Jinwal, Jin Q. Cheng, Jason E. Gestwicki, Chad A. Dickey
Published 2012-01-01

Rhodacyanine derivative selectively targets cancer cells and overcomes tamoxifen resistance.

by John Koren, Yoshinari Miyata, Janine Kiray, John C O'Leary, Lana Nguyen, Jianping Guo, Laura J Blair, Xiaokai Li, Umesh K Jinwal, Jin Q Cheng, Jason E Gestwicki, Chad A Dickey
Published 2012-01-01

A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51.

by John C O'Leary, Sheetal Dharia, Laura J Blair, Sarah Brady, Amelia G Johnson, Melinda Peters, Joyce Cheung-Flynn, Marc B Cox, Gabriel de Erausquin, Edwin J Weeber, Umesh K Jinwal, Chad A Dickey
Published 2011-01-01

Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex

by Javier Oroz, Bliss J. Chang, Piotr Wysoczanski, Chung-Tien Lee, Ángel Pérez-Lara, Pijush Chakraborty, Romina V. Hofele, Jeremy D. Baker, Laura J. Blair, Jacek Biernat, Henning Urlaub, Eckhard Mandelkow, Chad A. Dickey, Markus Zweckstetter
Published 2018-10-01

FKBP52 overexpression accelerates hippocampal-dependent memory impairments in a tau transgenic mouse model

by Marangelie Criado-Marrero, Niat T. Gebru, Lauren A. Gould, Danielle M. Blazier, Yamile Vidal-Aguiar, Taylor M. Smith, Salma S. Abdelmaboud, Lindsey B. Shelton, Xinming Wang, Jan Dahrendorff, David Beaulieu-Abdelahad, Chad A. Dickey, Laura J. Blair
Published 2021-05-01

Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels

by Jack M. Webster, April L. Darling, Taylor A. Sanders, Danielle M. Blazier, Yamile Vidal-Aguiar, David Beaulieu-Abdelahad, Drew G. Plemmons, Shannon E. Hill, Vladimir N. Uversky, Paula C. Bickford, Chad A. Dickey, Laura J. Blair
Published 2020-07-01

Small Heat Shock Protein 22 Improves Cognition and Learning in the Tauopathic Brain

by Santiago Rodriguez Ospina, Danielle M. Blazier, Marangelie Criado-Marrero, Lauren A. Gould, Niat T. Gebru, David Beaulieu-Abdelahad, Xinming Wang, Elizabeth Remily-Wood, Dale Chaput, Stanley Stevens, Vladimir N. Uversky, Paula C. Bickford, Chad A. Dickey, Laura J. Blair
Published 2022-01-01

Human cyclophilin 40 unravels neurotoxic amyloids.

by Jeremy D Baker, Lindsey B Shelton, Dali Zheng, Filippo Favretto, Bryce A Nordhues, April Darling, Leia E Sullivan, Zheying Sun, Parth K Solanki, Mackenzie D Martin, Amirthaa Suntharalingam, Jonathan J Sabbagh, Stefan Becker, Eckhard Mandelkow, Vladimir N Uversky, Markus Zweckstetter, Chad A Dickey, John Koren, Laura J Blair
Published 2017-06-01

Spermidine/spermine-N 1-acetyltransferase ablation impacts tauopathy-induced polyamine stress response

by Leslie A. Sandusky-Beltran, Andrii Kovalenko, Chao Ma, John Ivan T. Calahatian, Devon S. Placides, Mallory D. Watler, Jerry B. Hunt, April L. Darling, Jeremy D. Baker, Laura J. Blair, Mackenzie D. Martin, Sarah N. Fontaine, Chad A. Dickey, April L. Lussier, Edwin J. Weeber, Maj-Linda B. Selenica, Kevin R. Nash, Marcia N. Gordon, Dave Morgan, Daniel C. Lee
Published 2019-06-01