Viral quasispecies.

by Esteban Domingo, Celia Perales
Published 2019-10-01

Counteracting quasispecies adaptability: extinction of a ribavirin-resistant virus mutant by an alternative mutagenic treatment.

by Celia Perales, Rubén Agudo, Esteban Domingo
Published 2009-01-01

Deletion mutants of VPg reveal new cytopathology determinants in a picornavirus.

by Armando Arias, Celia Perales, Cristina Escarmís, Esteban Domingo
Published 2010-01-01

Mutation Rates, Mutation Frequencies, and Proofreading-Repair Activities in RNA Virus Genetics

by Esteban Domingo, Carlos García-Crespo, Rebeca Lobo-Vega, Celia Perales
Published 2021-09-01

Resistance of Hepatitis C Virus to Inhibitors: Complexity and Clinical Implications

by Celia Perales, Josep Quer, Josep Gregori, Juan Ignacio Esteban, Esteban Domingo
Published 2015-11-01

Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections.

by Celia Perales, Rubén Agudo, Hector Tejero, Susanna C Manrubia, Esteban Domingo
Published 2009-11-01

Efficacy decrease of antiviral agents when administered to ongoing hepatitis C virus infections in cell culture

by Carlos García-Crespo, Carlos García-Crespo, Lucía Vázquez-Sirvent, Lucía Vázquez-Sirvent, Pilar Somovilla, Pilar Somovilla, María Eugenia Soria, María Eugenia Soria, María Eugenia Soria, Isabel Gallego, Isabel Gallego, Ana Isabel de Ávila, Ana Isabel de Ávila, Brenda Martínez-González, Brenda Martínez-González, Antoni Durán-Pastor, Esteban Domingo, Esteban Domingo, Celia Perales, Celia Perales, Celia Perales, Celia Perales
Published 2022-08-01

Hepatitis C virus fitness can influence the extent of infection-mediated epigenetic modifications in the host cells

by Carlos García-Crespo, Carlos García-Crespo, Irene Francisco-Recuero, Isabel Gallego, Isabel Gallego, Marina Camblor-Murube, María Eugenia Soria, María Eugenia Soria, María Eugenia Soria, Ana López-López, Ana Isabel de Ávila, Ana Isabel de Ávila, Antonio Madejón, Antonio Madejón, Javier García-Samaniego, Javier García-Samaniego, Esteban Domingo, Esteban Domingo, Aurora Sánchez-Pacheco, Celia Perales, Celia Perales, Celia Perales
Published 2023-03-01

Akt Phosphorylation of Hepatitis C Virus NS5B Regulates Polymerase Activity and Hepatitis C Virus Infection

by Rosario Sabariegos, Rosario Sabariegos, Rosario Sabariegos, Laura Albentosa-González, Blanca Palmero, Pilar Clemente-Casares, Pilar Clemente-Casares, Pilar Clemente-Casares, Eugenio Ramírez, Carlos García-Crespo, Carlos García-Crespo, Isabel Gallego, Isabel Gallego, Ana Isabel de Ávila, Ana Isabel de Ávila, Celia Perales, Celia Perales, Celia Perales, Esteban Domingo, Esteban Domingo, Esteban Domingo, Antonio Mas, Antonio Mas, Antonio Mas
Published 2021-10-01

Viral genome segmentation can result from a trade-off between genetic content and particle stability.

by Samuel Ojosnegros, Juan García-Arriaza, Cristina Escarmís, Susanna C Manrubia, Celia Perales, Armando Arias, Mauricio García Mateu, Esteban Domingo
Published 2011-03-01

Rare haplotype load as marker for lethal mutagenesis.

by Josep Gregori, María Eugenia Soria, Isabel Gallego, Mercedes Guerrero-Murillo, Juan Ignacio Esteban, Josep Quer, Celia Perales, Esteban Domingo
Published 2018-01-01

A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.

by Rubén Agudo, Cristina Ferrer-Orta, Armando Arias, Ignacio de la Higuera, Celia Perales, Rosa Pérez-Luque, Nuria Verdaguer, Esteban Domingo
Published 2010-08-01

Extinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesis.

by Ana M Ortega-Prieto, Julie Sheldon, Ana Grande-Pérez, Héctor Tejero, Josep Gregori, Josep Quer, Juan I Esteban, Esteban Domingo, Celia Perales
Published 2013-01-01

Lethal Mutagenesis of Hepatitis C Virus Induced by Favipiravir.

by Ana I de Ávila, Isabel Gallego, Maria Eugenia Soria, Josep Gregori, Josep Quer, Juan Ignacio Esteban, Charles M Rice, Esteban Domingo, Celia Perales
Published 2016-01-01

Ultra-deep pyrosequencing (UDPS) data treatment to study amplicon HCV minor variants.

by Josep Gregori, Juan I Esteban, María Cubero, Damir Garcia-Cehic, Celia Perales, Rosario Casillas, Miguel Alvarez-Tejado, Francisco Rodríguez-Frías, Jaume Guardia, Esteban Domingo, Josep Quer
Published 2013-01-01

Study of Quasispecies Complexity and Liver Damage Progression after Liver Transplantation in Hepatitis C Virus Infected Patients

by Meritxell Llorens-Revull, Josep Gregori, Cristina Dopazo, Francisco Rodriguez-Frías, Damir Garcia-Cehic, Maria Eugenia Soria, Qian Chen, Ariadna Rando, Celia Perales, Juan Ignacio Esteban, Josep Quer, Itxarone Bilbao
Published 2021-10-01

A Two-Level, Intramutant Spectrum Haplotype Profile of Hepatitis C Virus Revealed by Self-Organized Maps

by Soledad Delgado, Celia Perales, Carlos García-Crespo, María Eugenia Soria, Isabel Gallego, Ana Isabel de Ávila, Brenda Martínez-González, Lucía Vázquez-Sirvent, Cecilio López-Galíndez, Federico Morán, Esteban Domingo
Published 2021-12-01

Dissimilar Conservation Pattern in Hepatitis C Virus Mutant Spectra, Consensus Sequences, and Data Banks

by Carlos García-Crespo, María Eugenia Soria, Isabel Gallego, Ana Isabel de Ávila, Brenda Martínez-González, Lucía Vázquez-Sirvent, Jordi Gómez, Carlos Briones, Josep Gregori, Josep Quer, Celia Perales, Esteban Domingo
Published 2020-10-01

SARS-CoV-2 mutant spectra as variant of concern nurseries: endless variation?

by Brenda Martínez-González, Brenda Martínez-González, María Eugenia Soria, María Eugenia Soria, Pablo Mínguez, Pablo Mínguez, Pablo Mínguez, Ramón Lorenzo-Redondo, Llanos Salar-Vidal, Llanos Salar-Vidal, Alberto López-García, Mario Esteban-Muñoz, Antoni Durán-Pastor, Pilar Somovilla, Pilar Somovilla, Carlos García-Crespo, Ana Isabel de Ávila, Jordi Gómez, Jaime Esteban, Jaime Esteban, Ricardo Fernández-Roblas, Ricardo Fernández-Roblas, Ignacio Gadea, Ignacio Gadea, Esteban Domingo, Celia Perales, Celia Perales
Published 2024-03-01

An Efficient Microarray-Based Genotyping Platform for the Identification of Drug-Resistance Mutations in Majority and Minority Subpopulations of HIV-1 Quasispecies.

by Verónica Martín, Celia Perales, María Fernández-Algar, Helena G Dos Santos, Patricia Garrido, María Pernas, Víctor Parro, Miguel Moreno, Javier García-Pérez, José Alcamí, José Luis Torán, David Abia, Esteban Domingo, Carlos Briones
Published 2016-01-01