Carl-Henrik Heldin

Carl-Henrik Heldin (born 9 August 1952) is Chairman of the Board for the Nobel Foundation, and a molecular biologist and medical researcher. He has been director of the Uppsala branch of Ludwig Cancer Research since 1986 and professor in molecular cell biology at the medical faculty of Uppsala University since 1992. He is vice-president of the European Research Council since 2011 and was appointed chairman of the Nobel Foundation in 2013.

His research has focused on the mechanisms of signal transduction by growth regulatory factors like platelet-derived growth factor (PDGF) and transforming growth factor (TGF). He was senior editor of Cancer Research from 2003 to 2009. Provided by Wikipedia
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  1. 1
    Mechanisms of TGFβ-Induced Epithelial–Mesenchymal Transition
    by Aristidis Moustakas, Carl-Henrik Heldin
    Published 2016-06-01
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  2. 2
    The E3 Ubiquitin Ligase TRIM21 Regulates Basal Levels of PDGFRβ
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  3. 3
    NR4A1 promotes PDGF-BB-induced cell colony formation in soft agar.
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  4. 4
    Tumor Promoting Effect of BMP Signaling in Endometrial Cancer
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  5. 5
    SUMOylation of PDGF receptor α affects signaling via PLCγ and STAT3, and cell proliferation
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  6. 6
    Genomewide binding of transcription factor Snail1 in triple‐negative breast cancer cells
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  7. 7
    TRAF4/6 Is Needed for CD44 Cleavage and Migration via RAC1 Activation
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  8. 8
    Loss of SNAI1 induces cellular plasticity in invasive triple-negative breast cancer cells
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  9. 9
    CD44 Depletion in Glioblastoma Cells Suppresses Growth and Stemness and Induces Senescence
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  10. 10
    Extracellular Vesicles and Transforming Growth Factor β Signaling in Cancer
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  11. 11
    Smad7 Enhances TGF-β-Induced Transcription of c-Jun and HDAC6 Promoting Invasion of Prostate Cancer Cells
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  12. 12
    Identification of a Small Molecule Inhibitor of Hyaluronan Synthesis, DDIT, Targeting Breast Cancer Cells
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  13. 13
    The long non-coding RNA LINC00707 interacts with Smad proteins to regulate TGFβ signaling and cancer cell invasion
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  14. 14
    The TGFB2-AS1 lncRNA Regulates TGF-β Signaling by Modulating Corepressor Activity
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  15. 15
    High levels of serum hyaluronan is an early predictor of dengue warning signs and perturbs vascular integrityResearch in context
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  16. 16
    Expression of Platelet-Derived Growth Factor in and around Intrastriatal Embryonic Mesencephalic Grafts
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  17. 17
    Hyaluronan-Induced CD44-iASPP Interaction Affects Fibroblast Migration and Survival
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  18. 18
    Combined anti-angiogenic therapy targeting PDGF and VEGF receptors lowers the interstitial fluid pressure in a murine experimental carcinoma.
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  19. 19
    BMP Sustains Embryonic Stem Cell Self-Renewal through Distinct Functions of Different Krüppel-like Factors
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  20. 20
    PRRX1 induced by BMP signaling decreases tumorigenesis by epigenetically regulating glioma‐initiating cell properties via DNA methyltransferase 3A
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