Murine Models of Lysosomal Storage Diseases Exhibit Differences in Brain Protein Aggregation and Neuroinflammation

by Jennifer Clarke, Can Kayatekin, Catherine Viel, Lamya Shihabuddin, Sergio Pablo Sardi
Published 2021-04-01

Metal-free ALS variants of dimeric human Cu,Zn-superoxide dismutase have enhanced populations of monomeric species.

by Anna-Karin E Svensson, Osman Bilsel, Can Kayatekin, Jessica A Adefusika, Jill A Zitzewitz, C Robert Matthews
Published 2010-04-01

Preclinical pharmacology of glucosylceramide synthase inhibitor venglustat in a GBA-related synucleinopathy model

by Catherine Viel, Jennifer Clarke, Can Kayatekin, Amy M. Richards, Ming Sum R. Chiang, Hyejung Park, Bing Wang, Lamya S. Shihabuddin, S. Pablo Sardi
Published 2021-10-01

Persistent Activation of mRNA Translation by Transient Hsp90 Inhibition

by Peter Tsvetkov, Timothy J. Eisen, Sven U. Heinrich, Zarina Brune, Erinc Hallacli, Greg A. Newby, Can Kayatekin, David Pincus, Susan Lindquist
Published 2020-08-01

Identification of human monoclonal antibodies specific for human SOD1 recognizing distinct epitopes and forms of SOD1.

by Teresa J Broering, Hongyan Wang, Naomi K Boatright, Yang Wang, Katherine Baptista, Gilda Shayan, Kerry A Garrity, Can Kayatekin, Daryl A Bosco, C Robert Matthews, Donna M Ambrosino, Zuoshang Xu, Gregory J Babcock
Published 2013-01-01

Evaluation of Neurofilament Light Chain as a Biomarker of Neurodegeneration in X-Linked Childhood Cerebral Adrenoleukodystrophy

by Hongge Wang, Matthew D. Davison, Martin L. Kramer, Weiliang Qiu, Tatiana Gladysheva, Ruby M. S. Chiang, Can Kayatekin, David R. Nascene, Leyla A. Taghizadeh, Carina J. King, Erin E. Nolan, Ashish O. Gupta, Paul J. Orchard, Troy C. Lund
Published 2022-03-01

Isolation, Characterization, and Aggregation of a Structured Bacterial Matrix Precursor

by Chai, Liraz, Romero, Diego, Kayatekin, Can, Akabayov, Barak, Vlamakis, Hera, Losick, Richard, Kolter, Roberto
Published 2019

Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition

by Taipale, Mikko, Krykbaeva, Irina, Kayatekin, Can, Westover, Kenneth D., Karras, Georgios I., Lindquist, Susan, Koeva, Martina I
Published 2014

Distinct Prion Strains Are Defined by Amyloid Core Structure and Chaperone Binding Site Dynamics

by Frederick, Kendra K., Debelouchina, Galia Tzvetanova, Kayatekin, Can, Dorminy, Tea, Jacavone, Angela, Griffin, Robert Guy, Lindquist, Susan
Published 2016