P497: PROGNOSTIC IMPACT OF RAS AND C-KIT MUTATIONS (SINGLE VS. MULTIPLE) IN CORE-BINDING FACTOR ACUTE MYELOID LEUKEMIA TREATED WITH FLUDARABINE, CYTARABINE, G-CSF (FLAG) BASED REGI...

by T. Abuasab, J. Senapati, T. Kadia, F. Ravandi, C. DiNardo, N. Pemmaraju, M. Ohanion, Y. Alvarado, H. Kantarjian, G. Borthakur
Published 2022-06-01

P575: IMPACT OF MOLECULAR RESPONSE AND CHEMOTHERAPY REGIMEN ON OUTCOMES IN CORE BINDING FACTOR AML

by J. Senapati, F. Haddad, F. Ravandi, T. Kadia, C. DiNardo, N. Daver, N. Pemmaraju, Y. Alvarado, M. A. Brandt, H. Kantarjian, G. Borthakur
Published 2022-06-01

PB1831: UTILITY OF FLT3 INHIBITORS IN PATIENTS WITH ACUTE MYELOID LEUKEMIA (AML) AND T(6;9)(P22;Q34)

by F. Ong, T. M. Kadia, N. J. Short, M. Yilmaz, Y. Alvarado, S. Pierce, G. Garcia-Manero, C. DiNardo, G. Borthakur, M. Konopleva, N. Daver, H. Kantarjian, F. Ravandi
Published 2022-06-01

P496: CLINICAL CHARACTERISTICS OF SECONDARY MYELOID NEOPLASMS IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE

by T. Abuasab, S. F. Mohadam, H. Hwang, X. Wang, K. Sasaki, M. Yilmaz, T. Kadia, C. DiNardo, N. Daver, N. Pemmaraju, G. Borthakur, F. Ravandi, G. Garcia-Manero, K. Takahashi
Published 2022-06-01

P510: THE IMPACT OF POST-REMISSION GRANULOCYTE COLONY-STIMULATING FACTOR USE IN THE PHASE 3 STUDIES OF VENETOCLAX COMBINATION TREATMENTS IN PATIENTS WITH NEWLY DIAGNOSED ACUTE MYEL...

by C. DiNardo, K. Pratz, P. Panayiotidis, X. Wei, V. Vorobyev, Á. Illés, I. Kim, V. Ivanov, G. Ku, C. L. Miller, M. Zhang, F. Tatsch, J. Potluri, X. Schmidt, C. Recher
Published 2022-06-01

P506: ACHIEVEMENT OF MEASURABLE RESIDUAL DISEASE CLEARANCE IS A STRONGER PREDICTOR OF PATIENT OUTCOME THAN TREATMENT INTENSITY IN NEWLY DIAGNOSED PATIENTS WITH ACUTE MYELOID LEUKEM...

by A. Bazinet, T. Kadia, N. Short, G. Borthakur, S. Wang, S. Loghavi, J. Jorgensen, K. Patel, C. DiNardo, N. Daver, Y. Alvarado, F. Haddad, S. Pierce, M. Andreeff, E. Jabbour, M. Konopleva, H. Kantarjian, F. Ravandi
Published 2022-06-01

P430: MOLECULAR CHARACTERIZATION OF CLINICAL RESPONSE IN NEWLY-DIAGNOSED ACUTE MYELOID LEUKEMIA PATIENTS TREATED WITH IVOSIDENIB + AZACITIDINE COMPARED TO PLACEBO + AZACITIDINE

by S. de Botton, S. Choe, D. Marchione, P. Montesinos, C. Recher, S. Vives Polo, E. Zarzycka, J. Wang, G. Bertani, M. Heuser, R. Calado, A. Schuh, S.-P. Yeh, J. Hui, S. Pandya, D. Gianolio, S. Daigle, C. DiNardo, H. Dohner
Published 2022-06-01

P495: PHASE 2 STUDY OF ASTX727 (DECITABINE/CEDAZURIDINE) PLUS VENETOCLAX IN PATIENTS WITH RELAPSED/REFRACTORY ACUTE MYELOID LEUKEMIA (AML) OR PREVIOUSLY UNTREATED, ELDERLY PATIENTS...

by T. Abuasab, Y. Alvarado, G. Issa, R. Islam, N. Short, M. Yilmaz, N. jain, L. Masarova, S. Kornblau, E. Jabbour, N. Pemmaraju, G. Montalban-Bravo, S. Pierce, C. DiNardo, T. Kadia, N. Daver, M. Konopleva, G. Garcia-Manero, F. Ravandi
Published 2022-06-01

S127: QUIZARTINIB WITH DECITABINE AND VENETOCLAX (TRIPLET) IS ACTIVE IN PATIENTS WITH FLT3-ITD MUTATED ACUTE MYELOID LEUKEMIA - A PHASE I/II STUDY

by M. Yilmaz, M. Muftuoglu, H. Kantarjian, C. DiNardo, T. Kadia, G. Borthakur, N. Pemmaraju, N. Short, Y. Alvarado, A. Maiti, L. Masarova, G. Montalban Bravo, S. Loghavi, K. Patel, S. Kornblau, E. Jabbour, G. Garcia-Manero, M. Andreeff, N. Daver
Published 2022-06-01

P541: OUTCOMES AND MANAGEMENT OF PATIENTS WITH NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA PRESENTING WITH HYPERLEUKOCYTOSIS

by F. Haddad, K. Sasaki, T. Abuasab, S. Venugopal, D. Rivera Delgado, A. Bazinet, R. Babakhanlou, K. Kim, J. Senapati, F. Ong, S. Desikan, N. Short, N. Pemmaraju, G. Borthakur, C. DiNardo, N. Daver, E. Jabbour, G. Garcia-Manero, F. Ravandi, T. Kadia
Published 2022-06-01

P590: PRELIMINARY SAFETY AND EFFICACY OF BGB-11417, A POTENT AND SELECTIVE B-CELL LYMPHOMA 2 (BCL2) INHIBITOR, IN PATIENTS (PTS) WITH ACUTE MYELOID LEUKEMIA (AML)

by J. Shortt, S. Y. Tan, P. Cannell, T. F. Ng, C. Y. Fong, S. Ramanathan, R. Rajagopal, S. Leitch, R. Gasiorowski, C. Grove, D. Lenton, P. Tan, C. DiNardo, M. T. Ling, S. Cheng, Y. Liu, M. Co, W. Y. Chan, D. Simpson, A. H. Wei
Published 2022-06-01

P576: A PHASE I/II STUDY OF MILADEMETAN (DS3032B) IN COMBINATION WITH LOW DOSE CYTARABINE WITH OR WITHOUT VENETOCLAX IN ACUTE MYELOID LEUKEMIA

by J. Senapati, J. Ishizawa, H. A. Abbas, S. Loghavi, G. Borthakur, G. C. Issa, S. I. Dara, R. Pourebrahim, N. Daver, E. J. Jabbour, S. M. Kornblau, N. Pemmaraju, G. Garcia-Manero, F. Ravandi, M. Muftuoglu, J. Khoury, C. DiNardo, M. Andreeff
Published 2022-06-01

P355: MINI-HYPER-CVD PLUS INOTUZUMAB OZOGAMICIN, WITH OR WITHOUT BLINATUMOMAB, IN OLDER ADULTS WITH NEWLY DIAGNOSED B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA: UPDATES FROM A PHASE II TRI...

by F. Haddad, H. Kantarjian, N. Short, F. Ravandi, N. Jain, W. Macaron, T. Kadia, Y. Alvarado, N. Daver, G. Borthakur, C. DiNardo, M. Konopleva, W. Wierda, J. Jacob, E. Roy, C. Loiselle, A. Milton, J. Rivera, R. Garris, E. Jabbour
Published 2022-06-01

P368: A PHASE II STUDY OF INOTUZUMAB OZOGAMICIN FOR THE TREATMENT OF MEASURABLE RESIDUAL DISEASE-POSITIVE B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA

by J. Senapati, H. Kantarjian, N. Short, Y. Alvarado, J. Burger, N. Jain, M. Konopleva, F. Ravandi, C. DiNardo, L. Masarova, K. Sasaki, P. A. Thompson, A. Ferrajoli, J. O. Jacob, E. D. Mayor, A. M. Milton, C. Loiselle, R. S. Garris, E. J. Jabbour
Published 2022-06-01

P566: IMPACT OF FRONTLINE INDUCTION APPROACH ON POST-STEM CELL TRANSPLANT (SCT) OUTCOMES IN OLDER ADULTS WITH NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA (AML)

by F. Ong, F. Ravandi, U. Popat, T. M. Kadia, N. Daver, C. DiNardo, M. Konopleva, G. Borthakur, E. J. Shpall, B. Oran, G. Al-Atrash, R. Mehta, E. J. Jabbour, M. Yilmaz, G. C. Issa, G. Garcia-Manero, A. Maiti, H. A. Abbas, R. E. Champlin, N. J. Short
Published 2022-06-01

P757: RESULTS OF A PHASE 1 STUDY OF AZACITIDINE COMBINED WITH VENETOCLAX FOR TREATMENT-NAIVE AND RELAPSED HIGH-RISK MYELODYSPLASTIC SYNDROME AND CHRONIC MYELOMONOCYTIC LEUKEMIA

by A. Bazinet, E. Jabbour, H. Kantarjian, K. Chien, C. DiNardo, M. Ohanian, N. Daver, R. Kanagal-Shamanna, T. Kadia, K. Takahashi, L. Masarova, N. Short, Y. Alvarado, P. Thompson, G. Montalban-Bravo, M. Yilmaz, F. Ravandi, M. Konopleva, M. Andreeff, S. Kornblau, N. Pemmaraju, D. Hammond, H. Schneider, B. Mirabella, G. Garcia-Manero
Published 2022-06-01

Choroid-Plexus-Derived Otx2 Homeoprotein Constrains Adult Cortical Plasticity

by Spatazza, Julien, Lee, Henry H.C., Di Nardo, Ariel A., Tibaldi, Lorenzo, Joliot, Alain, Hensch, Takao Kurt, Prochiantz, Alain, Lee, Henry
Published 2021